Results 61 to 70 of about 218,614 (297)

Ultrabright Fluorescent Silica Nanoparticles for Multiplexed Detection

open access: yesNanomaterials, 2020
Fluorescent tagging is a popular method in biomedical research. Using multiple taggants of different but resolvable fluorescent spectra simultaneously (multiplexing), it is possible to obtain more comprehensive and faster information about various ...
Saquib Ahmed M. A. Peerzade   +2 more
doaj   +1 more source

Quantum yield optimized fluorophores for site-specific labeling and super-resolution imaging

open access: yes, 2011
Single molecule applications, saturated pattern excitation microscopy, or stimulated emission depletion (STED) microscopy demand for bright and highly stable fluorescent dyes1,2.
Choquet, Daniel   +6 more
core   +3 more sources

Second harmonic generating (SHG) nanoprobes for in vivo imaging [PDF]

open access: yes, 2010
Fluorescence microscopy has profoundly changed cell and molecular biology studies by permitting tagged gene products to be followed as they function and interact.
Billinton   +26 more
core   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Taming fluorescent dyes with cucurbituril

open access: yesInternational Journal of Photoenergy, 2005
The potential of the supramolecular host molecule cucurbit[7]uril to serve as a stabilizing additive and enhancement agent was investigated for the following dyes in aqueous solution: rhodamine 6G, rhodamine 123, tetramethylrhodamine, cresyl violet ...
Werner M. Nau, Jyotirmayee Mohanty
doaj   +1 more source

Fluorogenic and Bioorthogonal Modification of RNA Using Photoclick Chemistry

open access: yesBiomolecules, 2020
A bromoaryltetrazole-modified uridine was synthesized as a new RNA building block for bioorthogonal, light-activated and postsynthetic modification with commercially available fluorescent dyes.
Katja Krell, Hans-Achim Wagenknecht
doaj   +1 more source

Fluorescent dyes specific for quadruplex DNA [PDF]

open access: yesNucleic Acids Research, 1998
Fluorescent dyes which are specific for duplex DNA have found a wide range of applications from staining gels to visualization of chromosomes. Porphyrin dyes have been found which are highly fluorescent in the presence of quadruplex but not duplex DNA. These dyes may offer a route to the specific detection of quadruplex DNA under biologically important
H, Arthanari   +3 more
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Fluorescence changes at flow cytometric analysis of samples from sentinel lymph nodes excised with indocyanine green and methylene blue guided mapping techniques

open access: yesFrontiers in Veterinary Science
IntroductionFlow cytometry (FC) has been used recently to assess percentages of infiltration by mast cells in sentinel lymph nodes (SLN) of dogs with mast cell tumors (MCT). SLN mapping often includes the use of different dyes such as methylene blue (MB)
Alessandra Ubiali   +4 more
doaj   +1 more source

Non-fused Phospholes as Fluorescent Probes for Imaging of Lipid Droplets in Living Cells

open access: yesFrontiers in Chemistry, 2017
Molecular tools for fluorescent imaging of specific compartments in cells are essential for understanding the function and activity of cells. Here, we report the synthesis of a series of pyridyl- and thienyl-substituted phospholes and the evaluation of ...
K. Peter R. Nilsson   +2 more
doaj   +1 more source

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