Results 51 to 60 of about 4,674,317 (310)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

A BORON COMPLEX DESIGNED FOR FLUORINE-18 LABELING AIMING FOR PET IMAGING APPLICATION

Hematology, Transfusion and Cell Therapy
Introduction/Justification: Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide due to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals.
Mariana Almeida Figueira, Joaldo Garcia Arruda, Victor Maia Miranda, Pedro Paulo Corbi, Luiz Antônio Sodré Costa, Fabio Luiz Navarro Marques, Victor Marcelo Deflon   +6 more
doaj   +1 more source

Elemental fluorine as a valid synthetic reagent [PDF]

, 1994
Chapter I Chapter I reviews the uses of elemental fluorine in selective organic synthesis and its use in the generation of selective electrophilic fluorinating agents.
Skinner, Christopher John
core  

Enhancing Low‐Temperature Performance of Sodium‐Ion Batteries via Anion‐Solvent Interactions

Advanced Functional Materials, EarlyView.
DOL is introduced into electrolytes as a co‐solvent, increasing slat solubility, ion conductivity, and the de‐solvent process, and forming an anion‐rich solvent shell due to its high interaction with anion. With the above virtues, the batteries using this electrolyte exhibit excellent cycling stability at low temperatures. Abstract Sodium‐ion batteries
Cheng Zheng, Qian Yao, Yanan Sun, Hongyu Lv, Zhongchao Bai, Guoliang Zhang, Nana Wang, Jian Yang   +7 more
wiley   +1 more source

Synthesis and evaluation of TSPO-targeting radioligand [18F]F-TFQC for PET neuroimaging in epileptic rats

Acta Pharmaceutica Sinica B
The translocator protein (TSPO) positron emission tomography (PET) can noninvasively detect neuroinflammation associated with epileptogenesis and epilepsy.
Wenhui Fu, Qingyu Lin, Zhequan Fu, Tingting Yang, Dai Shi, Pengcheng Ma, Hongxing Su, Yunze Wang, Guobing Liu, Jing Ding, Hongcheng Shi, Dengfeng Cheng   +11 more
doaj   +1 more source

2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET—Synthesis, Triage, and Radiolabeling

Molecules, 2018
Cyclooxygenase 2 (COX-2) is an inducible enzyme responsible for the conversion of arachidonic acid into the prostaglandins, PGG2 and PGH2. Expression of this enzyme increases in inflammation.
Michelle Y. Cortes-Salva, Stal Shrestha, Prachi Singh, Cheryl L. Morse, Kimberly J. Jenko, Jose A. Montero Santamaria, Sami S. Zoghbi, Robert B. Innis, Victor W. Pike   +8 more
doaj   +1 more source

Chemical diffusion of fluorine in jadeite melt at high pressure [PDF]

, 1984
The chemical diffusion of fluorine in jadeite melt has been investigated from 10 to 15 kbars and 1200 to 1400°C using diffusion couples of Jadeite melt and fluorine-bearing jadeite melt (6.3 wt.% F). The diffusion profile data indicate that the diffusion
Scarfe, Christopher M., Dingwell, Donald B.   +1 more
core   +1 more source

Can fluorine form triple bonds? [PDF]

, 2022
A central dogma is that fluorine is the most electro negative element in the PSE and would thusact as a pure electron acceptor. However, to some chemists it is known, that fluorine can bond induality.
Julian M., Kleber
core   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

Advanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero, Meghna Jha, Elsa Veronica Flores‐Vela, Joost Kimpel, Andreas Schaefer, Jiali Guo, Jesika Asatryan, Alberto Peinador Veiga, Shuichi Haraguchi, Per‐Anders Carlsson, Jaime Martín, Mariano Campoy‐Quiles, Christian Müller   +12 more
wiley   +1 more source