Results 1 to 10 of about 307,140 (314)

Feasibility of imaging synaptic density in the human spinal cord using [11C]UCB-J PET

EJNMMI Physics, 2022
Purpose Neuronal damage and synapse loss in the spinal cord (SC) have been implicated in spinal cord injury (SCI) and neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS).
Samantha Rossano, Takuya Toyonaga, Jason Bini, Nabeel Nabulsi, Jim Ropchan, Zhengxin Cai, Yiyun Huang, Richard E. Carson   +7 more
doaj   +1 more source

Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation

EJNMMI Research, 2022
Highlights In a focal rat DTH-EAE model of neuroinflammation, dimethyl fumarate decreases the uptake of TSPO PET tracer [18F]GE-180 in the short term. Long-term [18F]GE-180 follow-up did not indicate a treatment effect.
S. K. Vainio, A. M. Dickens, M. Matilainen, F. R. López-Picón, R. Aarnio, O. Eskola, O. Solin, D. C. Anthony, J. O. Rinne, L. Airas, M. Haaparanta-Solin   +10 more
doaj   +1 more source

ImmunoPET Directed to the Brain: A New Tool for Preclinical and Clinical Neuroscience

Biomolecules, 2023
Immuno-positron emission tomography (immunoPET) is a non-invasive in vivo imaging method based on tracking and quantifying radiolabeled monoclonal antibodies (mAbs) and other related molecules, such as antibody fragments, nanobodies, or affibodies ...
Ángel García de Lucas, Urpo Lamminmäki, Francisco R. López-Picón   +2 more
doaj   +1 more source

Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand 11C-UCB-J

EJNMMI Research, 2020
The ability to quantify synaptic density in vivo in human adults and adolescents is of vital importance to understanding neuropsychiatric disorders.
Jason Bini, Daniel Holden, Kathryn Fontaine, Tim Mulnix, Yihuan Lu, David Matuskey, Jim Ropchan, Nabeel Nabulsi, Yiyun Huang, Richard E. Carson   +9 more
doaj   +1 more source

Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation (4Is)-related cardiovascular diseases: a joint collaboration of the EACVI and the EANM [PDF]

, 2022
With this document, we provide a standard for PET/(diagnostic) CT imaging procedures in cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with dysfunctional innervation (4Is).
Christoph Rischpler, Paola A. Erba, Panagiotis Georgoulias, Hein J. Verberne, Mark Lubberink, Marc R. Dweck, Fabien Hyafil, Oliver Gaemperli, 4Is Cardiovascular Imaging: a joint initiative of the European Association of Cardiovascular Imaging (EACVI) and the European Association of Nuclear Medicine (EANM), Jan Bucerius, Alessia Gimelli, Riemer H. J. A. Slart, Gilbert Habib, Tanja Kero, Antti Saraste, Andor W. J. M. Glaudemans, Olivier Gheysens   +16 more
core   +1 more source

18F-PSMA-1007 PET/CT Performance on Risk Stratification Discrimination and Distant Metastases Prediction in Newly Diagnosed Prostate Cancer

Frontiers in Oncology, 2021
ObjectiveTo evaluate the prediction performance of 18F-PSMA-1007 PET/CT and clinicopathologic characteristics on prostate cancer (PCa) risk stratification and distant metastatic prediction.Materials and MethodsA retrospective analysis was performed on ...
Zhuonan Wang, Anqi Zheng, Yunxuan Li, Weixuan Dong, Xiang Liu, Wang Yuan, Fan Gao, Xiaoyi Duan   +7 more
doaj   +1 more source

Adaptive noise depression for functional brain network estimation

Frontiers in Psychiatry, 2023
Autism spectrum disorder (ASD) is one common psychiatric illness that manifests in neurological and developmental disorders, which can last throughout a person's life and cause challenges in social interaction, communication, and behavior.
Di Ma, Di Ma, Liling Peng, Xin Gao
doaj   +1 more source

The value of 18F-PSMA-1007 PET/CT in identifying non-metastatic high-risk prostate cancer

EJNMMI Research, 2020
Background Clinical management decisions on prostate cancer (PCa) are often based on a determination of risk. 68Ga-prostate-specific membrane antigen (PSMA)-11-positron emission tomography (PET)/computer tomography (CT) is an attractive modality to ...
Jun-jie Hong, Bo-le Liu, Zhi-qiang Wang, Kun Tang, Xiao-wei Ji, Wei-wei Yin, Jie Lin, Xiang-wu Zheng   +7 more
doaj   +1 more source

[18F]Fluoride uptake in various bone types and soft tissues in rat

EJNMMI Research, 2023
Background In the development of new 18F-labelled tracers, it is important to assess the amount of released [18F]fluoride taken up in the bones of experimental animals because all 18F-labelled PET-tracers are prone, to lesser or higher degree, to undergo
Nina Savisto, Tove J. Grönroos, Vesa Oikonen, Johan Rajander, Eliisa Löyttyniemi, Jörgen Bergman, Sarita Forsback, Olof Solin, Merja Haaparanta-Solin   +8 more
doaj   +1 more source

Going beyond the borders : field-of-view extension in MR/PET hybrid imaging [PDF]

, 2012
The recent combination of Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) is of emerging interest in clinical routine. On the one hand, MRI is a widely-used diagnostic tool in medical practice.
Blumhagen, Jan Ole
core   +1 more source