Results 61 to 70 of about 789,313 (250)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Recent Progress in Fluorescent Probes For Metal Ion Detection

Frontiers in Chemistry, 2022
All forms of life have absolute request for metal elements, because metal elements are instrumental in various fundamental processes. Fluorescent probes have been widely used due to their ease of operation, good selectivity, high spatial and temporal ...
Luanjing Li, Jiahe Wang, Shihan Xu, Chunxia Li, Biao Dong   +4 more
doaj   +1 more source

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

, 2017
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting the rapid growth of tumor cells and these two approaches are often ...
Yu, Fabiao, Lingxin Chen, Choo, Jaebum, Jaebum Choo, Yu, FB, Chen, Lingxin, Changjun Lv, Gao, Min, Lv, Changjun, Min Gao, Fabiao Yu   +10 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Sensing Performance and Efficiency of Two Energy Transfer-Based Two-Photon Fluorescent Probes for pH

Sensors, 2018
The design and synthesis of fluorescent probes for monitoring pH values inside living cells have attracted great attention, due to the important role pH plays in many biological processes. In this study, the optical properties of two different two-photon
Yujin Zhang, Wei Hu
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Synthesis and properties of new fluorescent dyes and dye-labelled oligonucleotides

, 2012
Fluorescence is widely used in DNA sequencing and genetic analysis. Novel fluorescence techniques for studying nucleic acids and other biologically important molecules are constantly being developed.
Gerowska, Marta
core   +1 more source

Boron nitride nanotubes as vehicles for intracellular delivery of fluorescent drugs and probes

, 2016
AIM: To evaluate the response of cells to boron nitride nanotubes (BNNTs) carrying fluorescent probes or drugs in their inner channel by assessment of the cellular localization of the fluorescent cargo, evaluation of the in vitro release and biological ...
Niskanen, J., Winnik, F. M., Maysinger, D., Xue, Y., Zhang, I., Golberg, D.   +5 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Drug Derived Fluorescent Probes for the Specific Visualization of Cannabinoid Type 2 Receptor - A Toolbox Approach [PDF]

, 2019
Cannabinoid type 2 receptor (CB2R) is a fundamental part of the endocannabinoid signaling system (eCB system), and is known to play an important role in tissue injury, inflammation, cancer and pain.
Michael, Honer, Mario van der, Stelt, Jennifer, Beck, Eric, A. Kusznir, Sylwia, Huber, Kenneth, Atz, Matthias V., Westphal, Claudia, Korn, Svenja, Moes, Wolfgang, Guba, Daniela, Holzer, Marc, Nazare, Tom van der, Wel, Jürg, Gertsch, Klaus, Gawrisch, Yelena, Mostinski, Faye, Drawnel, Uwe, Grether, Patrick, Pfaff, Harpreet, Mandhair, Tamara, Miljuš, Irene, Benito-Cuesta, Catarina, Raposo, Christoph, Ullmer, Roman C., Sarott, Sergio, Oddi, Anto, Pavlovic, Julian, Romero, Bradley L., Hoare, Mauro, Maccarrone, Gabriella, Widmer, Erick M., Carreira, Zoltan V., Varga, Anja, Osterwald, Gazzi,, Thais, Dmitry B., Veprintsev, Cecilia J., Hillard, Marie, Weise, Teresa, Grande, Maira, Mexi, Natasha, Grimsey, Yurii, Saroz, Arne C., Rufer, André, Anker, Benjamin, Brennecke, David, Sykes, Elisabeth A., Zirwes, Pal, Pacher, Jürgen, Fingerle, Peter J., McCormick   +49 more
core   +1 more source