Results 21 to 30 of about 60,387 (338)

Importance of fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) in detection of post-thyroidectomy recurrence in differentiated thyroid cancer with negative radio-isotope iodine scan, yet, elevated serum thyroglobulin level

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2022
Background Thyroid cancer considered the 6th common cancer in female and represents approximately 1% of all cancers. Thyroid cancer is generally characterized by good prognosis, long term survival and low aggressiveness. Its prognosis is related to tumor
Amir Fathy Henfy Younis   +2 more
doaj   +1 more source

Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design. [PDF]

open access: yesFront Chem, 2022
The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Wang Y, Lin Q, Shi H, Cheng D.
europepmc   +2 more sources

Fluorine-18 Labelled Radioligands for PET Imaging of Cyclooxygenase-2. [PDF]

open access: yesMolecules, 2022
Molecular imaging probes enable the early and accurate detection of disease-specific biomarkers and facilitate personalized treatment of many chronic diseases, including cancer.
Kaur J, Bhardwaj A, Wuest F.
europepmc   +2 more sources

Methods to Increase the Metabolic Stability of 18F-Radiotracers

open access: yesMolecules, 2015
The majority of pharmaceuticals and other organic compounds incorporating radiotracers that are considered foreign to the body undergo metabolic changes in vivo.
Manuela Kuchar, Constantin Mamat
doaj   +1 more source

Radiosynthesis and Tumor MicroPET/CT Imaging of 18F-Fluoro­ethoxylerianin, an 18F-Labeled Erianin Analogue

open access: yesSynOpen, 2022
Erianin is an active constituent of Dendrobium candidum. In this work, 18F-fluoroethoxylerianin ([18F]FEE), a 18F-Labeled erianin analogue, was designed and synthesized to evaluate the properties of erianin and related analogues by in vivo PET imaging ...
Hui Nie   +7 more
doaj   +1 more source

Preclinical comparison of four [18F, natGa]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics

open access: yesEJNMMI Research, 2020
Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [18F]fluorine via isotopic exchange or with radiometals (such as [68Ga]Gallium, [177Lu]Lutetium ...
Alexander Wurzer   +8 more
doaj   +1 more source

Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I

open access: yesPharmaceuticals, 2021
In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby   +8 more
doaj   +1 more source

Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase [PDF]

open access: yes, 2016
We thank EPSRC and the Scottish Imaging Network (SINAPSE) for grants. DO’H thanks the Royal Society for a Wolfson Research Merit Award and ST is grateful to the John and Kathleen Watson Scholarship for financial support.
Fleming, Ian N.   +2 more
core   +1 more source

Positron detection in silica monoliths for miniaturised quality control of PET radiotracers [PDF]

open access: yes, 2016
We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [⁶⁸Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control.
Alexander, Richard   +7 more
core   +2 more sources

τBu₂SiF-Derivatized D₂-Receptor Ligands: The First SiFA-Containing Small Molecule Radiotracers for Target-Specific PET-Imaging [PDF]

open access: yes, 2011
The synthesis, radiolabeling and in vitro evaluation of new silicon-fluoride acceptor (SiFA) derivatized D-2-receptor ligands is reported. The SiFA-technology simplifies the introduction of fluorine-18 into target specific biomolecules for Positron ...
Bartenstein, Peter   +10 more
core   +2 more sources

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