Results 291 to 300 of about 92,879 (318)

The Role of the Fluoroquinolones

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1992
Over the past decade, the quinolone antimicrobial class has enjoyed a renaissance with the emergence of the fluoroquinolone subclass. Norfloxacin, ciprofloxacin, ofloxacin, enoxacin, and lomefloxacin have the advantages of broad antimicrobial activity profiles including gram‐positive and ‐negative aerobes, favorable pharmacokinetic profiles including ...
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Safety of fluoroquinolones in paediatrics

Expert Opinion on Drug Safety, 2002
In the last few years, there has been increasing pressure to use fluoroquinolones in paediatric patients, since these antibiotics offer the advantage of an oral treatment regimen on an out-patient basis. However, even although this class of antibiotics generally remains well-tolerated, the restriction of fluoroquinolone use in children on a ...
Cuzzolin L, FANOS, VASSILIOS
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Fluoroquinolones in the treatment of meningitis

Current Infectious Disease Reports, 2003
The continuous increase of resistant pathogens causing meningitis has limited the efficacy of standard therapeutic regimens. Due to their excellent activity in vitro and their good penetration into the cerebrospinal fluid (CSF), fluoroquinolones appear promising for the treatment of meningitis caused by gram-negative microorganisms, ie, Neisseria ...
Martin G. Täuber, Philippe Cottagnoud
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Seizures Associated with Fluoroquinolones

The Annals of Pharmacotherapy, 2001
OBJECTIVE: To report two cases of seizures following administration of levofloxacin and ciprofloxacin. CASE SUMMARY: A 75-year-old white woman admitted to the hospital was prescribed levofloxacin for ischemic toes. After receiving three doses of oral levofloxacin, the patient experienced a seizure.
Janine M Kushner, Clyde R Snyder, Howard J. Peckman   +2 more
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Fluoroquinolones for the eye

Drug and Therapeutics Bulletin, 1994
Two fluoroquinolone antibiotics, ciprofloxacin (Ciloxan - Alcon) and ofloxacin (Exocin - Allergan), are available in the UK as topical preparations for the eye.* Ciprofloxacin eyedrops are licensed for the treatment of "corneal ulcers and superficial infections of the eye", and ofloxacin eyedrops for "external ocular infections (such as conjunctivitis ...
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Fluoroquinolone Toxicities

Drugs, 1995
The main types of adverse effects associated with quinolones are uncommon and reversible and vary in frequency among different agents. Phototoxicity appears more frequent with lomefloxacin than with some other quinolones. Three mechanisms have been proposed to explain the neurotoxic effects, including rare proconvulsant activity, associated with ...
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Fluoroquinolones

Journal of the American Academy of Orthopaedic Surgeons, 2002
Alan M, Levine, John R, DiBona
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Fluoroquinolones and the risk of tendon injury: a systematic review and meta-analysis

European Journal of Clinical Pharmacology, 2019
C. Alves, D. Mendes, F. Marques
semanticscholar   +1 more source

Adverse Effects of the Fluoroquinolones

Clinical Infectious Diseases, 1988
Data on adverse reactions due to the quinolone antibacterial agents--ciprofloxacin, ofloxacin, pefloxacin, norfloxacin, and enoxacin--observed in a patient sample of approximately 30,000 are reviewed. Overall rates of adverse reactions were 4.0%-8.0%, and adverse reactions necessitated discontinuation of therapy in 1.0%-2.6% of patients.
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Degradation and transformation of fluoroquinolones by microorganisms with special emphasis on ciprofloxacin

Applied Microbiology and Biotechnology, 2019
Marina Rusch, Astrid Spielmeyer, H. Zorn, G. Hamscher   +3 more
semanticscholar   +1 more source