Results 111 to 120 of about 132,194 (344)

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types. [PDF]

, 2018
Understanding the distribution patterns of antibiotics at the site of infection is paramount to selecting adequate drug regimens and developing new antibiotics.
Blanc, Landry, Chen, Pei-Yu, Dartois, Véronique, Daudelin, Isaac B, Martinot, Amanda J, Podell, Brendan K, Prideaux, Brendan, Savic, Rada M, Zimmerman, Matthew   +8 more
core   +2 more sources

Mallotus philippensis Extract‐Infused Locust Bean Gum‐Based Ternary Hydrogel: A Green Fabrication Approach for the Controlled Release of Levofloxacin

Macromolecular Bioscience, EarlyView.
A novel bio‐based hydrogel was developed using Mallotus philippensis extract, Lucast bean gum, and chitosan for controlled levofloxacin release. The hydrogel exhibited excellent swelling behavior, antimicrobial activity, and pH‐responsive drug release, demonstrating its potential for advanced wound healing and targeted drug delivery applications ...
Sehrish Jabeen, Atif Islam, Rafi Ullah Khan, Dirk W. Schubert   +3 more
wiley   +1 more source

Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017 [PDF]

, 2018
Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms.
Aghdassi, S., Alberg, T., Arendt, V., Arvaniti, K., Asensio, A., Berg, T. C., Berger-Carbonne, A., Borg, M. A., Bosnjak, Z., Budimir, A., Burns, K., Cairns, S., Cantero, M., Daniau, C., Debacker, M., Deptula, A., Dimina, E., Dobreva, E., Dragovac, G., Florentin, D., Gastmeier, P., Gibbons, C., Gudlaugsson, O., Hadjihannas, L., Hajdu, A., Hansen, S., Harrison, W., Hopkins, S., Hopmans, T., Hristova, R., Ivanov, I. N., Jindrak, V., Johnson, A., Karki, T., Kinross, P., Kontopidou, F., Korosec, A., Latour, K., Litvova, S., Lyytikainen, O., Markovic-Denic, L., Martin, P., McConaghy, M., Mitt, P., Monnet, D. L., Moro, M. L., Nedyalkov, M., Neves, I., Niculcea, A. S., Pacheco, P., Plachouras, D., Presterl, E., Quattrocolo, F., Reilly, J., Rydygier, L., Sartaj, M., Sarvikivi, E., Serban, R. I., Smid, E., Staniulyte, J., Stefkovicova, M., Strauss, R., Suetens, C., Vandael, E., Vilde, A., Weist, K., Zarb, P., Zingg, W., Zotti, C. M., Zupanc, T. L.   +69 more
core   +7 more sources

Chloromethane‐Enabled Quaternization of Linear Polyglycerol Amines and Their Application as Antibacterial Agents

Macromolecular Rapid Communications, EarlyView.
This study details a scalable process for synthesizing quaternary ammonium compounds (QACs) from linear polyglycerols using gaseous chloromethane. The resulting compounds demonstrate effective antibacterial and antibiofilm properties against drug‐resistant S.
Natalie Hanheiser, Merlin Kleoff, Katharina Achazi, Abhishek Singh, Sebastian Riedel, Rainer Haag   +5 more
wiley   +1 more source

To compare the in vitro activity of 3 popular fluoroquinolones against common respiratory and middle ear pathogens

Bengal Journal of Otolaryngology and Head Neck Surgery, 2013
Antibiotic resistance among respiratory tract pathogens is increasing worldwide. Beta-lactam-resistant as well as macrolide and fluoroquinolone-resistant strains of the commonest pathogens  are being isolated with increasing frequency in manycountries .
Soma Sarkar, Manideepa Sengupta, Puranjay Saha, Soumyabrata Nag   +3 more
doaj  

Rational use of the fluoroquinolones

South African Medical Journal, 2019
The systemic fluoroquinolones (FQs) have recently been reported to be associated with significant side-effects in susceptible individuals. This has prompted the Food and Drug Administration (FDA) in the USA and the European Medicines Agency (EMA) to issue warnings regarding their use.
Richards, G A, Brink, A J, Feldman, C
openaire   +3 more sources

Risk of acute kidney injury associated with the use of fluoroquinolones

Canadian Medical Association Journal, 2013
Background: Case reports indicate that the use of fluoroquinolones may lead to acute kidney injury. We studied the association between the use of oral fluoroquinolones and acute kidney injury, and we examined interaction with renin–angiotensin-system ...
Steven T. Bird, M. Etminan, J. Brophy, A. Hartzema, J. A. Delaney   +4 more
semanticscholar   +1 more source

Lupeol as a Potential Inhibitor of NorA Efflux Pumps in Staphylococcus aureus: In Silico and In Vitro Evidence

ChemistryOpen, EarlyView.
Antimicrobial resistance remains one of the major challenges to global public health, compromising the effectiveness of treatments and contributing to increased morbidity and mortality associated with bacterial infections. Among the mechanisms involved, efflux pumps—such as NorA, expressed in resistant strains of Staphylococcus aureus—are particularly ...
Nara Juliana Santos Araújo, Camila Aparecida Pereira Silva, Vanessa Lima Bezerra, Cicera Datiane Morais Oliveira‐Tintino, Gabriel Gonçalves de Alencar, Maria do Socorro Costa, Ana Raquel Pereira da Silva, Josefa Sayonara dos Santos, Kamila Correa Camara, Heberty diTarso Fernandes Facundo, Lívia Pereira Ferreira, Henrique Douglas Melo Coutinho, José Maria Barbosa Filho, Carolina Bandeira Domiciano, José Bezerra de Araújo‐Neto, Jacqueline Cosmo Andrade‐Pinheiro.   +15 more
wiley   +1 more source

Comparative Photo‐Induced Aging of Poly(Butylene Adipate‐co‐Terephthalate) and Polystyrene Microplastics and their Divergent Affinities for Tetracycline in Aquatic Environments

ChemistryOpen, EarlyView.
UV‐water aging endows biodegradable poly (butylene adipate‐co‐terephthalate) (PBAT), unlike polystyrene, with abundant polar groups that markedly enhance its interaction with tetracycline and subsequent sorption, highlighting distinct antibiotic retention and release behavior for biodegradable versus conventional microplastics.
Sadam Hussain Tumrani, Zeenat Naz, Razium Ali Soomro, Mohamed E. Khalifa, Gaber A. M. Mersal, Ahmed M. Fallatah, Selcan Karakuş   +6 more
wiley   +1 more source

SOS Response Induces Persistence to Fluoroquinolones in Escherichia coli

PLoS Genetics, 2009
Bacteria can survive antibiotic treatment without acquiring heritable antibiotic resistance. We investigated persistence to the fluoroquinolone ciprofloxacin in Escherichia coli.
Tobias Dörr, K. Lewis, M. Vulić
semanticscholar   +1 more source