Results 61 to 70 of about 3,321,367 (333)

Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18

Molecules, 2013
The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of novel and versatile bioorthogonal conjugation techniques especially for the radiolabeling of biologically ...
Doreen Pietzsch, Constantin Mamat, Marc Pretze   +2 more
doaj   +1 more source

Evaluation of Organo [¹⁸F]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers

Molecules, 2020
Fluorine-18 is the most widely used positron emission tomography (PET) radionuclide currently in clinical application, due to its optimal nuclear properties. The synthesis of 18F-labeled radiotracers often requires harsh reaction conditions, limiting the
Sofia Otaru, Surachet Imlimthan, Mirkka Sarparanta, Kerttuli Helariutta, Kristiina Wähälä, Anu J. Airaksinen   +5 more
doaj   +1 more source

Diagnostic accuracy of fluorine-18-fluorodeoxyglucose positron emission tomography in gallbladder cancer: A meta-analysis.

World Journal of Gastroenterology, 2015
AIM To meta-analyze published data about the diagnostic accuracy of fluorine-18-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) and PET/computed tomography (PET/CT) in the evaluation of primary tumor in patients with gallbladder cancer (
S. Annunziata, D. Pizzuto, C. Caldarella, F. Galiandro, R. Sadeghi, G. Treglia   +5 more
semanticscholar   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Crystal and molecular structure of potassium 18-crown-6-[2,6-bis(dimethylaminomethyl)phenyl]tin(IV) tetrafluoride

Main Group Metal Chemistry, 2011
The crystal structure of the title compound shows the [K(18-crown-6)]+ cation and [{2,6-(Me2NCH2)2C6H3}SnF4]– anion, which are held together through two potassium–fluorine and one potassium–tin electrostatic interaction.
Rotar Adina, Varga Richard A., Schürmann Markus, Silvestru Cristian, Jurkschat Klaus   +4 more
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Performance of Positron Emission Tomography and Positron Emission Tomography/Computed Tomography Using Fluorine-18-Fluorodeoxyglucose for the Diagnosis, Staging, and Recurrence Assessment of Bone Sarcoma

Medicine, 2015
To investigate the performance of fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) and PET/computed tomography (CT) in the diagnosis, staging, restaging, and recurrence surveillance of bone sarcoma by systematically reviewing ...
Fanxiao Liu, Qingyu Zhang, Dezhi Zhu, Zhenfeng Li, Jianmin Li, Boim Wang, Dongsheng Zhou, Jinlei Dong   +7 more
semanticscholar   +1 more source

A Scalable, Durable, Fire‐Safe All‐Day Passive Radiative Cooling Coating for Sustainable Buildings

Advanced Functional Materials, EarlyView.
This study reports a scalable, durable coating that combines a fire‑retardant copolymer adhesive, hollow glass microspheres, and boron oxide to achieve passive radiative cooling with over 94% solar reflectance and >95% mid‑infrared emissivity. The coating maintains performance after UV and rain exposure and exhibits UL‑94 V‑0 fire resistance, enabling ...
Zhewen Ma, Yuanhao Feng, Alex Y. Song, Toan Dinh, Min Hong, John Bell, Boyou Hou, Pingan Song, Wei Zheng   +8 more
wiley   +1 more source

Synthesis and validation of [18F]mBPET-1, a fluorine-18 labelled mTOR inhibitor derivative based on a benzofuran backbone

EJNMMI Radiopharmacy and Chemistry, 2020
Background Targeted therapy of HER2 positive breast cancer has led to clinical success in some cases with primary and secondary resistance being major obstacles.
Christian W. Wichmann, Yit Wooi Goh, Adam C. Parslow, Angela Rigopoulos, Nancy Guo, Andrew M. Scott, Uwe Ackermann, Jonathan M. White   +7 more
doaj   +1 more source

Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18

Scientific Reports, 2015
Positron emission tomography (PET) is unique in that it allows quantification of biochemical processes in vivo, but difficulties with preparing suitably labelled radiotracers limit its scientific and diagnostic applications. Aromatic [18F]fluorination of
K. Sander, Thibault Gendron, E. Yiannaki, Klaudia A. Cybulska, T. Kalber, M. Lythgoe, E. Årstad   +6 more
semanticscholar   +1 more source