Results 41 to 50 of about 307,140 (314)

Cessation of anti-VLA-4 therapy in a focal rat model of multiple sclerosis causes an increase in neuroinflammation

EJNMMI Research, 2019
Background Positron emission tomography (PET) can be used for in vivo evaluation of the pathology associated with multiple sclerosis. We investigated the use of longitudinal PET imaging and the 18-kDa translocator protein (TSPO) binding radioligand [18F ...
S. K. Vainio, A. M. Dickens, J. Tuisku, O. Eskola, O. Solin, E. Löyttyniemi, D. C. Anthony, J. O. Rinne, L. Airas, M. Haaparanta-Solin   +9 more
doaj   +1 more source

Data-driven analysis of kappa opioid receptor binding in major depressive disorder measured by positron emission tomography

Translational Psychiatry, 2021
Preclinical studies have implicated kappa opioid receptors (KORs) in stress responses and depression-related behaviors, but evidence from human studies is limited.
Kelly Smart, Ashley Yttredahl, Maria A. Oquendo, J. John Mann, Ansel T. Hillmer, Richard E. Carson, Jeffrey M. Miller   +6 more
doaj   +1 more source

Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA

EJNMMI Research
Background P2X7 receptor has emerged as a potentially superior PET imaging marker to TSPO, the gold standard for imaging glial reactivity. [11C]SMW139 is the most recently developed radiotracer to image P2X7 receptor.
Obada M. Alzghool, Richard Aarnio, Jatta S. Helin, Saara Wahlroos, Thomas Keller, Markus Matilainen, Junel Solis, Jonathan J. Danon, Michael Kassiou, Anniina Snellman, Olof Solin, Juha O. Rinne, Merja Haaparanta-Solin   +12 more
doaj   +1 more source

Stability evaluation of [18F]FDG: literature study, stability studies from two different PET centres and future recommendations

EJNMMI Radiopharmacy and Chemistry, 2022
Background The need for a stability evaluation of [18F]FDG is evident. The main purpose of this study was to make recommendations for determining the shelf life based on the available stability literature and our own two-centre stability studies. Results
Jes G. Holler, Børge Renmælmo, Richard Fjellaksel   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Isolated single lobe hyperplasia of the thyroid gland, presenting as anterior mediastinal mass, detected on positron emission tomography-computed tomography scan

World Journal of Nuclear Medicine, 2020
We report a case who presented with facial swelling and breathlessness. Recent chest X-ray was suggestive of soft-tissue in the mediastinum. In view of the suspicion of mass being neoplastic, the patient was referred for positron emission tomography ...
Nitin Gupta, Dharmender Malik, Ritu Verma, Sunila Jain   +3 more
doaj   +1 more source

Evaluation of three methods for delineation and attenuation estimation of the sinus region in MR-based attenuation correction for brain PET-MR imaging [PDF]

, 2022
Background Attenuation correction is crucial in quantitative positron emission tomography-magnetic resonance (PET-MRI) imaging. We evaluated three methods to improve the segmentation and modelling of the attenuation coefficients in the nasal sinus region.
Lindén Jani, Teräs Mika, Teuho Jarmo, Klén Riku   +3 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

The reconfiguration pattern of individual brain metabolic connectome for Parkinson's disease identification

MedComm, 2023
18F‐Fluorodeoxyglucose positron emission tomography (18F‐FDG PET) is widely employed to reveal metabolic abnormalities linked to Parkinson's disease (PD) at a systemic level.
Weikai Li, Yongxiang Tang, Liling Peng, Zhengxia Wang, Shuo Hu, Xin Gao   +5 more
doaj   +1 more source

Models for the PET quantitative imaging of the adenosine receptor radioligand [11C] SCH442416 in humans [PDF]

, 2010
Positron Emission Tomography is an important imaging technique, that enables regional function to be assayed in a fully quantitative and noninvasive manner. It is based on the use of radioactive tracers: [11C]SCH442416, which is the compound of interest
Boscolo Galazzo, Ilaria
core