Results 21 to 30 of about 3,257,292 (311)

Radiosynthesis of [¹⁸F]-Labelled Pro-Nucleotides (ProTides)

Molecules, 2020
Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success.
Alessandra Cavaliere, Katrin C. Probst, Stephen J. Paisey, Christopher Marshall, Abdul K. H. Dheere, Franklin Aigbirhio, Christopher McGuigan, Andrew D. Westwell   +7 more
doaj   +1 more source

Fluorine-18: an untapped resource in inorganic chemistry [PDF]

Chemical Communications, 2018
Advances in the field of fluorine chemistry have been applied extensively to the syntheses of 18F-labelled organic compounds and radiopharmaceuticals.
Cassis Varlow, Daniel Szames, Kenneth Dahl, Vadim Bernard-Gauthier, Neil Vasdev   +4 more
openaire   +2 more sources

Fluorine in silicate glasses: A multinuclear nuclear magnetic resonance study [PDF]

, 1992
Anhydrous nepheline, jadeite, and albite glasses doped with F as well as hydrous F-containing haplogranitic glasses were investigated using 19F combined rotation and multiple-pulse spectroscopy; 19F → 29Si cross-polarization/magic angle spinning (MAS ...
Merwin, Lawrence, Sebald, Angelika, Dingwell, Donald B., Schaller, Thorsten, Knöller, W., Keppler, Hans   +5 more
core   +1 more source

Fluorine-18 and Radiometal Labeling of Biomolecules via Disulfide Rebridging

, 2023
Biomolecules labeled with positron-emitting radionuclides like fluorine-18 or radiometals like copper-64 and zirconium-89 are increasingly employed in nuclear medicine for diagnosis purposes.
Soizic Martin Aubert, Steven Dubois (2718487), Caroline Denis, Charles Truillet, Charles Truillet (1355238), Mylène Richard, Hervé Nozach (3116982), Steven Dubois, Bertrand Kuhnast, Mylène Richard (13293104), Soizic Martin Aubert (17287539), Caroline Denis (16125047), Hervé Nozach, Bertrand Kuhnast (1523902)   +13 more
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Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design

Frontiers in Chemistry, 2022
The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Yunze Wang, Yunze Wang, Yunze Wang, Qingyu Lin, Qingyu Lin, Qingyu Lin, Hongcheng Shi, Hongcheng Shi, Hongcheng Shi, Dengfeng Cheng, Dengfeng Cheng, Dengfeng Cheng   +11 more
doaj   +1 more source

Organometallic fluorine-18 bonds in 18F-radiochemistry [PDF]

, 2021
Fluorine-18 is by far the most widely exploited radionuclide in PET (positron emission tomography) radiochemistry. The physical half-life of fluorine-18 allows for chemical manipulation within a restricted timeframe, and cyclotron-produced fluoride ion
전중현
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Preparation of Fluorine-18

Journal of Nuclear Science and Technology, 1964
Fluorine-18 was prepared by neutron irradiation of lithium carbonate in the reactor JRR-1. Five grams of lithium carbonate was irradiated for 2hr with a thermal neutron flux of 6×1011 n/cm2/sec. An alumina column was used to separate 18F from the irradiated material.
openaire   +2 more sources

Fluorination of silyl prosthetic groups by fluorine mediated silyl ether linker cleavage: a concept study with conditions applicable in radiofluorination

EJNMMI Radiopharmacy and Chemistry, 2022
Background Positron emission tomography (PET) is a powerful tool in medical imaging, especially in combination with the PET radionuclide fluorine-18 that possesses optimal characteristics.
Carsten Sven Kramer, Luca Greiner, Klaus Kopka, Martin Schäfer   +3 more
doaj   +1 more source

Strategies for radiolabelling antibody, antibody fragments and affibodies with fluorine-18 as tracers for positron emission tomography (PET) [PDF]

, 2017
The use of fluorine-18 as a radionuclide for positron emission tomography (PET) has become increasingly popular over the last two decades and cancer and neurology clinical centres worldwide are increasingly establishing competence in this modality for ...
David O’Hagan, Joshua Clark, O'Hagan, David, Clark, Joshua   +3 more
core   +1 more source

Fluorine-18 Labelled Radioligands for PET Imaging of Cyclooxygenase-2

Molecules, 2022
Molecular imaging probes enable the early and accurate detection of disease-specific biomarkers and facilitate personalized treatment of many chronic diseases, including cancer.
Jatinder Kaur, Atul Bhardwaj, Frank Wuest   +2 more
doaj   +1 more source