Results 81 to 90 of about 41,523 (233)

Combined Evaluation of FDG-PET and MRI Improves Detection and Differentiation of Dementia [PDF]

, 2011
INTRODUCTION: Various biomarkers have been reported in recent literature regarding imaging abnormalities in different types of dementia. These biomarkers have helped to significantly improve early detection and also differentiation of various dementia ...
Barthel, Henryk, Dukart, Juergen, Horstmann, Annette, Mueller, Karsten, Möller, Harald E., Sabri, Osama, Schroeter, Matthias L., Villringer, Arno   +7 more
core   +4 more sources

Relationships Between Brain Glucose Metabolism Patterns and Impaired Glycemic Status: A Systematic Review of FDG‐PET Studies With a Focus on Alzheimer's Disease

Human Brain Mapping, Volume 46, Issue 4, March 2025.
Insulin resistance can lead to neuronal damage and cerebral hypometabolism through different mechanisms including mitochondrial dysfunction, impairment of cerebral blood vessel function. In addition, insulin resistance is linked to amyloid and tau accumulation and neuroinflammation, the key mechanisms involved in Alzheimer disease and neuronal damage ...
Setareh Soltani, Mahsa Dolatshahi, Sara Soltani, Kian Khazaei, Maryam Rahmani, Cyrus A. Raji   +5 more
wiley   +1 more source

Prognostic Value of Volume-Based Positron Emission Tomography/Computed Tomography in Patients With Nasopharyngeal Carcinoma Treated With Concurrent Chemoradiotherapy [PDF]

Clinical and Experimental Otorhinolaryngology, 2015
ObjectivesThe aim of this study was to evaluate the prognostic value of volume-based metabolic parameters measured by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in patients with nasopharyngeal carcinoma (NPC).MethodsForty-four NPC ...
Seung Hwan Moon, Joon Young Choi, Hwan Joo Lee, Young-Ik Son, Chung-Hwan Baek, Yong Chan Ahn, Myung-Ju Ahn, Keunchil Park, Byung-Tae Kim   +8 more
doaj   +1 more source

Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients. [PDF]

, 2014
BackgroundGender-based differences in disease onset in murine models of malignant peripheral nerve sheath tumor (MPNST) and in patients with Neurofibromatosis type-1-(NF-1)-associated or spontaneous MPNST has not been well studied.MethodsForty-three ...
Dry, Sarah M, Eilber, Fritz C, Federman, Noah, Li, Yunfeng, Nakashima, Jonathan, Shurell, Elizabeth, Smith, Kathleen B, Tam, Brenna M, Tap, William D, Tran, Linh M, Wu, Hong   +10 more
core   +2 more sources

The Common Alzheimer's Disease Research Ontology (CADRO) for biomarker categorization

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 1, January-March 2025.
Abstract Biomarkers are vital to Alzheimer's disease (AD) drug development and clinical trials, and will have an increasing role in clinical care. In this narrative review, we demonstrate the use of the National Institutes on Aging/Alzheimer's Association (NIA/AA) Common Alzheimer's Disease Research Ontology (CADRO) system for the categorization of ...
Amanda M. Leisgang Osse, Jefferson W. Kinney, Jeffrey L. Cummings   +2 more
wiley   +1 more source

The positron emission tomography with F18 17β-estradiol has the potential to benefit diagnosis and treatment of endometrial cancer [PDF]

, 2007
Background. The positron emission tomography (PET) with F18 17β-estradiol (FES) has good imaging for assessment of estrogen receptor in breast cancer. Case.
59650, 59651, 59652, 59653, 59654, 59655, 59656, FUJIBAYASHI, Yasuhisa, KOTSUJI, Fumikazu, KUROKAWA, Tetsuji, OKAZAWA, Hidehiko, SAWAMURA, Yoko, SHINAGAWA, Akiko, YOSHIDA, Yoshio   +13 more
core   +1 more source

Tumor‐Associated Carbohydrate Antigen 19–9 (CA 19–9), a Promising Target for Antibody‐Based Detection, Diagnosis, and Immunotherapy of Cancer

ChemMedChem, Volume 19, Issue 24, December 16, 2024.
Carbohydrate antigen 19–9 (CA 19–9), also known as sialyl Lewis A, is a tetrasaccharide overexpressed on a wide range of cancerous cells, most prominently pancreatic ductal adenocarcinoma. The review discusses the synthesis of CA 19–9, elicitation of antibodies through vaccination, development of anti‐CA 19–9 monoclonal antibodies, and their ...
Athar Nakisa, Lorenzo F. Sempere, Xi Chen, Linda T. Qu, Daniel Woldring, Howard C. Crawford, Xuefei Huang   +6 more
wiley   +1 more source

The Relationship Between KRAS Mutation and 18F-FDG Uptake Parameters in Colorectal Cancer

Bagcilar Medical Bulletin, 2022
Objective:Our purpose in this study was to evaluate whether Kirsten rat sarcoma viral oncogene (KRAS) exon-2 mutation affected 18F-fluorodeoxyglucose (FDG) accumulation patterns, total lesion glycolysis and metabolic tumor volume in colorectal cancer ...
Aynur Özen, Serkan Menekşe, Esat Namal, Aslı Kahraman Akkalp, Merve Tokoçin, Talar Vartanoğlu, Emel Gökmen, Fatih Çelebi   +7 more
doaj   +1 more source

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. [PDF]

, 2016
BackgroundMalignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade.
Bernthal, Nicholas, Chmielowski, Bartosz, Crompton, Joseph G, Dry, Sarah, Eilber, Fritz C, Federman, Noah, Jensen, Sarah, Li, Yunfeng, Nelson, Scott, Shurell, Elizabeth, Singh, Arun S, Tumeh, Paul   +11 more
core   +2 more sources

The status of MRI databases across the world focused on psychiatric and neurological disorders

Psychiatry and Clinical Neurosciences, Volume 78, Issue 10, Page 563-579, October 2024.
Neuroimaging databases for neuro‐psychiatric disorders enable researchers to implement data‐driven research approaches by providing access to rich data that can be used to study disease, build and validate machine learning models, and even redefine disease spectra.
Saori C. Tanaka, Kiyoto Kasai, Yasumasa Okamoto, Shinsuke Koike, Takuya Hayashi, Ayumu Yamashita, Okito Yamashita, Tom Johnstone, Franco Pestilli, Kenji Doya, Go Okada, Hotaka Shinzato, Eri Itai, Yuji Takahara, Akihiro Takamiya, Motoaki Nakamura, Takashi Itahashi, Ryuta Aoki, Yukiaki Koizumi, Masaaki Shimizu, Jun Miyata, Shuraku Son, Morio Aki, Naohiro Okada, Susumu Morita, Nobukatsu Sawamoto, Mitsunari Abe, Yuki Oi, Kazuaki Sajima, Koji Kamagata, Masakazu Hirose, Yohei Aoshima, Sayo Hamatani, Nobuhiro Nohara, Misako Funaba, Tomomi Noda, Kana Inoue, Jinichi Hirano, Masaru Mimura, Hidehiko Takahashi, Nobutaka Hattori, Atsushi Sekiguchi, Mitsuo Kawato, Takashi Hanakawa   +43 more
wiley   +1 more source