Results 301 to 310 of about 290,304 (371)

Delivery of lipid nanoparticles containing small interfering RNA targeting transmembrane serine protease 4 in a human gastric cancer model using nude mice. [PDF]

Sci Rep
Tazawa H, Ishida Y, Suzuki T, Shimizu Y, Tashiro H.   +4 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

A comparison by mismatch repair status of real‐world characteristics and outcomes in patients with stage II/III rectal cancer in the Netherlands

International Journal of Cancer, Volume 158, Issue 4, Page 963-976, 15 February 2026.
What's new? Mismatch repair deficiency (dMMR) in rectal cancer is rare, and knowledge about tumor biological behavior, response to treatment, and clinical outcomes in this subset of patients is limited. This nationwide cohort study including 182 patients with dMMR rectal cancer found that they were younger and had more poorly differentiated tumors ...
Renee A. Lunenberg, Ingrid A. Franken, Frederieke H. van der Baan, Femke P. C. Sijtsma, Geraldine R. Vink, Manon N. G. J. A. Braat, Leon M. G. Moons, Miangela M. Lacle, Marloes A. G. Elferink, Susan Boklage, Martijn P. W. Intven, Jamie Garside, Miriam Koopman, Rob van Wuijtswinkel, Jeanine M. L. Roodhart   +14 more
wiley   +1 more source

Modified hepatic arterial infusion chemotherapy protocol for reducing perioperative pain and anesthetic consumption in patients with hepatocellular carcinoma. [PDF]

Quant Imaging Med Surg
Li H, Li Y, Kang W, Xi J, Sun W, Liu Y, Yang Z.   +6 more
europepmc   +1 more source

Progesterone receptor (PR) intra‐tumor heterogeneity in premenopausal breast cancer: A secondary analysis of a randomized trial

International Journal of Cancer, Volume 158, Issue 4, Page 1106-1115, 15 February 2026.
What's new? Progesterone receptor (PR) expression in breast cancer is influenced by menopausal status and PR positivity is more common in premenopausal women. The influence of PR intra‐tumor heterogeneity on distant recurrence risk in premenopausal women, however, remains unknown. In this investigation, variations in PR expression within breast tumors,
Oscar Danielsson, Huma Dar, Gizeh Perez‐Tenorio, Anna Nordenskjöld, Christina Yau, Christopher C. Benz, Laura J. Esserman, Bo Nordenskjöld, Olle Stål, Tommy Fornander, Johan Hartman, Nicholas P. Tobin, Annelie Johansson, Linda S. Lindström   +13 more
wiley   +1 more source

Assessment of the Role of Neutrophil-Lymphocyte Ratio as a Prognostic Biomarker in Breast Cancer Patients: A Cross-sectional Study. [PDF]

Cancer Diagn Progn
Takada K, Kashiwagi S, Nishikawa M, Watanabe C, Tauchi Y, Ogisawa K, Shibutani M, Kinoshita H, Morisaki T.   +8 more
europepmc   +1 more source

Uptake of DPYD and UGT1A1 testing in Italy and adherence to pharmacogenetic guidelines: A 5‐year perspective from an EQA provider

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 445-456, February 2026.
Aims Pharmacogenetic implementation requires awareness of the state‐of‐the‐art practice of laboratories providing pharmacogenetic testing. This study investigated how pharmacogenetic guidelines and recommendations have been implemented over time by Italian laboratories participating in the external quality assessment (EQA) Pharmaco‐scheme established ...
Rossana Roncato, Samantha Perfler, Diletta Pasin, Elena Peruzzi, Michael Woodcock, Henry Thomas, Rebecca Goodall, Simon J. Patton, Erika Cecchin   +8 more
wiley   +1 more source

Case Report: Bowen's disease treated with PD-1 inhibitor and chemotherapy. [PDF]

Front Oncol
Xie X, Chen Q, Zhang J, Peng X.
europepmc   +1 more source

Induction chemotherapy with nedaplatin, docetaxel and 5-fluorouracil followed by concurrent nedaplatin and radiotherapy in locoregionally advanced nasopharyngeal carcinoma: A single arm, open label, phase II clinical trial. [PDF]

Transl Oncol
Chen FZ, Deng Y, Yin WJ, Wang MY, Yang F, Yang ZH, Zhou LP, Chen SD, Chen JL, Jiang XZ, Zhou AX, Ou YM, Liu JQ, Chen DP, Qi B.   +14 more
europepmc   +1 more source