Results 21 to 30 of about 53,359 (237)

State of the art procedures towards reactive [18F]fluoride in PET tracer synthesis

EJNMMI Radiopharmacy and Chemistry, 2023
Background Positron emission tomography (PET) is a powerful, non-invasive preclinical and clinical nuclear imaging technique used in disease diagnosis and therapy assessment. Fluorine-18 is the predominant radionuclide used for PET tracer synthesis.
Lizeth Y. F. Haveman, Danielle J. Vugts, Albert D. Windhorst   +2 more
doaj   +1 more source

Prognostic value of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography imaging for predicting venous thromboembolism in children with lymphoma [PDF]

, 2023
Background: Positron emission tomography (PET)/computed tomography (CT) imaging can detect changes in arterial inflammation, but has not been used to evaluate chemotherapy-induced venous inflammation or assess risk for venous thromboembolism (VTE) in ...
Audino, Anthony N., Beall, Maren, Bobbey, Adam J., Chou, Ting-Heng, Deep, Kyra, Hardisky, Dariya, Janse, Sarah A., Kerlin, Bryce A., Nabavinia, Mahboubeh, Stacy, Mitchel R., Tram, Nguyen K.   +10 more
core   +1 more source

Fully Automated, High-Dose Radiosynthesis of [¹⁸F]PARPi

Pharmaceuticals, 2022
[18F]PARPi is currently undergoing clinical trials as a PET tracer for many applications. However, only manual radiosynthesis was reported; this has several drawbacks, including an increased risk of contamination from the operator, and the need to limit ...
Anna Pacelli, Fadi Zarrad, Corentin Warnier, Thibault Gendron, Muhammad Otabashi, Charles Vriamont, Alex Jackson, Wolfgang P. Fendler, Ken Herrmann, Michael Nader   +9 more
doaj   +1 more source

Isotopic Radiolabeling of the Antiretroviral Drug [¹⁸F]Dolutegravir for Pharmacokinetic PET Imaging

Pharmaceuticals, 2022
Deciphering the drug/virus/host interactions at infected cell reservoirs is a key leading to HIV-1 remission for which positron emission tomography (PET) imaging using radiolabeled antiretroviral (ARV) drugs is a powerful asset. Dolutegravir (DTG) is one
Marion Tisseraud, Sébastien Goutal, Thomas Bonasera, Maud Goislard, Delphine Desjardins, Roger Le Grand, Chris M. Parry, Nicolas Tournier, Bertrand Kuhnast, Fabien Caillé   +9 more
doaj   +1 more source

Advances in [¹⁸F]Trifluoromethylation Chemistry for PET Imaging

Molecules, 2021
Positron emission tomography (PET) is a preclinical and clinical imaging technique extensively used to study and visualize biological and physiological processes in vivo.
Felix Francis, Frank Wuest
doaj   +1 more source

Fluorine-18 Labeled Urea-Based Ligands Targeting Prostate-Specific Membrane Antigen (PSMA) with Increased Tumor and Decreased Renal Uptake

Pharmaceuticals, 2022
High expression of prostate-specific membrane antigen (PSMA) in prostate cancers prompted the development of the PSMA-targeted PET-imaging agent [18F]DCFPyL, which was recently approved by the FDA. Fluorine-18-labeled Lys–Urea–Glu-based oxime derivatives
Falguni Basuli, Tim E. Phelps, Xiang Zhang, Carolyn C. Woodroofe, Jyoti Roy, Peter L. Choyke, Rolf E. Swenson, Elaine M. Jagoda   +7 more
doaj   +1 more source

Importance of fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) in detection of post-thyroidectomy recurrence in differentiated thyroid cancer with negative radio-isotope iodine scan, yet, elevated serum thyroglobulin level

The Egyptian Journal of Radiology and Nuclear Medicine, 2022
Background Thyroid cancer considered the 6th common cancer in female and represents approximately 1% of all cancers. Thyroid cancer is generally characterized by good prognosis, long term survival and low aggressiveness. Its prognosis is related to tumor
Amir Fathy Henfy Younis, Ahmed Farid Yousif, Hamada Mohamed Khater   +2 more
doaj   +1 more source

PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[¹⁸F]fluoro-6-deoxy-D-fructose

Molecules, 2022
Fluorine-18 labeled 6-fluoro-6-deoxy-D-fructose (6-[18F]FDF) targets the fructose-preferred facilitative hexose transporter GLUT5, which is expressed predominantly in brain microglia and activated in response to inflammatory stimuli.
Amanda J. Boyle, Emily Murrell, Junchao Tong, Christin Schifani, Andrea Narvaez, Melinda Wuest, Frederick West, Frank Wuest, Neil Vasdev   +8 more
doaj   +1 more source

[18F]Tosyl fluoride as a versatile [18F]fluoride source for the preparation of 18F-labeled radiopharmaceuticals [PDF]

, 2023
Positron emission tomography (PET) is an in vivo imaging technology that utilizes positron-emitting radioisotope-labeled compounds as PET radiotracers that are commonly used in clinic and in various research areas, including oncology, cardiology, and ...
Chu, Wenhua, Katzenellenbogen, John A, Schwarz, Sally, Xu, Jinbin, Zhou, Dong   +4 more
core   +2 more sources

Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents [PDF]

, 2008
Nanoparticles containing fluorine-18 were prepared from block copolymers made by ring opening metathesis polymerization (ROMP). Using the fast initiating ruthenium metathesis catalyst (H_2IMes)(pyr)_2(Cl)_2Ru=CHPh, low polydispersity amphiphilic block ...
, X. K., A. Guo, A. M. Morawski, A. M. Smith, C. C. Lee, C. Slugovc, C. W. Bielawski, C. W. Bielawski, D. F. Baban, D. W. Bartlett, E. D. Pressly, E. M. Jagoda, E. M. Rohren, F. Henselwood, F. M. Menger, G. J. Liu, H. A. Nabi, H. D. Maynard, H. Kobayashi, H. Maeda, H. Maeda, H. R. Ihre, I. Brigger, J. A. Love, J. B. Matson, J. Heidel, J. R. Heath, K. D. Camm, K. Fukukawa, L. Cai, L. H. Reddy, M. F. Ilker, M. Ferrari, M. L. Adams, M. L. Schipper, M. Licciardi, M. Rawat, N. K. Jain, N. Malik, R. Gref, R. Sinha, S. K. Hobbs, S. M. Lee, S. M. Moghimi, T. L. Choi, V. Bagalkot, V. P. Tochilin, V. P. Torchilin, V. P. Torchilin, V. P. Torchilin, W. J. M. Mulder, W. S. Seo, X. Michalet, Y. Matsumura, Z. Yang   +54 more
core   +3 more sources