Results 21 to 30 of about 182,643 (277)

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]

open access: yes, 2019
The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching   +17 more
core   +1 more source

Actin, α-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells [PDF]

open access: yes, 1975
During the spreading of a population of rat embryo cells, approximately 40% of the cells develop a strikingly regular network which precedes the formation of the straight actin filament bundles seen in the fully spread out cells.
Lazarides, Elias
core   +1 more source

Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization [PDF]

open access: yes, 2007
rom the identification of genes to the characterization of their functions and interactions. Developmental biologists have long used whole mount in situ hybridization (WISH) to determine gene expression patterns, as a vital tool for formulating and ...
Davis   +7 more
core   +1 more source

Development and optimization of a miniaturized western blot-based screening platform to identify regulators of post-translational modifications [PDF]

open access: yes, 2019
Post-translational modifications (PTMs) are fundamental traits of protein functionality and their study has been addressed using several approaches over the past years.
Gottifredi, Vanesa   +2 more
core   +1 more source

Single-cell western blotting. [PDF]

open access: yes, 2014
To measure cell-to-cell variation in protein-mediated functions, we developed an approach to conduct ∼10(3) concurrent single-cell western blots (scWesterns) in ∼4 h.
Herr, Amy E   +5 more
core   +2 more sources

Prevalence of Enteropathogens in Dogs Attending 3 Regional Dog Parks in Northern California. [PDF]

open access: yes, 2016
BackgroundThe prevalence and risk factors for infection with enteropathogens in dogs frequenting dog parks have been poorly documented, and infected dogs can pose a potential zoonotic risk for owners.Hypothesis/objectivesTo determine the prevalence and ...
Ahlmann, A   +6 more
core   +1 more source

A surgical model of short bowel syndrome induces a long-lasting increase in pancreatic beta-cell mass [PDF]

open access: yes, 2015
Several surgical techniques are used nowadays as a severe treatment for obesity and diabetes mellitus type 2. These techniques are aggressive due to drastic changes in the nutrient flow and non-reversible modifications on the digestive tube.
Aguilar Diosdado, Manuel   +6 more
core   +2 more sources

A High-Performance Fluorescence Immunoassay Based on the Relaxation of Quenching, Exemplified by Detection of Cardiac Troponin I

open access: yesSensors, 2016
The intramolecular fluorescence self-quenching phenomenon is a major drawback in developing high-performance fluorometric biosensors which use common fluorophores as signal generators.
Seung-Wan Kim   +4 more
doaj   +1 more source

Direct fluorescent antibody technique for differentiation between .ALPHA.- and .BETA.-hemolytic Streptococcus spp.

open access: yesFish Pathology, 1987
1. 直接蛍光抗体法(FAT)を応用して,各種病魚由来のαおよびβ型溶血性の Streptococcus spp.の識別ができるかどうかを検討した。2. その結果,ブリ由来のα 型溶血性株に対する標識抗体はα型菌株のみと,アユ由来のβ型菌株に対する標識抗体はアユ,ブリ,マイワシ由来のβ型溶血性株および S.iniae と特異的に反応した。3. したがって,両者はFATによっても識別できると考えられた。また, S.iniae はβ型溶血性菌株ときわめて類似の抗原構造を有することが示唆された。
Eijiro KAWAHARA, Riichi KUSUDA
openaire   +2 more sources

Diagnóstico microscópico de neumonía por Pneumocystis jirovecii en muestras de lavado broncoalveolar y lavado orofaríngeo de pacientes inmunocomprometidos con neumonía

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2011
Introducción. El diagnóstico de neumonía por Pneumocystis jirovecii se fundamenta en la visualización microscópica del hongo en secreciones respiratorias. Técnicas moleculares recientes también lo han detectado en muestras de orofaringe, pero su utilidad
Jenniffer Rodiño   +5 more
doaj   +1 more source

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