Results 291 to 300 of about 283,224 (387)

Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 540-550, March 2025.
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou, Anne Auperin, Jôel Guigay, Sébastien Salas, Sebastien Benzekry   +4 more
wiley   +1 more source

Fecal microbiota transplantation augments 5-fluorouracil efficacy in pancreatic cancer via gut microbiota modulation. [PDF]

Front Microbiol
Li R, Hu Y, Liu Y, Tan X.
europepmc   +1 more source

Synthesis of 3-(Tetrahydro-2-furanyl)-5-fluorouracil

, 1978
M. YASUMOTO, Jun‐ichi Yamashita, Sadao Hashimoto   +2 more
openalex   +2 more sources

Nanoscale Analysis beyond Imaging by Atomic Force Microscopy: Molecular Perspectives on Oncology and Neurodegeneration

Small Science, EarlyView.
Cancer and neurodegeneration share interconnected nanosized molecular pathways. Novel nanobiomedicine approaches promise targeted biomarkers and therapies. Atomic force microscopy (AFM) is invaluable to characterize nanosized biomolecular processes beyond imaging.
Carlos Marcuello, KeeSiang Lim, Giacomo Nisini, Vadim S. Pokrovsky, João Conde, Francesco Simone Ruggeri   +5 more
wiley   +1 more source

β-Hydroxybutyrate promotes chemoresistance and proliferation in breast cancer cells. [PDF]

Biochem Biophys Rep
Mashinchian M, Vandghanooni S, Karamibonari AR, Eskandani M.   +3 more
europepmc   +1 more source

An Asymptomatic Lesion on the Penis

JEADV Clinical Practice, EarlyView.
Brandon Tan, Karen Cheung, Xin Liu, Alexis Daniel Lara Rivero   +3 more
wiley   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source

Acute Cardiotoxicity Induced by 5-Fluorouracil Successfully Treated With Levosimendan: A Case Report. [PDF]

Cureus
Wu-Chin C, Zúñiga-Orlich C, Salas-Segura J, Lostalo-González A, Mora-Jiménez J, Arguedas-Chacón S, Cruz-Mora K, Zavaleta-Monestel E.   +7 more
europepmc   +1 more source

Self‐Disassembling Macroporous Metal–Organic Framework‐Based Micromotors with Magnetically Controlled Motion for Sequential Drug Release

Small Methods, EarlyView.
MOF‐based magnetic micromotors release two drugs in a controlled and sequential manner at the acidic cancer cell media. Abstract Herein, the synthesis of macroporous zeolitic imidazole framework (ZIF)‐based magnetic micromotors (MMs) for the dual encapsulation of 5‐fluorouracil (5‐FU) and doxorubicin (DOX), with pH‐triggered release is described.
Javier Bujalance Fernández, Víctor de la Asunción‐Nadal, Beatriz Jurado Sánchez, Alberto Escarpa   +3 more
wiley   +1 more source

Olaparib, Pembrolizumab, and Carboplatin as First-Line Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Phase II Trial. [PDF]

JCO Oncol Adv
Adkins D, Ley JC, Liu J, Oppelt P.
europepmc   +1 more source