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The Egyptian Journal of Radiology and Nuclear Medicine, 2022 Background Thyroid cancer considered the 6th common cancer in female and represents approximately 1% of all cancers. Thyroid cancer is generally characterized by good prognosis, long term survival and low aggressiveness. Its prognosis is related to tumor
Amir Fathy Henfy Younis +2 more
doaj +1 more source
SynOpen, 2022 Erianin is an active constituent of Dendrobium candidum. In this work, 18F-fluoroethoxylerianin ([18F]FEE), a 18F-Labeled erianin analogue, was designed and synthesized to evaluate the properties of erianin and related analogues by in vivo PET imaging ...
Hui Nie +7 more
doaj +1 more source
Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents [PDF]
, 2008 Nanoparticles containing fluorine-18 were prepared from block copolymers made by ring opening metathesis polymerization (ROMP). Using the fast initiating ruthenium metathesis catalyst (H_2IMes)(pyr)_2(Cl)_2Ru=CHPh, low polydispersity amphiphilic block ...
, X. K. +54 more
core +3 more sources
Development of PDT/PET theranostics: synthesis and biological evaluation of an ¹⁸F-radiolabeled water soluble porphyrin [PDF]
, 2015 Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission ...
Allott, Louis +7 more
core +1 more source
EJNMMI Research, 2020 Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [18F]fluorine via isotopic exchange or with radiometals (such as [68Ga]Gallium, [177Lu]Lutetium ...
Alexander Wurzer +8 more
doaj +1 more source
Synthesis, in vitro evaluation, and radiolabeling of fluorinated puromycin analogues: potential candidates for PET imaging of protein synthesis [PDF]
, 2016 There is currently no ideal radiotracer for imaging protein synthesis rate (PSR) by positron emission tomography (PET). Existing fluorine-18 labelled amino acid-based radiotracers predominantly visualize amino acid transporter processes, and in many ...
Alan C. Perkins +8 more
core +3 more sources
Methods to Increase the Metabolic Stability of 18F-Radiotracers
Molecules, 2015 The majority of pharmaceuticals and other organic compounds incorporating radiotracers that are considered foreign to the body undergo metabolic changes in vivo.
Manuela Kuchar, Constantin Mamat
doaj +1 more source
Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I
Pharmaceuticals, 2021 In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby +8 more
doaj +1 more source
In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography [PDF]
, 2008 The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor ...
Bergstr m +26 more
core +3 more sources
Fluorine-18 labelled building blocks for PET tracer synthesis.
Chemical Society Reviews, 2017 Positron emission tomography (PET) is an important driver for present day healthcare. Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview of the available radiochemistry methodology is a prerequisite for selection of ...
Dion van der Born +5 more
semanticscholar +1 more source