Results 211 to 220 of about 51,702 (268)
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Metabolism of Fluorine 18 in Domestic Animals
American Journal of Physiology-Legacy Content, 1955Amounts of F/sup 18/ sufficient to permit studies up to 10 hours duration in domestic animals with non-toxic levels of total fluorine have become available from cyclotron production. The initial rate of disappearance of intravenously injected F/sup 18/ from the blood was found to be 41 and 32% of the dose/min.
J D, PERKINSON +4 more
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Preparation of carrier-free fluorine-18
The International Journal of Applied Radiation and Isotopes, 1977Abstract A method for the preparation of carrier-free fluorine-18 using a column of hydrous stannic oxide is described. The adsorption and desorption characteristics of the fluoride ion on the column has been investigated using F-18 as a tracer. The present study has confirmed that the fluoride ion is practically completely adsorbed on the column in ...
T H, Hsieh +3 more
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A cyclotron method for the production of fluorine-18
The International Journal of Applied Radiation and Isotopes, 1966Abstract Fluorine-18 is produced, with yields of up to 40 mc/hr, by the bombardment of water contained in a suitable target held in the external α-particle beam of a 30 MeV cyclotron: a method is described which is in routine use to produce samples for medical research purposes.
J C, Clark, D J, Silvester
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Journal of Inorganic and Nuclear Chemistry, 1964
Radiochemically pure 18F has been prepared by three different methods and its decay has been followed with β proportional counters and γ-ray counters in an effort to measure the half-life accurately. Analysis by a computer program that used the method of least squares gave a weighted mean half-life of 18F and a weighted standard deviation of the mean ...
J.D. Mahony, S.S. Markowitz
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Radiochemically pure 18F has been prepared by three different methods and its decay has been followed with β proportional counters and γ-ray counters in an effort to measure the half-life accurately. Analysis by a computer program that used the method of least squares gave a weighted mean half-life of 18F and a weighted standard deviation of the mean ...
J.D. Mahony, S.S. Markowitz
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Fluorine-18 Labeling of Peptides and Proteins
2006The pool of promising peptides worthy of investigation and evaluation for clinical use is continuously filled from different sources. Driven by the promising results obtained with peptides addressing somatostatin-2 receptor positive (sst2+) neuroendocrine tumours, other peptides targeting further receptor systems are being studied and evaluated ...
H J, Wester, M, Schottelius
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European Journal of Nuclear Medicine, 2000
Fluorine-18 labelled alpha-methyltyrosine (FMT) was developed for positron emission tomography (PET) imaging, and its potential for clinical application in patients with brain tumours has been demonstrated. This is the first trial to compare FMT with 18F-fluoro-2-deoxy-D-glucose (FDG) for the evaluation of musculoskeletal tumours. Seventy-five patients
H, Watanabe +10 more
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Fluorine-18 labelled alpha-methyltyrosine (FMT) was developed for positron emission tomography (PET) imaging, and its potential for clinical application in patients with brain tumours has been demonstrated. This is the first trial to compare FMT with 18F-fluoro-2-deoxy-D-glucose (FDG) for the evaluation of musculoskeletal tumours. Seventy-five patients
H, Watanabe +10 more
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Fluorine-18 Fluorodeoxyglucose Uptake in the Retractile Testis
Clinical Nuclear Medicine, 1999A 51-year-old man with a palpable mass in his right inguinal region had fluorine-18 fluorodeoxyglucose (F-18 FDG) whole-body positron emission tomography (PET) in our cancer screening program. FDG accumulated in the mass, suggesting a metabolically active lesion that was likely malignant.
H, Fujii +5 more
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[Fluorine-18 in radiopharmacy].
Annales pharmaceutiques francaises, 2008Positron emission tomography (PET) is a recent and expanding functional nuclear imaging technique. Its extensive development is related to the radiophysical properties fluorine 18 (18F) (weak energy of positron, sufficiently long physical half-life) and to the simple production and labeling procedures for 18F.
V, de Beco, D, Le Bars, J-M, Scherrmann
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Synthesis of fluorine-18 labeled 21-fluoroprogesterone
Steroids, 197721-Fluoroprogesterone has been synthesized by the nucleophilic displacement of the mesyl group of the 21-hydroxypregn-4-ene-3,20-dione 21-methanesulfonate by fluoride ion, as formed from the solvolysis of potassium fluoride in acetonitrile, using 18-Crown-6 as the catalyst.
L A, Spitznagle, C A, Marino
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Synthesis of the fluorine-18 labeled inhalation anesthetics
Applied Radiation and Isotopes, 1994Fourteen compounds (fluoroalkanes and fluoroethers), including the two most utilized inhalation anesthetics Isoflurane (CF3CHClOCF2H) and Halothane (CF3CHBrCl), have been labeled with fluorine-18 via a facile 18F-for-19F exchange reaction. The compounds include ten inhalation anesthetics which span a ten-fold range in potency and four structurally ...
M R, Satter +4 more
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