Results 81 to 90 of about 42,994 (239)

An Excellent Clinical and Radiological Response Pattern to Pembrolizumab in a Patient With Metastatic Adrenocortical Carcinoma and Lynch Syndrome

open access: yesIJU Case Reports, Volume 8, Issue 4, Page 361-364, July 2025.
ABSTRACT Introduction The prognosis of unresectable metastatic adrenocortical carcinoma is very poor. We report a case of Lynch syndrome accompanying metastatic adrenocortical carcinoma treated with pembrolizumab. Case Presentation A 73‐year‐old woman was diagnosed with left adrenocortical carcinoma and multiple lung, liver, and lymph node metastases ...
Yuki Shimozawa   +9 more
wiley   +1 more source

Role of integrated F-18 fluoro-deoxy-glucose positron emission tomography and computed tomography in evaluation of lung cancer [PDF]

open access: yesArchive of Oncology, 2012
Lung cancer is one of the leading causes of death in the world. It is generally divided in two groups: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).
Šobić-Šaranović Dragana
doaj   +1 more source

Relationships Between Brain Glucose Metabolism Patterns and Impaired Glycemic Status: A Systematic Review of FDG‐PET Studies With a Focus on Alzheimer's Disease

open access: yesHuman Brain Mapping, Volume 46, Issue 4, March 2025.
Insulin resistance can lead to neuronal damage and cerebral hypometabolism through different mechanisms including mitochondrial dysfunction, impairment of cerebral blood vessel function. In addition, insulin resistance is linked to amyloid and tau accumulation and neuroinflammation, the key mechanisms involved in Alzheimer disease and neuronal damage ...
Setareh Soltani   +5 more
wiley   +1 more source

The Common Alzheimer's Disease Research Ontology (CADRO) for biomarker categorization

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 11, Issue 1, January-March 2025.
Abstract Biomarkers are vital to Alzheimer's disease (AD) drug development and clinical trials, and will have an increasing role in clinical care. In this narrative review, we demonstrate the use of the National Institutes on Aging/Alzheimer's Association (NIA/AA) Common Alzheimer's Disease Research Ontology (CADRO) system for the categorization of ...
Amanda M. Leisgang Osse   +2 more
wiley   +1 more source

Status of F-18 fluorodeoxyglucose uptake in normal and hibernating myocardium after glucose and insulin loading

open access: yesJournal of the Saudi Heart Association, 2018
Objective: F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) has been increasingly used in myocardial viability imaging. In routine PET viability studies, oral glucose and intravenous insulin loading is commonly utilized.
Ismet Sarikaya   +4 more
doaj   +1 more source

Tumor‐Associated Carbohydrate Antigen 19–9 (CA 19–9), a Promising Target for Antibody‐Based Detection, Diagnosis, and Immunotherapy of Cancer

open access: yesChemMedChem, Volume 19, Issue 24, December 16, 2024.
Carbohydrate antigen 19–9 (CA 19–9), also known as sialyl Lewis A, is a tetrasaccharide overexpressed on a wide range of cancerous cells, most prominently pancreatic ductal adenocarcinoma. The review discusses the synthesis of CA 19–9, elicitation of antibodies through vaccination, development of anti‐CA 19–9 monoclonal antibodies, and their ...
Athar Nakisa   +6 more
wiley   +1 more source

Clinical Etiology of Hypermetabolic Pelvic Lesions in Postoperative Positron Emission Tomography/Computed Tomography for Patients With Rectal and Sigmoid Cancer [PDF]

open access: yesAnnals of Coloproctology, 2018
Purpose The purpose of this study was to present various clinical etiologies of hypermetabolic pelvic lesions on postoperative positron emission tomography/computed tomography (PET/CT) images for patients with rectal and sigmoid cancer.
Yun Hee Kang, Eunji Han, Geon Park
doaj   +1 more source

The status of MRI databases across the world focused on psychiatric and neurological disorders

open access: yesPsychiatry and Clinical Neurosciences, Volume 78, Issue 10, Page 563-579, October 2024.
Neuroimaging databases for neuro‐psychiatric disorders enable researchers to implement data‐driven research approaches by providing access to rich data that can be used to study disease, build and validate machine learning models, and even redefine disease spectra.
Saori C. Tanaka   +43 more
wiley   +1 more source

Prognostic value of 18F-FDG PET and PET/CT for assessment of treatment response to neoadjuvant chemotherapy in breast cancer: a systematic review and meta-analysis

open access: yesBreast Cancer Research, 2020
Background We performed a systematic review and meta-analysis to evaluate the prognostic significance of 18F-FDG PET and PET/CT for evaluation of responses to neoadjuvant chemotherapy (NAC) in breast cancer patients.
Sangwon Han, Joon Young Choi
doaj   +1 more source

Hybrid Imaging in Head and Neck Sarcoidosis [PDF]

open access: yes, 2019
To determine the prevalence of head and neck sarcoidosis (HNS) and evaluate the role of hybrid molecular imaging in HNS. Between 2010 and 2018, 222 patients with chronic sarcoidosis and presence of prolonged symptoms of active disease were referred to ...
Artiko, Vera M.   +4 more
core   +1 more source

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