Results 21 to 30 of about 3,321,367 (333)
Methods to Increase the Metabolic Stability of 18F-Radiotracers
Molecules, 2015 The majority of pharmaceuticals and other organic compounds incorporating radiotracers that are considered foreign to the body undergo metabolic changes in vivo.
Manuela Kuchar, Constantin Mamat
doaj +1 more source
SynOpen, 2022 Erianin is an active constituent of Dendrobium candidum. In this work, 18F-fluoroethoxylerianin ([18F]FEE), a 18F-Labeled erianin analogue, was designed and synthesized to evaluate the properties of erianin and related analogues by in vivo PET imaging ...
Hui Nie +7 more
doaj +1 more source
EJNMMI Research, 2020 Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [18F]fluorine via isotopic exchange or with radiometals (such as [68Ga]Gallium, [177Lu]Lutetium ...
Alexander Wurzer +8 more
doaj +1 more source
Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I
Pharmaceuticals, 2021 In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby +8 more
doaj +1 more source
Fluorine-18 labelled building blocks for PET tracer synthesis.
Chemical Society Reviews, 2017 Positron emission tomography (PET) is an important driver for present day healthcare. Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview of the available radiochemistry methodology is a prerequisite for selection of ...
Dion van der Born +5 more
semanticscholar +1 more source
Frontiers in Chemistry, 2018 Tumor cells have an increased nutritional demand for amino acids (AAs) to satisfy their rapid proliferation. Positron-emitting nuclide labeled AAs are interesting probes and are of great importance for imaging tumors using positron emission tomography ...
Aixia Sun, Xiang Liu, Ganghua Tang
semanticscholar +1 more source
Radiosynthesis of [18F]-Labelled Pro-Nucleotides (ProTides)
Molecules, 2020 Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success.
Alessandra Cavaliere +7 more
doaj +1 more source
A New Method for 18FDG generating using Geant4/ Gate7
Basic & Clinical Cancer Research, 2023 Fluorine 18-deoxyglucose is often used in Positron Emission Tomography devices. Positron Emission Tomography imaging is one of the useful tools which is used for cancer detection and its management.
Abuzar Shakeri +3 more
doaj
EJNMMI Radiopharmacy and Chemistry, 2022 Background Positron emission tomography (PET) is a powerful tool in medical imaging, especially in combination with the PET radionuclide fluorine-18 that possesses optimal characteristics.
Carsten Sven Kramer +3 more
doaj +1 more source