Results 61 to 70 of about 296,093 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Molecular fluorescent probes for monitoring pH changes in living cells [PDF]

, 2010
The availability of synthetic fluorescent probes and the development of powerful new approaches to microscopy have made fluorescence microscopy an essential tool for biomedical science and biology.
Yu, Fabiao, Yu, Chunwei, Chen, Lingxin, Wang, Rui   +3 more
core  

Simultaneous Real-Time Detection of Initiator- and Effector-Caspase Activation by Double Fluorescence Resonance Energy Transfer Analysis

Journal of Pharmacological Sciences, 2005
Fluorescence resonance energy transfer (FRET) with green fluorescent protein (GFP) variants has become widely used for biochemical research. In order to expand the choice of fluorescent range in FRET analysis, we designed various color versions of the ...
Hiroshi Kawai, Takuo Suzuki, Tetsu Kobayashi, Haruna Sakurai, Hisayuki Ohata, Kazuo Honda, Kazutaka Momose, Iyuki Namekata, Hikaru Tanaka, Koki Shigenobu, Ryu Nakamura, Takao Hayakawa, Toru Kawanishi   +12 more
doaj   +1 more source

Non-Cytotoxic Dibenzyl and Difluoroborate Curcuminoid Fluorophores Allow Visualization of Nucleus or Cytoplasm in Bioimaging

Molecules, 2020
Curcumin, the most important secondary metabolite isolated from Curcuma longa, is known for its numerous purported therapeutic properties and as a natural dye.
Marco A. Obregón-Mendoza, Imilla I. Arias-Olguín, M. Mirian Estévez-Carmona, William Meza-Morales, Yair Alvarez-Ricardo, Rubén A. Toscano, Francisco Arenas-Huertero, Julia Cassani, Raúl G. Enríquez   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Synthesis and properties of new fluorescent dyes and dye-labelled oligonucleotides [PDF]

, 2012
Fluorescence is widely used in DNA sequencing and genetic analysis. Novel fluorescence techniques for studying nucleic acids and other biologically important molecules are constantly being developed.
Gerowska, Marta
core  

Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB1R) [PDF]

The cannabinoid receptor type 1 (CB1R) is one of the central elements of the endocannabinoid system regulating a variety of signaling cascades. Extensive efforts on CB1R have validated its essential roles in physiology such as appetite regulation, pain ...
Marc, Nazare, Yelena , Mostinski, Calvin, Höffelmeyer, Tian , Hua, Jara , Bouma, Dmitry B. , Veprintsev, Axel, Hentsch, Thais , Gazzi, Laura H. , Heitman, Silke , Radetzki, Xiaoting , Li, Leonard , Mach, Malgorzata , Wasinska-Kalwa, Jens Peter , von Kries, Uwe, Grether, Anahid , Omran, Wolfgang , Guba, Marc , Vendrell, David A. , Sykes, Fabio , de Molnier, Cas , van der Horst   +20 more
core   +1 more source

Drug Derived Fluorescent Probes for the Specific Visualization of Cannabinoid Type 2 Receptor - A Toolbox Approach [PDF]

, 2019
Cannabinoid type 2 receptor (CB2R) is a fundamental part of the endocannabinoid signaling system (eCB system), and is known to play an important role in tissue injury, inflammation, cancer and pain.
Michael, Honer, Mario van der, Stelt, Jennifer, Beck, Eric, A. Kusznir, Sylwia, Huber, Kenneth, Atz, Matthias V., Westphal, Claudia, Korn, Svenja, Moes, Wolfgang, Guba, Daniela, Holzer, Marc, Nazare, Tom van der, Wel, Jürg, Gertsch, Klaus, Gawrisch, Yelena, Mostinski, Faye, Drawnel, Uwe, Grether, Patrick, Pfaff, Harpreet, Mandhair, Tamara, Miljuš, Irene, Benito-Cuesta, Catarina, Raposo, Christoph, Ullmer, Roman C., Sarott, Sergio, Oddi, Anto, Pavlovic, Julian, Romero, Bradley L., Hoare, Mauro, Maccarrone, Gabriella, Widmer, Erick M., Carreira, Zoltan V., Varga, Anja, Osterwald, Gazzi,, Thais, Dmitry B., Veprintsev, Cecilia J., Hillard, Marie, Weise, Teresa, Grande, Maira, Mexi, Natasha, Grimsey, Yurii, Saroz, Arne C., Rufer, André, Anker, Benjamin, Brennecke, David, Sykes, Elisabeth A., Zirwes, Pal, Pacher, Jürgen, Fingerle, Peter J., McCormick   +49 more
core   +1 more source

Recent Progress in Fluorescent Probes For Metal Ion Detection

Frontiers in Chemistry, 2022
All forms of life have absolute request for metal elements, because metal elements are instrumental in various fundamental processes. Fluorescent probes have been widely used due to their ease of operation, good selectivity, high spatial and temporal ...
Luanjing Li, Jiahe Wang, Shihan Xu, Chunxia Li, Biao Dong   +4 more
doaj   +1 more source

Fluorescent Probes of Biological Membranes [PDF]

Proceedings of the National Academy of Sciences, 1970
Fluorescent and phosphorescent probes that have readily interpretable emission properties can be specifically inserted into biological macromolecules to reveal facets of their structure and dynamics: (1) Proximity . Singlet-singlet and triplet-singlet energy transfer can serve as spectroscopic rulers in the 10-65 Å ...
A S, Waggoner, L, Stryer
openaire   +2 more sources