Results 241 to 250 of about 1,322,177 (348)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

X-ray diffraction and time-resolved fluorescence analyses of Aequorea green fluorescent protein crystals.

, 1988
Mary A. Perozzo, Keith B. Ward, Richard B. Thompson, William W. Ward   +3 more
openalex   +1 more source

Development of a Turn-On Fluorescent Traceable Linker Employing <i>N</i>-Sulfanylethylcoumarinyl Amide for the Enrichment and Visualization of Target Proteins

, 2020
Takuya Morisaki, Akira Shigenaga, Akira Otaka   +2 more
openalex   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Tissue-Specific Fluorescent Protein Turnover in Free-Moving Flies. [PDF]

Insects
Bell KS, Ko S, Ali S, Bognar B, Khmelkov M, Rau N, Peng OK, Eyuboglu M, Paine J, Tong A, Saria A, Agrawal S, Davies KJA, Tower J.   +13 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Next-generation orange-to-far-red photoconvertible fluorescent protein for single-molecule microscopy and protein dynamic tracking. [PDF]

Sci Rep
Subach OM, Olumayowa F, Tang M, Qiao Y, Zhang Y, Vlaskina AV, Nikolaeva AY, Kononikhin AS, Agapova YK, Belousov A, Borshchevskiy V, Samygina VR, Perfilov MM, Mishin AS, Piatkevich KD, Subach FV.   +15 more
europepmc   +1 more source

Utilizing FLIM and fluorescent protein properties to reveal heterogeneity of densities and phases of bio-condensates [PDF]

Khalil Joron
openalex   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Chromophore charge-state switching through copper-dependent homodimerisation of an engineered green fluorescent protein. [PDF]

Chem Sci
Ahmed RD, Vitsupakorn D, Hartwell KD, Albalawi K, Rizkallah PJ, Watson PD, Jones DD.   +6 more
europepmc   +1 more source