τBu₂SiF-Derivatized D₂-Receptor Ligands: The First SiFA-Containing Small Molecule Radiotracers for Target-Specific PET-Imaging [PDF]
, 2011 The synthesis, radiolabeling and in vitro evaluation of new silicon-fluoride acceptor (SiFA) derivatized D-2-receptor ligands is reported. The SiFA-technology simplifies the introduction of fluorine-18 into target specific biomolecules for Positron ...
Bartenstein, Peter +10 more
core +2 more sources
Dry Small Pleural Dissemination of Adenocarcinoma of the Lung Preoperatively Detected by PET/CT: A Report of Two Cases [PDF]
, 2008 Dry pleural dissemination in non-small cell lung cancer, defined as solid pleural metastasis of lung cancer without pleural eff usion, is a condition occurring in T4 lung cancer.
Aoe, Motoi +6 more
core +1 more source
, 2020 INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis.
Baguet, Tristan +12 more
core +1 more source
Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase [PDF]
, 2016 We thank EPSRC and the Scottish Imaging Network (SINAPSE) for grants. DO’H thanks the Royal Society for a Wolfson Research Merit Award and ST is grateful to the John and Kathleen Watson Scholarship for financial support.
Fleming, Ian N. +2 more
core +1 more source
ARAS: an automated radioactivity aliquoting system for dispensing solutions containing positron-emitting radioisotopes. [PDF]
, 2016 BackgroundAutomated protocols for measuring and dispensing solutions containing radioisotopes are essential not only for providing a safe environment for radiation workers but also to ensure accuracy of dispensed radioactivity and an efficient workflow ...
Carroll, Lewis +4 more
core +2 more sources
Radiosynthesis of [18F]-Labelled Pro-Nucleotides (ProTides)
Molecules, 2020 Phosphoramidate pro-nucleotides (ProTides) have revolutionized the field of anti-viral and anti-cancer nucleoside therapy, overcoming the major limitations of nucleoside therapies and achieving clinical and commercial success.
Alessandra Cavaliere +7 more
doaj +1 more source
Fluorine-18: an untapped resource in inorganic chemistry [PDF]
Chemical Communications, 2018 Advances in the field of fluorine chemistry have been applied extensively to the syntheses of 18F-labelled organic compounds and radiopharmaceuticals.
Cassis Varlow +4 more
openaire +2 more sources
Synthesis of [ 18 F]fluoroethoxy‐benzovesamicol, a radiotracer for cholinergic neurons [PDF]
, 1993 Full experimental details are given for the preparation of [ 18 F]fluoroethoxy‐benzovesamicol, (−)‐( 2R, 3R )‐ trans ‐2‐hydroxy‐3‐(4‐phenylpiperidino)‐5‐(2‐[ 18 F]fluoroethoxy)‐1,2,3,4‐tetralin, a new fluorine‐18 labeled cholinergic neuron mapping agent ...
Altar +31 more
core +1 more source
Synthesis, in vitro evaluation, and radiolabeling of fluorinated puromycin analogues: potential candidates for PET imaging of protein synthesis [PDF]
, 2016 There is currently no ideal radiotracer for imaging protein synthesis rate (PSR) by positron emission tomography (PET). Existing fluorine-18 labelled amino acid-based radiotracers predominantly visualize amino acid transporter processes, and in many ...
Alan C. Perkins +8 more
core +3 more sources
Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design
Frontiers in Chemistry, 2022 The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Yunze Wang +11 more
doaj +1 more source