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Infectious Disease Clinics of North America, 2004
This article discusses the newer fluoroquinolones in detail with respect to their pharmacokinetics, pharmacodynamics, safety, and spectrum of in vitro activity. The newer agents are compared and contrasted with the older ones, particularly ciprofloxacin.
Steven P. Gelone, Judith A. O'Donnell
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This article discusses the newer fluoroquinolones in detail with respect to their pharmacokinetics, pharmacodynamics, safety, and spectrum of in vitro activity. The newer agents are compared and contrasted with the older ones, particularly ciprofloxacin.
Steven P. Gelone, Judith A. O'Donnell
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Infectious Disease Clinics of North America, 1995
Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear.
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Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear.
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Dysglycaemias and Fluoroquinolones
Drug Safety, 2008The fluoroquinolones are an extremely popular class of antibacterials, owing to their broad spectrum of activity and the convenience of their intravenous and oral dosage formulations. Overall, the currently available fluoroquinolones have a good safety profile; however, certain fluoroquinolones within the class have been associated with severe and life-
Roshan J. Lewis, John F. Mohr
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Fluoroquinolones in Paediatrics
Paediatric Drugs, 2001The fluoroquinolones are an important group of antibiotics, which are widely used in adult patients because of their high penetration in tissues and bactericidal activity. However, they are not licensed for paediatric use (except the limited indication of Pseudomonas infection in cystic fibrosis) because of their potential to cause joint toxicity ...
Dominique Gendrel, Florence Moulin
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The fluoroquinolones - reappraisal
International Journal of Antimicrobial Agents, 1992The fluoroquinolones (FQ) still appear to draw major interest despite the fact that they have already been used for about a decade. The International Journal of Antimicrobial Agents has published four extensive reviews on norfloxacin, pefloxacin, ciprofloxacin, ofloxacin in its recent issues; two thirds of the pages of the first issue of the journal ...
Claude Carbon, Ethan Rubinstein
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Fluoroquinolones in Paediatrics
Drugs, 1999Fluoroquinolones have a broad spectrum of activity against gram-positive, gram-negative, and mycobacterial organisms as well as anaerobes, Mycoplasma, Chlamydia, Ureaplasma, and Legionella spp. They have excellent oral bioavailability, with good tissue penetration, and long elimination half-lives. The experience with fluoroquinolones in paediatrics has
George H. McCracken, Hasan S. Jafri
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, 2017
Improper disposal of effluents from bulk drug manufacturing units creates a pathway for antibiotics to enter the aquatic environment. This study investigated the presence and distribution of antibiotics belonging to fluoroquinolone group (ciprofloxacin ...
Ritu Gothwal, Shashidhar
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Improper disposal of effluents from bulk drug manufacturing units creates a pathway for antibiotics to enter the aquatic environment. This study investigated the presence and distribution of antibiotics belonging to fluoroquinolone group (ciprofloxacin ...
Ritu Gothwal, Shashidhar
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Fluoroquinolones and Aortic Disease
JAMA Internal Medicine, 2021ND
Gatti M., Raschi E., De Ponti F.
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Environmental Science and Technology, 2014
There is increasing concern that environmental antibiotic pollution promotes transfer of resistance genes to the human microbiota. Here, fluoroquinolone-polluted river sediment, well water, irrigated farmland, and human fecal flora of local villagers ...
C. Rutgersson +9 more
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There is increasing concern that environmental antibiotic pollution promotes transfer of resistance genes to the human microbiota. Here, fluoroquinolone-polluted river sediment, well water, irrigated farmland, and human fecal flora of local villagers ...
C. Rutgersson +9 more
semanticscholar +1 more source
The expanding role of fluoroquinolones [PDF]
Disease-a-Month, 2002 There has been a growing rate of resistance among common urinary tract pathogens, such as Escherichia coli, to traditional antimicrobial therapies including the "gold standard" trimethoprim-sulfamethoxazole (TMP-SMX). Consequently, fluoroquinolone antimicrobial agents have taken on an expanding management role for UTIs.
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