Results 351 to 360 of about 283,224 (387)

Topical Fluorouracil in Vitiligo

Archives of Dermatology, 1985
To the Editor.— I was interested to read of the effect of 5-fluorouracil cream in the treatment of vitiligo as reported from Japan by Tsuji and Hamada. 1 They found that while fluorouracil alone had no effect, its use following epidermal abrasion resulted in repigmentation in the majority of patients.
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Leucovorin and fluorouracil vs levamisole and fluorouracil as adjuvant chemotherapy in rectal cancer

Oncology Reports, 2004
The aim of this study was to evaluate the effectiveness of 6-month therapy with leucovorin (LV) + 5-fluorouracil (5-FU) vs 12 months of therapy with levamisole (LVZ) + 5-FU, as adjuvant chemotherapy in patients with completely resected Dukes' stage B2 or C rectal cancer.
George C. Zografos, K. Gennatas, Panayiotis Gouveris, G Karatzas, K Fotiadis, Gregory Kouraklis, M Safioleas, D Voros, M Paraskevaidis, M Balafouta, J. Vasiliou, Christos Kosmas, Skopelitis H, Efstathios Papalambros, G. Papastratis, M Zacharakis, E Felekouras, A. Dimitrakopoulos, N. Tsavaris   +18 more
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Phase III study of tri-modality combination therapy with induction docetaxel plus cisplatin and 5-fluorouracil versus definitive chemoradiotherapy for locally advanced unresectable squamous-cell carcinoma of the thoracic esophagus (JCOG1510: TRIANgLE).

Japanese Journal of Clinical Oncology, 2019
A randomized phase III trial commenced in Japan in February 2018. Definitive chemoradiotherapy (CRT) with cisplatin plus 5-fluorouracil is the current standard treatment for locally advanced unresectable esophageal carcinoma. The purpose of this study is
Mitsumi Terada, H. Hara, H. Daiko, J. Mizusawa, T. Kadota, K. Hori, H. Ogawa, T. Ogata, K. Sakanaka, Takeshi Sakamoto, Ken Kato, Y. Kitagawa   +11 more
semanticscholar   +1 more source

5-Fluorouracil and Derivatives in Cancer Chemotherapy: Determination of 5-Fluorouracil in Blood

Journal of Pharmaceutical Sciences, 1972
The current work describes a dialysis technique which separates 5-fluorouracil from interfering blood components and allows for subsequent GC determinations. The parameters affecting the dialysis and GC are presented. The results indicate that 5-fluorouracil is present in the free and bound states in blood, and the method is capable of distinguishing ...
J.L. Sutter, John J. Windheuser, E. Auen
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5-Fluorouracil for glaucoma surgery

Cochrane Database of Systematic Reviews, 2014
Trabeculectomy is performed as a treatment for many types of glaucoma in an attempt to lower the intraocular pressure. The surgery involves creating a channel through the sclera, through which intraocular fluid can leave the eye. If scar tissue blocks the exit of the surgically created channel, intraocular pressure rises and the operation fails ...
Catey Bunce, Mark R Wilkins, Elspeth Green, Richard Wormald   +3 more
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Treatment of Hypertrophic Scars Using Laser-Assisted Corticosteroid Versus Laser-Assisted 5-Fluorouracil Delivery

Dermatologic Surgery, 2019
BACKGROUND As the mortality of individuals suffering severe cutaneous injuries decreases, there is an increased need to improve the methods by which physicians treat the resultant scars.
J. Waibel, Adam J. Wulkan, Ashley Rudnick, A. Daoud   +3 more
semanticscholar   +1 more source

Levofolinate and fluorouracil combination therapy.

Folia Pharmacologica Japonica, 2001
Levofolinate and fluorouracil regimen (l-leucovorin and 5 fluorouracil regimen) is a biochemical modulation of 5 fluorouracil (5FU) by leucovorin (LV). In the USA and Europe d,l-LV and 5FU regimen is frequently administered for colorectal cancer treatment and recognized as the standard regimen.
Shigemi Takeuchi, Minoru Murakami
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Treatment of Keratoacanthomas With Intralesional Fluorouracil

Archives of Dermatology, 1978
Fourteen patients with 26 keratoacanthomas (KA) were treated weekly with intralesional injections of fluorouracil. Twenty-five lesions cleared in an average of three weeks (range, two to eight weeks) after an average of 2.8 injections. One KA failed to respond after five weekly injections and was excised.
Richard B. Odom, Detlef K. Goette
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5-Fluorouracil rechallenge after 5-fluorouracil-induced hyperammonemic encephalopathy

Anti-Cancer Drugs, 2019
For several decades, 5-Fluorouracil (5-FU) has been the backbone of many chemotherapy regimens for various tumor types. Its most common side effects are gastrointestinal disorders, mucositis, myelosuppression, hand-foot syndrome, and rarely cardiac toxicity. More rarely, 5-FU infusion can induce hyperammonemic encephalopathy.
Michel Ducreux, Clément Pontoizeau, Clément Pontoizeau, Alice Boilève, Alice Boilève, Antoine Hollebecque, Camille Wicker, Camille Wicker, Benjamin Verret, Chris Ottolenghi, Chris Ottolenghi, Pascale de Lonlay, Pascale de Lonlay, Mathieu Jozwiak, Florence Leroy, David Malka   +15 more
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5-Fluorouracil and dihydropyrimidine dehydrogenase

International Journal of Clinical Oncology, 2003
Dihydropyrimidine dehydrogenase (DPD) is a rate-limiting enzyme of (fluorinated) pyrimidine degradation that plays a significant role in the pharmacokinetics of 5-fluorouracil (5-FU). In addition, a catabolite of 5-FU induces a certain toxicity, and the sensitivity of 5-FU is determined by DPD activity in tumors. DPD is thus important clinically. Drugs
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