Objective: F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) has been increasingly used in myocardial viability imaging. In routine PET viability studies, oral glucose and intravenous insulin loading is commonly utilized.
Ismet Sarikaya+4 more
doaj +1 more source
Insulin resistance can lead to neuronal damage and cerebral hypometabolism through different mechanisms including mitochondrial dysfunction, impairment of cerebral blood vessel function. In addition, insulin resistance is linked to amyloid and tau accumulation and neuroinflammation, the key mechanisms involved in Alzheimer disease and neuronal damage ...
Setareh Soltani+5 more
wiley +1 more source
Background We performed a systematic review and meta-analysis to evaluate the prognostic significance of 18F-FDG PET and PET/CT for evaluation of responses to neoadjuvant chemotherapy (NAC) in breast cancer patients.
Sangwon Han, Joon Young Choi
doaj +1 more source
Prognostic Value of Volume-Based Positron Emission Tomography/Computed Tomography in Patients With Nasopharyngeal Carcinoma Treated With Concurrent Chemoradiotherapy [PDF]
ObjectivesThe aim of this study was to evaluate the prognostic value of volume-based metabolic parameters measured by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in patients with nasopharyngeal carcinoma (NPC).MethodsForty-four NPC ...
Seung Hwan Moon+8 more
doaj +1 more source
The Common Alzheimer's Disease Research Ontology (CADRO) for biomarker categorization
Abstract Biomarkers are vital to Alzheimer's disease (AD) drug development and clinical trials, and will have an increasing role in clinical care. In this narrative review, we demonstrate the use of the National Institutes on Aging/Alzheimer's Association (NIA/AA) Common Alzheimer's Disease Research Ontology (CADRO) system for the categorization of ...
Amanda M. Leisgang Osse+2 more
wiley +1 more source
The Relationship Between KRAS Mutation and 18F-FDG Uptake Parameters in Colorectal Cancer
Objective:Our purpose in this study was to evaluate whether Kirsten rat sarcoma viral oncogene (KRAS) exon-2 mutation affected 18F-fluorodeoxyglucose (FDG) accumulation patterns, total lesion glycolysis and metabolic tumor volume in colorectal cancer ...
Aynur Özen+7 more
doaj +1 more source
[F18] FDG-PET/CT for manual or semiautomated GTV delineation of the primary tumor for radiation therapy planning in patients with esophageal cancer: is it useful? [PDF]
BACKGROUND Target volume definition of the primary tumor in esophageal cancer is usually based on computed tomography (CT) supported by endoscopy and/or endoscopic ultrasound and can be difficult given the low soft-tissue contrast of CT resulting in ...
Andrae, Claudia+8 more
core +1 more source
Carbohydrate antigen 19–9 (CA 19–9), also known as sialyl Lewis A, is a tetrasaccharide overexpressed on a wide range of cancerous cells, most prominently pancreatic ductal adenocarcinoma. The review discusses the synthesis of CA 19–9, elicitation of antibodies through vaccination, development of anti‐CA 19–9 monoclonal antibodies, and their ...
Athar Nakisa+6 more
wiley +1 more source
Clinical Etiology of Hypermetabolic Pelvic Lesions in Postoperative Positron Emission Tomography/Computed Tomography for Patients With Rectal and Sigmoid Cancer [PDF]
Purpose The purpose of this study was to present various clinical etiologies of hypermetabolic pelvic lesions on postoperative positron emission tomography/computed tomography (PET/CT) images for patients with rectal and sigmoid cancer.
Yun Hee Kang, Eunji Han, Geon Park
doaj +1 more source
The status of MRI databases across the world focused on psychiatric and neurological disorders
Neuroimaging databases for neuro‐psychiatric disorders enable researchers to implement data‐driven research approaches by providing access to rich data that can be used to study disease, build and validate machine learning models, and even redefine disease spectra.
Saori C. Tanaka+43 more
wiley +1 more source