Results 51 to 60 of about 296,093 (307)
BioTechniques, 2015 Oligonucleotide microarrays allow the production of complex custom oligonucleotide libraries for nucleic acid detection–based applications such as fluorescence in situ hybridization (FISH). We have developed a PCR-free method to make single-stranded DNA (
Yusuf Murgha +6 more
doaj +1 more source
New Fluorescence Probes for Biomolecules [PDF]
Molecules, 2015 Steady state fluorescence measurements have been used for the investigation of interaction between the bovine serum albumin (BSA) and fluorescence probes: 3-hydroxy-2,4- bis[(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ6), 3-hydroxy- 2,4-bis[(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ7) and 3-hydroxy ...
Katarzyna Jurek +3 more
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescence and fluorescent life imaging probes for biomedical applications [PDF]
In my talk I will describe the development of a suite of fluorescent probes for the specific imaging of disease. This ranges from molecules that have been applied in vivo for the detection of cancer or fibrosis and bacterial lung infections, to probes ...
Bradley, M +1 more
core +2 more sources
Design strategies and progress on xanthene-based fluorescent probe for metal ions
Reviews in Analytical Chemistry, 2017 Metal ions play critical roles in numerous fundamental life processes. Hence, there is a great need to effectively monitor and image metal ions. Fluorescent probes are one of the most effective methods for measuring metal ions.
Ma Siyue +7 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Selenium:From fluorescent probes to biomedical application [PDF]
, 2023 Selenium (Se) is of fundamental importance to human health as an essential trace element, mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation in living systems and revealing cellular functions of SePs are of great ...
Ma, Li +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Technical Note on Quantum Dots for Multi-Color Fluorescence in situ Hybridization [PDF]
, 2009 Quantum dots (Qdots) are semiconductor nanocrystals, which are photo-stable, show bright fluorescence with narrow, symmetric emission spectra and are available in multiple resolvable colors.
Müller, Stefan +4 more
core +1 more source
Molecules, 2022 Carbon monoxide (CO) is a vital endogenous gaseous transmitter molecule involved in the regulation of various physiological and pathological processes in living biosystems.
Can Xie +5 more
doaj +1 more source