Results 51 to 60 of about 78,616 (252)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Harnessing photoinduced electron transfer to optically determine protein sub-nanoscale atomic distances

Nature Communications, 2018
Current Förster resonance energy transfer (FRET)-based fluorescence spectroscopy methods are suffering from some limitations in the field of structural biology.
Antonios Pantazis, Karin Westerberg, Thorsten Althoff, Jeff Abramson, Riccardo Olcese   +4 more
doaj   +1 more source

A Review on the Application of Fluorescence Sensors Based on Fluorescence Resonance Energy Transfer Effect for Mycotoxins Detection [PDF]

Shipin Kexue
Mycotoxins are highly toxic and carcinogenic to humans and animals, and mycotoxin pollution in foods is difficult to prevent and control, which has sparked increasing concern. Therefore, it is necessary to detect mycotoxins in foods.
LU Meijun, WANG Tianlin, LI Tiange, QIAO Mingwu, MA Yan, HUANG Xianqing, FAN Jialin, SONG Lianjun
doaj   +1 more source

Irradiation‐Induced Spin Bath Evolution and as‐Grown Hydrogen Defects in CVD Diamond Revealed by NV‐Based DEER Spectroscopy

Advanced Functional Materials, EarlyView.
Here, we provide the reader with the current state of the art in the fabrication of high‐T2‐coherence diamond, optimized through the use of double electron–electron resonance (DEER) spectroscopy. We reveal the main as well as yet unidentified spin defects, the reduction of which is essential for reducing the spin bath and fabricating materials for ...
Olga Rubinas, Jeroen Prooth, Michael Petrov, Remy Vandebosch, Emilie Bourgeois, David Chvátil, Milos Nesladek   +6 more
wiley   +1 more source

Quantifying the inhibitory effect of Bcl‐xl on the action of Mff using live‐cell fluorescence imaging

FEBS Open Bio, 2019
Mitochondrial fission regulates mitochondrial function and morphology, and has been linked to apoptosis. The mitochondrial fission factor (Mff), a tail‐anchored membrane protein, induces excessive mitochondrial fission, contributing to mitochondrial ...
Yunyun Ma, Mengyan Du, Fangfang Yang, Zihao Mai, Chenshuang Zhang, Wenfeng Qu, Bin Wang, Xiaoping Wang, Tongsheng Chen   +8 more
doaj   +1 more source

Absence of clustering of phosphatidylinositol-(4,5)-bisphosphate in fluid phosphatidylcholine

Journal of Lipid Research, 2006
Phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P2] plays a key role in the modulation of actin polymerization and vesicle trafficking. These processes seem to depend on the enrichment of PI(4,5)P2 in plasma membrane domains. Here, we show that PI(4,5)P2
Faébio Fernandes, Luiés M.S. Loura, Alexander Fedorov, Manuel Prieto   +3 more
doaj   +1 more source

Ultra-Sensitive Hydrogen Peroxide Sensor Based on Peroxiredoxin and Fluorescence Resonance Energy Transfer

Applied Sciences, 2020
In this paper, a fluorescence resonance energy transfer (FRET)-based sensor for ultra-sensitive detection of H2O2 was developed by utilizing the unique enzymatic properties of peroxiredoxin (Prx) to H2O2. Cyan and yellow fluorescent protein (CFP and YFP)
Haijun Yu, Haoxiang Li, Yao Zhou, Shengmin Zhou, Ping Wang   +4 more
doaj   +1 more source

Water Adsorption‐Induced Color Sensor: Insight Into the Sensing Mechanism and Interfacial Engineering for Improved Responsiveness

Advanced Functional Materials, EarlyView.
We report a unique color‐sensing phenomenon of a TiO2/SbSI:Sb2S3 device utilizing X‐ray absorption. Based on the revealed penetration and adsorption of water onto TiO2, we successfully improved the color response speed and sensitivity by incorporating a hydrophilic polymer interlayer, thereby opening up opportunities for photodetection applications ...
Tai Kobayashi, Ryosuke Nishikubo, Yusuke Tomiyori, Fumitaka Ishiwari, Daisuke Asakura, Eiji Hosono, Miho Kitamura, Hisao Kiuchi, Yoshihisa Harada, Akinori Saeki   +9 more
wiley   +1 more source