Results 71 to 80 of about 53,359 (237)

Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18

Molecules, 2013
The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of novel and versatile bioorthogonal conjugation techniques especially for the radiolabeling of biologically ...
Doreen Pietzsch, Constantin Mamat, Marc Pretze   +2 more
doaj   +1 more source

Design Optimization of Enriched Water Targets [PDF]

, 2004
The purpose of this research project is to design and optimize the enriched water targets used in the cyclotron systems that are manufactured by CTI Inc. Enriched water target is the source of Fluorine 18 that is used in the Positron Emission Tomography (
Kandala, Sampath Telikicherla
core   +1 more source

Solitary Asymptomatic Thyroid Metastasis from Hepatocellular Carcinoma Detected by FDG-PET/CT [PDF]

, 2010
Thyroid metastases from hepatocellular carcinoma (HCC) seldom occur and are often difficult to diagnose because of their asymptomatic clinical course.
Abe, Koichiro, Fukuhara, Takasuke, Maehara, Yoshihiko, Mano, Youhei, Maruoka, Yasuhiro, Morita, Kazutoyo, Motomura, Takashi, Shirabe, Ken, Sugimachi, Keishi, Tajima, Tsuyoshi, Takeishi, Kazuki, Taketomi, Akinobu, Toshima, Takeo   +12 more
core   +3 more sources

Crystal and molecular structure of potassium 18-crown-6-[2,6-bis(dimethylaminomethyl)phenyl]tin(IV) tetrafluoride

Main Group Metal Chemistry, 2011
The crystal structure of the title compound shows the [K(18-crown-6)]+ cation and [{2,6-(Me2NCH2)2C6H3}SnF4]– anion, which are held together through two potassium–fluorine and one potassium–tin electrostatic interaction.
Rotar Adina, Varga Richard A., Schürmann Markus, Silvestru Cristian, Jurkschat Klaus   +4 more
doaj   +1 more source

In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography [PDF]

, 2008
The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor ...
Bergstr  m, Burns, Chou, D. A. Harki, D. B. Stout, Dervan, Dervan, Dudouet, Edelson, Gross, Harapanhalli, Hsu, K  hnast, Lee, Lendvai, M. E. Phelps, N. Satyamurthy, P. B. Dervan, Phelps, Phelps, Poethko, Puckett, Roivainen, Schottelius, Tavitian, Toyokuni, Trauger   +26 more
core   +3 more sources

Synthesis and validation of [18F]mBPET-1, a fluorine-18 labelled mTOR inhibitor derivative based on a benzofuran backbone

EJNMMI Radiopharmacy and Chemistry, 2020
Background Targeted therapy of HER2 positive breast cancer has led to clinical success in some cases with primary and secondary resistance being major obstacles.
Christian W. Wichmann, Yit Wooi Goh, Adam C. Parslow, Angela Rigopoulos, Nancy Guo, Andrew M. Scott, Uwe Ackermann, Jonathan M. White   +7 more
doaj   +1 more source

Initial Evaluation of AF78: a Rationally Designed Fluorine-18-Labelled PET Radiotracer Targeting Norepinephrine Transporter [PDF]

, 2019
Purpose Taking full advantage of positron emission tomography (PET) technology, fluorine-18-labelled radiotracers targeting norepinephrine transporter (NET) have potential applications in the diagnosis and assessment of cardiac sympathetic nerve ...
Chen, Xinyu, Decker, Michael, Fritz, Alexander, Higuchi, Takahiro, Kimura, Hiroyuki, Koshino, Kazuhiro, Nose, Naoko, Rowe, Steven P., Werner, Rudolf A., Yagi, Yusuke   +9 more
core   +1 more source

Dry Small Pleural Dissemination of Adenocarcinoma of the Lung Preoperatively Detected by PET/CT: A Report of Two Cases [PDF]

, 2008
Dry pleural dissemination in non-small cell lung cancer, defined as solid pleural metastasis of lung cancer without pleural eff usion, is a condition occurring in T4 lung cancer.
Aoe, Motoi, Date, Hiroshi, Okutani, Daisuke, Oto, Takahiro, Sano, Yoshifumi, Toyooka, Shinichi, Yamane, Masaomi   +6 more
core   +1 more source

Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain

Pharmaceuticals, 2016
Phosphodiesterases (PDEs) are enzymes that play a major role in cell signalling by hydrolysing the secondary messengers cyclic adenosine monophosphate (cAMP) and/or cyclic guanosine monophosphate (cGMP) throughout the body and brain.
Jianrong Liu, Barbara Wenzel, Sladjana Dukic-Stefanovic, Rodrigo Teodoro, Friedrich-Alexander Ludwig, Winnie Deuther-Conrad, Susann Schröder, Jean-Michel Chezal, Emmanuel Moreau, Peter Brust, Aurélie Maisonial-Besset   +10 more
doaj   +1 more source

Novel [18F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules

EJNMMI Radiopharmacy and Chemistry, 2022
Background Prosthetic approach for the radiolabeling of biologics with fluorine-18 is a robust strategy and has been employed for many years. It requires fast, biocompatible and selective reactions suited to these fragile molecules. Michael addition of a
Mylène Richard, Françoise Hinnen, Bertrand Kuhnast   +2 more
doaj   +1 more source