Results 31 to 40 of about 144,270 (311)

Etiological diagnosis reduces the use of antibiotics in infants with bronchiolitis

open access: yesClinics, 2012
OBJECTIVE: Acute bronchiolitis is a leading cause of infant hospitalization and is most commonly caused by respiratory syncytial virus. Etiological tests are not required for its diagnosis, but the influence of viral screening on the therapeutic approach
Ângela Esposito Ferronato   +4 more
doaj   +1 more source

Indirect Fluorescent Antibody Technique for Detection of RM Bacterium of Rainbow Trout (Salmo gairdneri)

open access: yes, 1974
An indirect fluorescent antibody technique was evaluated as a method for the rapid detection of RM bacterium of rainbow trout (Salmo gairdneri). Antibody produced by inoculating rabbits with washed RM bacterium antigen was combined with commercially ...
G. Wobeser, B. T. Rouse, G. R. Johnson
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Myxosoma cerebralis: Fluorescent Antibody Techniques for Antigen Recognition

open access: yes, 1978
Rabbits were immunized with antigens extracted from mature spores or prespore stages of Myxosoma cerebralis, and the resulting antisera and their globulins were used in direct and indirect fluorescent antibody techniques.
Ken Wolf, Maria E. Markiw
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Adult human case of toxocariasis with pulmonary migratory infiltrate and eosinophilia [PDF]

open access: yesVojnosanitetski Pregled, 2011
Introduction. Toxocariasis is a zoonosis which is in Serbia characterized with a very high infection rate of dogs and excessive contamination of the soil with the eggs of Toxocara canis, the agent of the disease.
Považan Đorđe   +6 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The anti-complement fluorescent antibody technique for the identification of mycobacteria

open access: yes, 1971
An anti-complement fluorescent antibody technique has been evaluated for the identification of mycobacteria. M. tuberculosis, M. avium, M. intracellulare, M. marinum, M. kansasii, M. scrofulaceum and M. fortuitum could readily be differentiated from each
Choi C.S., Francis J., Royal W.A.
core   +1 more source

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