Results 21 to 30 of about 60,387 (338)
Background Thyroid cancer considered the 6th common cancer in female and represents approximately 1% of all cancers. Thyroid cancer is generally characterized by good prognosis, long term survival and low aggressiveness. Its prognosis is related to tumor
Amir Fathy Henfy Younis +2 more
doaj +1 more source
Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design. [PDF]
The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Wang Y, Lin Q, Shi H, Cheng D.
europepmc +2 more sources
Fluorine-18 Labelled Radioligands for PET Imaging of Cyclooxygenase-2. [PDF]
Molecular imaging probes enable the early and accurate detection of disease-specific biomarkers and facilitate personalized treatment of many chronic diseases, including cancer.
Kaur J, Bhardwaj A, Wuest F.
europepmc +2 more sources
Methods to Increase the Metabolic Stability of 18F-Radiotracers
The majority of pharmaceuticals and other organic compounds incorporating radiotracers that are considered foreign to the body undergo metabolic changes in vivo.
Manuela Kuchar, Constantin Mamat
doaj +1 more source
Erianin is an active constituent of Dendrobium candidum. In this work, 18F-fluoroethoxylerianin ([18F]FEE), a 18F-Labeled erianin analogue, was designed and synthesized to evaluate the properties of erianin and related analogues by in vivo PET imaging ...
Hui Nie +7 more
doaj +1 more source
Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [18F]fluorine via isotopic exchange or with radiometals (such as [68Ga]Gallium, [177Lu]Lutetium ...
Alexander Wurzer +8 more
doaj +1 more source
Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I
In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby +8 more
doaj +1 more source
Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase [PDF]
We thank EPSRC and the Scottish Imaging Network (SINAPSE) for grants. DO’H thanks the Royal Society for a Wolfson Research Merit Award and ST is grateful to the John and Kathleen Watson Scholarship for financial support.
Fleming, Ian N. +2 more
core +1 more source
Positron detection in silica monoliths for miniaturised quality control of PET radiotracers [PDF]
We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control.
Alexander, Richard +7 more
core +2 more sources
τBu₂SiF-Derivatized D₂-Receptor Ligands: The First SiFA-Containing Small Molecule Radiotracers for Target-Specific PET-Imaging [PDF]
The synthesis, radiolabeling and in vitro evaluation of new silicon-fluoride acceptor (SiFA) derivatized D-2-receptor ligands is reported. The SiFA-technology simplifies the introduction of fluorine-18 into target specific biomolecules for Positron ...
Bartenstein, Peter +10 more
core +2 more sources

