Results 251 to 260 of about 340,246 (317)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

A Benzimidazole-Based Fluorescent Probe for the Selective Recognition of Cobalt (II) Ions. [PDF]

Molecules
Zhu J, Wang HF, Zhang JX, Wang M, Zhuang YW, Suo ZG, He YW, Zhang YC, Wei M, Zhang HY.   +9 more
europepmc   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang, Shaoxin Tao, Qiujia Wang, Xiaoyu Xu, Hui Yao, Zheng Liu, Dawei Li, Zhandong Qiu, Jinming Han, Jiangwei Xia, Qi Wang, Jun Sun, Kai Shao, Jiao Li, Shishuang Ruan, Yi Zhong, Jun Guo, Shougang Guo, Yue Huang, Guoliang Chai, Tao Jin, Hongyu Zhou, Junwei Hao, Yinan Zhao   +23 more
wiley   +1 more source

A near-infrared fluorescent probe for dynamic HClO monitoring in epilepsy and high-throughput discovery of natural neuroprotectants. [PDF]

Redox Biol
Yin Q, Hou C, Zhang D, Li M, Zhang M, Ye T, Shi Y, Gai Z, Li B, Yan B.   +9 more
europepmc   +1 more source

Design of a NIR-I Viscosity-Sensitive Fluorescent Probe for Tracking Nuclear Physiological Changes During Different Cell Cycle Stages. [PDF]

Anal Chem
Yu J, Zhang H, Yuan S, Sun C, Zhang L, Luo C, Wang Q.   +6 more
europepmc   +1 more source

A highly specific fluorescent probe with facile pretreatment for rapid and accurate detection of sulfur dioxide residues in wolfberry (<i>Lycium barbarum L</i>.). [PDF]

Front Pharmacol
Ge Y, Chen W, Jiang L, Sun K, Liu G, Liu Y, Jin Y, Wang P, Zhang L, Zhang M, Ma L, Yu XA, Wang B.   +12 more
europepmc   +1 more source

Aloe vera derived carbon dots as multifunctional fluorescent probe for temperature, pH, and ferric ion sensing. [PDF]

Sci Rep
Rezk A, Elnimr MK, Atlam AS, Mosaad MM, Ghali M.   +4 more
europepmc   +1 more source

Developing a dichlorosalicylaldehyde-derived fluorescent probe for monitoring glutathione in a cellular pulmonary ventilation model. [PDF]

Front Chem
Zhou X, Zhang L, Lao Y, Zhou B, Zhu Z.
europepmc   +1 more source

HOCl and viscosity dual-responsive fluorescent probe for accurate discrimination between early hepatocellular carcinoma and acute liver injury. [PDF]

Mater Today Bio
Sun J, Cao L, Dong M, Liu Y, Wang Y, Zhan Y.   +5 more
europepmc   +1 more source

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Fluorescent lipoprotein probe

Analytical Biochemistry, 1982
Abstract The fluorescent cholesterol analog cholesta-5,7,9(11)triene-3-β-ol was used to label high-density and low-density lipoproteins in vivo (rabbit) and in vitro (human). Rabbit feeding experiments demonstrated that in vivo both the esterified and nonesterified forms of the fluorophore were incorporated by these particles.
R, Bergeron, J, Scott
openaire   +2 more sources