Results 111 to 120 of about 64,835 (235)

Biodegradation mechanism of typical fluoroquinolones in sewage-sludge composts

, 2021
Jun Zhang, Yulan Lü, Qinying Yan, Hongtao Liu, Beidou Xi, Dunqiu Wang   +5 more
openalex   +1 more source

Double‐Duty Drugs: Repositioning Antipsychotics to Combat Bacterial Infections

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Antipsychotics can exert antibacterial effects via several mechanisms: (1, 2) Due to their amphiphilic and cationic characteristics, antipsychotics can negatively affect the integrity of the plasma membrane by disrupting its structure and electrochemical potential.
Navid Faraji, Mohammad Abavisani, Negar Ebadpour, Sercan Karav, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon, Victoria R. Wong, Samuelson E. Osifo, Timothy Edwards, Himanshu Rao, Jewelia Rempuszewski, Andrew J. Frear, Shaan Sadhwani, Neel B. Shah, Kenneth L. Urish   +9 more
wiley   +1 more source

Ciprofloxacin Treatment in Juvenile Mice Involves Neuronal Activation and Mimics Physical Features of Human Disease

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Tendinopathy is a complex, painful condition that affects up to 5% of the general population in their lifetime. Antibiotic treatment with fluoroquinolones has been associated with the onset of tendinopathy and tendon rupture. The mechanisms behind fluoroquinolone induced tendinopathy remain unclear. To probe activation of potentially causative
Nicole A. Chittim, Amro A. Hussien, Nicolo Dubacher, Gabor Matyas, Jess G. Snedeker   +4 more
wiley   +1 more source

The Burden of Antimicrobial‐Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Erfaneh Jafari, Babak Pourakbari, Mohammad Reza Asadi Karam, Reza Azizian, Mohammad Reza Modaresi, Setareh Mamishi   +5 more
wiley   +1 more source

Protective effects of fluoroquinolones on UV-induced damage of cultured ocular cell lines

, 2017
Takashi Nishida, Yoshiki Kuse, Kiyofumi Mochizuki, Masamitsu Shimazawa, Tetsuya Yamamoto, Hideaki Hara   +5 more
openalex   +2 more sources

Determination of Four Residues of Fluoroquinolones with Similar Structure in Fish by Modified QuEChERS Protocol Coupled toCapillary Electrophoresis(CE) with End-Column Electrochemiluminescence (ECL)

, 2020
Wenjuan Zhang, Fuxiu Yang, Hong Wan, Chunxiu Gu, Kaowen Zhou   +4 more
openalex   +1 more source

Incidence of Fluoroquinolone-Resistant and Extended Spectrum Beta-Lactamase Producing Escherichia coli in African American Males After Transrectal Ultrasound-Guided Prostate Biopsies [PDF]

, 2014
Ali Kazerouni Timsar, Krishna M. Irrinki, Tammey Naab, Chiledum Ahaghotu, Pamela Coleman   +4 more
openalex   +1 more source

Antibiotic Resistance, Biofilm Genes, and smeDEF Efflux Pump in Clinical Stenotrophomonas maltophilia Isolates From Iran

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim, Nisreen Salah Majeed, Asmaa A. Salam, Rania Hameed Hamad, Yeganeh Behrouzi, Erta Rajabi, Razieh Shahbazi   +6 more
wiley   +1 more source

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source