Results 1 to 10 of about 17,962 (220)
Tagged and untagged amyloid precursor protein E2 domain have comparable thermal stability and metal-ion binding propensity [PDF]
BMC Research NotesObjective The amyloid precursor protein, central to the pathology of several disease including Alzheimer’s disease, cancer and obesity, represents a therapeutic target.
Zamaxasibe Nxele +4 more
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A simple, reliable and easily generalizable cell-based assay for screening potential drugs that inhibit lipid accumulation [PDF]
Current Research in ToxicologyEctopic lipid deposition in the hepatocyte plays an important role in the development of nonalcoholic fatty liver disease (NAFLD), which has become one of the most common causes of chronic liver disease worldwide yet no approved drugs are currently ...
Weili Yang +4 more
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Validation and standardization of a fluorometric method for alpha glucosidase activity assay in the detection of Pompe disease [PDF]
Reviews in Clinical Medicine, 2023 Introduction: Pompe Disease is a type of lysosomal storage disease that is caused by a deficiency of the lysosomal alpha glucosidase. Pompe disease, as a multi-systemic disorder has a broad spectrum of clinical symptoms.
Armin Mokhtariye +4 more
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eLife, 2022 Acid-sensing ion channels (ASICs) are trimeric proton-gated cation channels involved in fast synaptic transmission. Pharmacological inhibition of ASIC1a reduces neurotoxicity and stroke infarct volumes, with the cysteine knot toxin psalmotoxin-1 (PcTx1 ...
Stephanie A Heusser +3 more
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Aggregate, 2022 Probing the onset of micellization, or determining the critical micelle concentration (CMC), is of crucial importance while remains to be challenged by growing demand for extraordinary sensitivity and accuracy.
Haisheng He +8 more
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BioTechniques, 2022 Agarose gel electrophoresis is a relatively easy to use method, commonly applied to evaluate PCR reaction success. Intercalating agents or dyes are used to visualize the amplified fragments. However, it is uncertain to what extent the brightness of bands
Patrick Wittmeier, Susanne Hummel
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The Activity of NADP(H) Oxidoreductase of Elicitated Cell Culture of Cinchona ledgeriana Moens
Jurnal Ilmu Pertanian Indonesia, 2020 Cinchona ledgeriana Moens is an industrial plant producing secondary metabolite quinoline alkaloids. To maintain and moreover, to increase the quinoline production especially quinine, in vitro culture system through cell culture could be a potential ...
Maulidiyah Utami +3 more
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Atmospheric nitrogen deposition and canopy retention influences on photosynthetic performance at two high nitrogen deposition Swiss forests [PDF]
Tellus: Series B, Chemical and Physical Meteorology, 2012 Portable chlorophyll fluorometry measurements, providing plant photosynthetic efficiency (PE) data, were carried out at two contrasting Swiss forests experiencing high nitrogen (N) deposition. Fluorometry data were obtained in conjunction with controlled
E. Wortman +7 more
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Frontiers in Remote Sensing, 2022 Chlorophyll-a is an essential climate variable. Chlorophyll-a in situ measurements are usually used for the validation of satellite images. Previous intercomparisons have shown that there can be substantial differences between in situ laboratories.
Susanne Kratzer +3 more
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Frontiers in Physiology, 2021 Coral reefs are declining worldwide due to global changes in the marine environment. The increasing frequency of massive bleaching events in the tropics is highlighting the need to better understand the stages of coral physiological responses to extreme ...
Walter Dellisanti +10 more
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