Results 131 to 140 of about 210,311 (310)

STED imaging performance estimation by means of Fourier transform analysis [PDF]

open access: yes, 2017
Due to relatively high powers used in STED, biological samples may be affected by the illumination in the process of image acquisition. Similarly, the performance of the system may be limited by the sample itself.
Andilla, Jordi   +5 more
core   +4 more sources

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

open access: yesAdvanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav   +5 more
wiley   +1 more source

Comparison of Heparin Red, Azure A and Toluidine Blue assays for direct quantification of heparins in human plasma [PDF]

open access: yesarXiv, 2017
Heparins are are sulfated polysaccharides that have tremendous clinical importance as anticoagulant drugs. Monitoring of heparin blood levels can improve patient safety. In clinical practice, heparins are monitored indirectly by their inhibtory effect on coagulation proteases.
arxiv  

DESIGN AND DEVELOPMENT OF BODIPY-BASED FLUORESCENT PROBES FOR SENSING AND IMAGING OF CYANIDE, Zn (II) IONS, LYSOSOMAL pH AND CANCER CELLS [PDF]

open access: yes, 2015
BODIPY (4,4-Difluoro-3a,4a-diaza-s-indacene) dyes have gained lots of attention in application of fluorescence sensing and imaging in recent years because they possess many distinctive and desirable properties such as high extinction coefficient, narrow ...
Zhang, Jingtuo
core   +1 more source

The Cytoscan (TM) model E-II, a new reflectance microscope for intravital microscopy: Comparison with the standard fluorescence method [PDF]

open access: yes, 2000
The Cytoscan(TM) Model E-II (Cytometrics Inc., Philadelphia, Pa., USA) is a newly developed instrument which functions as an intravital microscope and is small and easily portable.
Harris, A. G.   +2 more
core   +1 more source

Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications

open access: yesAdvanced Biology, EarlyView.
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker   +7 more
wiley   +1 more source

Functionalizing Fluorophores for Protein Labeling [PDF]

open access: yes
Fluorescence is a valuable tool in the fields of chemistry and biology used to study reaction mechanisms and to visualize biologically relevant structures.
Gardiner, Meghan
core  

Quantum yield optimized fluorophores for site-specific labeling and super-resolution imaging

open access: yes, 2011
Single molecule applications, saturated pattern excitation microscopy, or stimulated emission depletion (STED) microscopy demand for bright and highly stable fluorescent dyes1,2.
Choquet, Daniel   +6 more
core   +3 more sources

Amplification‐Free, Sequencing‐Free, Detection of Viral RNAs with Variant Specification by Discrete Nanocounting

open access: yesAdvanced Functional Materials, EarlyView.
Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang   +9 more
wiley   +1 more source

A General Cyanine‐Based Platform for Designing Robust Dual‐Channel Near‐Infrared Fluorescent and Photoacoustic Probes

open access: yesAdvanced Functional Materials, EarlyView.
The study presents a general cyanine‐based platform CySN for designing robust dual‐channel near‐infrared fluorescent (NIRF) and photoacoustic (PA) probes with high ratiometric signals change. CySN enables the construction of highly sensitive and selective dual‐channel NIRF/PA probes for both small molecule and enzyme biomarkers (H2O2, esterase ...
Pingzhou Wu   +14 more
wiley   +1 more source

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