Results 51 to 60 of about 586,937 (293)

Pure xenon hexafluoride prepared for thermal properties studies [PDF]

, 1967
Preparation of a xenon hexafluoride and sodium fluoride salt yields a sample of the highest possible purity for use in thermal measurements. The desired hexafluoride can easily be freed from the common contaminants, xenon tetra-fluoride, xenon difluoride,
Malm, J. G., Osborne, D. W., Schreiner, F.   +2 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Urinary fluoride output in children following the use of a dual-fluoride varnish formulation

Journal of Applied Oral Science, 2009
OBJECTIVE: This study evaluated the bioavailability of fluoride after topical application of a dual-fluoride varnish commercially available in Brazil, when compared to DuraphatTM. MATERIAL AND METHODS: The urinary fluoride output was evaluated in seven 5-
Kelly Polido Kaneshiro Olympio, Vanessa Eid da Silva Cardoso, Maria Fernanda Borro Bijella, Juliano Pelim Pessan, Alberto Carlos Botazzo Delbem, Marília Afonso Rabelo Buzalaf   +5 more
doaj   +1 more source

Caries-preventing effect of a hydroxyapatite-toothpaste in adults: a 18-month double-blinded randomized clinical trial

Frontiers in Public Health, 2023
BackgroundDental caries is a worldwide challenge for public health. The aim of this 18-month double-blinded, randomized, clinical trial was to compare the caries-preventing effect of a fluoride-free, hydroxyapatite toothpaste (test) and a toothpaste with
Elzbieta Paszynska, Malgorzata Pawinska, Joachim Enax, Frederic Meyer, Erik Schulze zur Wiesche, Theodor W. May, Bennett T. Amaechi, Hardy Limeback, Amadeusz Hernik, Justyna Otulakowska-Skrzynska, Anna Krahel, Inga Kaminska, Joanna Lapinska-Antonczuk, Ewa Stokowska, Maria Gawriolek   +14 more
doaj   +1 more source

Molecular Dynamics Simulation of Coherent Interfaces in Fluorite Heterostructures [PDF]

, 2014
The standard model of enhanced ionic conductivities in solid electrolyte heterostructures follows from a continuum mean-field description of defect distributions that makes no reference to crystalline structure.
Madden, Paul A., Morgan, Benjamin J.
core   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The color improvement of postdebonding white spot lesions after fluoride and casein phosphopeptide–amorphous calcium phosphate application

Journal of Advanced Pharmaceutical Technology & Research, 2021
White spots are common side effects of orthodontic treatment, and their presence after debonding appears unesthetic. This study aimed to quantify and compare the visual improvement in postdebonding white spot lesions following fluoride and casein ...
Haru Setyo Anggani, Putri Arifiani, Erwin Siregar   +2 more
doaj   +1 more source

Mechanism of C−F Reductive Elimination from Palladium(IV) Fluorides [PDF]

, 2010
The first systematic mechanism study of C−F reductive elimination from a transition metal complex is described. C−F bond formation from three different Pd(IV) fluoride complexes was mechanistically evaluated.
Benitez, Diego, Furuya, Takeru, Goddard, William A., III, Ritter, Tobias, Strom, Alexandra E., Tang, Pingping, Tkatchouk, Ekaterina   +6 more
core   +2 more sources

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source