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Fluorine-18 Labeling of Peptides and Proteins

2006
The pool of promising peptides worthy of investigation and evaluation for clinical use is continuously filled from different sources. Driven by the promising results obtained with peptides addressing somatostatin-2 receptor positive (sst2+) neuroendocrine tumours, other peptides targeting further receptor systems are being studied and evaluated ...
H J, Wester, M, Schottelius
openaire   +2 more sources

Fluorine-18 NaF PET imaging of child abuse

Pediatric Radiology, 2008
We describe the use of 18F-NaF positron emission tomography (PET) whole-body imaging for the evaluation of skeletal trauma in a case of suspected child abuse. To our knowledge, 18F NaF PET has not been used in the past for the evaluation of child abuse.
Laura A, Drubach   +3 more
openaire   +2 more sources

The half-life of fluorine-18

Journal of Inorganic and Nuclear Chemistry, 1964
Radiochemically pure 18F has been prepared by three different methods and its decay has been followed with β proportional counters and γ-ray counters in an effort to measure the half-life accurately. Analysis by a computer program that used the method of least squares gave a weighted mean half-life of 18F and a weighted standard deviation of the mean ...
J.D. Mahony, S.S. Markowitz
openaire   +1 more source

Fluorine-18 DOPA PET Imaging of Paraganglioma Syndrome

Clinical Nuclear Medicine, 2006
A 12-year-old boy was admitted after recently having had a resection performed of an extraadrenal retroperitoneal paraganglioma and left adrenalectomy for pheochromocytoma. Despite these procedures, the blood pressure and urinary noradrenalin were elevated.
Brink, Ingo   +3 more
openaire   +3 more sources

SPECT imaging of fluorine-18.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995
The objective of this work was to determine the potential clinical usefulness of SPECT to image 511-keV annihilation photons.A triple-headed gamma camera equipped with ultra-high-energy collimators was used to image 18F. Sensitivity measurements were carried out and the FWHM and FWTM were determined in air and for a unit-density scattering medium ...
P K, Leichner   +8 more
openaire   +1 more source

Cancer Imaging With Fluorine-18–Labeled Choline Derivatives

Seminars in Nuclear Medicine, 2007
The choline transporter and choline kinase enzyme frequently are overexpressed in malignancy. Therefore, positron-emitter-labeled compounds derived from choline have the potential to serve as oncologic probes for positron emission tomography. The fluorine-18 ((18)F)-labeled choline derivative fluorocholine (FCH) in particular has demonstrated potential
Sandi A, Kwee   +4 more
openaire   +2 more sources

Fluorine-18 labeling of proteins.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1987
Two fluorine-18-labeled reagents, methyl 3-[18F]fluoro-5-nitrobenzimidate and 4-[18F]fluorophenacyl bromide, have been prepared for covalent attachment of fluorine-18 to proteins. Both reagents can be prepared in moderate yields (30-50%, EOB) in synthesis times of 50-70 min.
M R, Kilbourn   +3 more
openaire   +1 more source

Fluorine-18 Fluorodeoxyglucose Uptake in the Retractile Testis

Clinical Nuclear Medicine, 1999
A 51-year-old man with a palpable mass in his right inguinal region had fluorine-18 fluorodeoxyglucose (F-18 FDG) whole-body positron emission tomography (PET) in our cancer screening program. FDG accumulated in the mass, suggesting a metabolically active lesion that was likely malignant.
H, Fujii   +5 more
openaire   +2 more sources

Synthesis of the fluorine-18 labeled inhalation anesthetics

Applied Radiation and Isotopes, 1994
Fourteen compounds (fluoroalkanes and fluoroethers), including the two most utilized inhalation anesthetics Isoflurane (CF3CHClOCF2H) and Halothane (CF3CHBrCl), have been labeled with fluorine-18 via a facile 18F-for-19F exchange reaction. The compounds include ten inhalation anesthetics which span a ten-fold range in potency and four structurally ...
M R, Satter   +4 more
openaire   +2 more sources

High Fluorine-18 Labeled Deoxyglucose Uptake in Sarcoidosis

Clinical Nuclear Medicine, 1996
A 72-year-old man underwent a whole-body fluorine-18 labeled deoxyglucose (FDG) PET study for cancer screening. On the PET images, multiple foci of intense FDG uptake were noted in the mediastinum. CT scan showed enlarged mediastinal nodes. Chest X-ray was normal. Mediastinoscopy and lymph node biopsy were performed.
S, Yasuda   +6 more
openaire   +2 more sources

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