Results 11 to 20 of about 51,702 (268)

Importance of fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) in detection of post-thyroidectomy recurrence in differentiated thyroid cancer with negative radio-isotope iodine scan, yet, elevated serum thyroglobulin level

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2022
Background Thyroid cancer considered the 6th common cancer in female and represents approximately 1% of all cancers. Thyroid cancer is generally characterized by good prognosis, long term survival and low aggressiveness. Its prognosis is related to tumor
Amir Fathy Henfy Younis   +2 more
doaj   +1 more source

Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives

open access: yesMolecules, 2023
The use of radiolabeled glucose for PET imaging resulted in the most commonly used tracer in the clinic, 2-deoxy-2-[18F]fluoroglucose (FDG). More recently, other radiolabeled sugars have been reported for various applications, including imaging tumors ...
Xiang Zhang   +9 more
doaj   +1 more source

Methods to Increase the Metabolic Stability of 18F-Radiotracers

open access: yesMolecules, 2015
The majority of pharmaceuticals and other organic compounds incorporating radiotracers that are considered foreign to the body undergo metabolic changes in vivo.
Manuela Kuchar, Constantin Mamat
doaj   +1 more source

Radiosynthesis and Tumor MicroPET/CT Imaging of 18F-Fluoro­ethoxylerianin, an 18F-Labeled Erianin Analogue

open access: yesSynOpen, 2022
Erianin is an active constituent of Dendrobium candidum. In this work, 18F-fluoroethoxylerianin ([18F]FEE), a 18F-Labeled erianin analogue, was designed and synthesized to evaluate the properties of erianin and related analogues by in vivo PET imaging ...
Hui Nie   +7 more
doaj   +1 more source

Preclinical comparison of four [18F, natGa]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics

open access: yesEJNMMI Research, 2020
Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [18F]fluorine via isotopic exchange or with radiometals (such as [68Ga]Gallium, [177Lu]Lutetium ...
Alexander Wurzer   +8 more
doaj   +1 more source

Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I

open access: yesPharmaceuticals, 2021
In the struggle to understand and accurately diagnose Parkinson′s disease, radiopharmaceuticals and medical imaging techniques have played a major role. By being able to image and quantify the dopamine transporter density, noninvasive diagnostic imaging ...
Klas Bratteby   +8 more
doaj   +1 more source

Radiosynthesis of [18F]-Labelled Pro-Nucleotides (ProTides)

open access: yesMolecules, 2020
Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success.
Alessandra Cavaliere   +7 more
doaj   +1 more source

Preparation of Fluorine-18

open access: yesJournal of Nuclear Science and Technology, 1964
Fluorine-18 was prepared by neutron irradiation of lithium carbonate in the reactor JRR-1. Five grams of lithium carbonate was irradiated for 2hr with a thermal neutron flux of 6×1011 n/cm2/sec.
openaire   +2 more sources

Fluorine-18: an untapped resource in inorganic chemistry [PDF]

open access: yesChemical Communications, 2018
Advances in the field of fluorine chemistry have been applied extensively to the syntheses of 18 F-labelled organic compounds and radiopharmaceuticals.
Cassis Varlow   +4 more
openaire   +2 more sources

Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design

open access: yesFrontiers in Chemistry, 2022
The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Yunze Wang   +11 more
doaj   +1 more source

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