Results 61 to 70 of about 473,147 (302)

A Review for In Vitro and In Vivo Detection and Imaging of Gaseous Signal Molecule Carbon Monoxide by Fluorescent Probes

Molecules, 2022
Carbon monoxide (CO) is a vital endogenous gaseous transmitter molecule involved in the regulation of various physiological and pathological processes in living biosystems.
Can Xie, Kun Luo, Libin Tan, Qiaomei Yang, Xiongjie Zhao, Liyi Zhou   +5 more
doaj   +1 more source

Multicolour interphase cytogenetics: 24 chromosome probes, 6 colours, 4 layers [PDF]

, 2011
From the late 1980s onwards, the use of DNA probes to visualise sequences on individual chromosomes (fluorescent in-situ hybridisation - FISH) revolutionised the study of cytogenetics.
A.R. Thornhill, Abruzzo, Arnold, Camps, Celeda, Cremer, D. Ioannou, D.K. Griffin, Dauwerse, DeSilva, E.J. Meershoek, Egozcue, Emmerich, Ersfeld, Fiegler, Finch, Finch, Foster, Gabriel, Griffin, Griffin, Griffin, Griffin, Griffin, Handyside, Harper, Harper, Harton, Jauch, Julien, Kallioniemi, Kearns, Kolluri, Langer, Lichter, M. Ellis, Mann, Matsuzaki, Muller, Munne, Munne, Munne, Munne, Nederlof, Nordgren, Olszewska, O’Keefe, Pinkel, Quilter, Rennstam, Roberts, Rodriguez, Rottger, Sbracia, Schardin, Schrock, Speicher, Syvanen, Tempest, Tsuchiya, Walling, Wienberg   +61 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Simultaneous Real-Time Detection of Initiator- and Effector-Caspase Activation by Double Fluorescence Resonance Energy Transfer Analysis

Journal of Pharmacological Sciences, 2005
Fluorescence resonance energy transfer (FRET) with green fluorescent protein (GFP) variants has become widely used for biochemical research. In order to expand the choice of fluorescent range in FRET analysis, we designed various color versions of the ...
Hiroshi Kawai, Takuo Suzuki, Tetsu Kobayashi, Haruna Sakurai, Hisayuki Ohata, Kazuo Honda, Kazutaka Momose, Iyuki Namekata, Hikaru Tanaka, Koki Shigenobu, Ryu Nakamura, Takao Hayakawa, Toru Kawanishi   +12 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Recent Progress in Fluorescent Probes For Metal Ion Detection

Frontiers in Chemistry, 2022
All forms of life have absolute request for metal elements, because metal elements are instrumental in various fundamental processes. Fluorescent probes have been widely used due to their ease of operation, good selectivity, high spatial and temporal ...
Luanjing Li, Jiahe Wang, Shihan Xu, Chunxia Li, Biao Dong   +4 more
doaj   +1 more source

Homologous cholinergic fluorescent probes. Synthesis and fluorescence properties [PDF]

FEBS Letters, 1978
The advantages of using specifically designed fluorescent molecules to probe ligand binding sites on proteins, have been recognised [1]. Cholinesterases [2-4], acetylcholine receptor rich fragments from Torpedo marmorata[5,6] and an acetylcholine binding lipoprotein [7] have been studied using fluorescent trialkylammonium ligands.
Narayanan, R, Balaram, P
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Recent Progress in the Rational Design of Biothiol-Responsive Fluorescent Probes

Molecules, 2023
Biothiols such as cysteine, homocysteine, and glutathione play significant roles in important biological activities, and their abnormal concentrations have been found to be closely associated with certain diseases, making their detection a critical task.
Wenzhi Xie, Jinyu Jiang, Dunji Shu, Yanjun Zhang, Sheng Yang, Kai Zhang   +5 more
doaj   +1 more source

Fluorescent Probes for Biological Imaging [PDF]

BioMed Research International, 2016
Owing to the high sensitivity, high resolution, and the wealth of contrast mechanisms, fluorescence imaging is the most versatile and widely used visualization modality to study the structure and function of biological systems and the molecular process in living organisms without perturbing them.
Xuanjun Zhang, Yupeng Tian, Jiangbo Yu, Zhen Yuan   +3 more
openaire   +2 more sources