Charge-regulated hepatic γ-glutamyltranspeptidase fluorescent probe: <i>in vivo</i> staging of <i>Schistosoma</i> infection. [PDF]
Chem SciMa X +8 more
europepmc +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Turning on fluorescent probe for sensitive detection of streptomycin in pure, pharmaceutical formulations and human plasma. [PDF]
BMC ChemSamy B, Mabrouk MM, Hamid MAA, Ahmed HM.
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Dual-activated fluorescent probe for the study of the mechanism of SO<sub>2</sub> and NO in cisplatin resistance of nasopharyngeal carcinoma. [PDF]
RSC AdvWang X, Li X, Chen X, Wang D.
europepmc +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Preparation of carbon quantum dot fluorescent probe from Caesalpinia sappan L. for the detection of ciprofloxacin and antibacterial applications. [PDF]
Sci RepPei S +6 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Hyperspectral Fluorescence Imaging with a New Polarity-Ultrasensitive Fluorescent Probe. [PDF]
Adv Sci (Weinh)Zhou R +7 more
europepmc +1 more source