Results 211 to 220 of about 87,516 (306)

Protocol for in vitro immunofluorescence staining in a Transwell co-culture system. [PDF]

STAR Protoc
Ooi JYY, Tsang YS, McMahon LP, Wong L.
europepmc   +1 more source

Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis [PDF]

, 2019
Achilefu, Samuel, Guo, Junli, Libby, Peter, Liu, Cong-Lin, Liu, Jing, Liu, Tianxiao, Nahrendorf, Matthias, Shi, Guo-Ping, Sukhova, Galina K., Tang, Rui, Wang, Yunzhe, Wojtkiewicz, Gregory R., Zhang, Jin-Ying, Zhang, Xian   +13 more
core   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Brief guide to immunostaining. [PDF]

Mol Cells
Park G, Kim SS, Shim J, Lee SV.
europepmc   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

Advanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli, Andrea Pianetti, Elena Mancinelli, Anthea Villano, Matteo Vailati, Paola Lagonegro, Miryam Criado‐Gonzalez, Montserrat Climent, Hansel Comas‐Rojas, Leonardo Elia, Francesco Moccia, Gabriele Tullii, Maria Rosa Antognazza   +12 more
wiley   +1 more source

CRISPR-CISH: an in situ chromogenic DNA repeat detection system for research and life science education. [PDF]

Chromosome Res
Potlapalli BP, Dassau F, Fuchs J, Sushmoy DR, Houben A.   +4 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

High-Throughput Methods for Variant Functional Assessment in Cardiac Disease. [PDF]

Circ Genom Precis Med
Dolder RE, Friedman CE, Loiben AM, Yang KC, Glazer AM.   +4 more
europepmc   +1 more source

The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

Advanced Science, EarlyView.
BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang, Zijin Liu, Minshan Jin, Junting Liu, Shihao Wei, Dengmao Yang, Saiqi Yang, Yuan Guo, Mingxun Chen   +8 more
wiley   +1 more source

Progress of sex control techniques in mammals†. [PDF]

Biol Reprod
Chen H, Rushdi HE, Loor JJ, Teng Z, Liu S.   +4 more
europepmc   +1 more source