Results 141 to 150 of about 52,362 (245)

Photobiocatalytic Linear Deracemization of β‐Hydroxynitriles

open access: yesChemSusChem, Volume 19, Issue 19, 14 October 2026.
Photosensitizers were screened for the oxidation of β‐hydroxynitriles under blue light irradiation, finding tetra‐n‐butyl decatungstate as the most suitable catalyst for accessing ketonitriles. Subsequently, bioreductions were carried out, leading to the identification of stereocomplementary alcohol dehydrogenases for the development of a linear ...
Sara Filgueira   +2 more
wiley   +1 more source

Compound Ciwujia Granules Attenuate Stress‐Induced Anxiety‐ and Depression‐Like Behaviors via Inhibition of TNF‐α‐Associated Neuroinflammation in the dmPFC

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
By restoring glutamatergic neuronal activity, suppressing TNF‐related inflammatory signaling pathway, and reducing microglial overactivation in the dmPFC, CWJ ameliorated stress‐induced behavioral abnormalities. ABSTRACT Aims Compound Ciwujia Granules (CWJ) have shown antidepressant‐like effects, but the neural and molecular mechanisms underlying these
Fei Tian   +9 more
wiley   +1 more source

Anticonvulsant effect of intranigral fluoxetine

open access: yes, 1992
Bilateral focal injections of the serotonin uptake inhibitor, fluoxetine (1.75-7.0 nmol) into substantia nigra (SN) protected against convulsive seizures evoked by the focal injection of bicuculline methiodide into area tempestas, an epileptogenic site ...
Tortorella, A   +4 more
core   +1 more source

Design and Evaluation of Fluoxetine Orodispersible Tablets. [PDF]

open access: yes, 2012
This study is to design and development of fluoxetine oral disintegrant tablet by using different superdisintegrants like crospovidone, croscarmellose sodium and sodium starch glycolate.
Gangadhar, B B
core  

Sociability Under Anthropogenic Change: From Individual Behaviour to Population‐Level Consequences

open access: yesEcology and Evolution, Volume 16, Issue 10, October 2026.
Our review synthesises empirical and theoretical research on how anthropogenic environmental change reshapes animal social behaviour from individuals to populations. We use sociability as an individual‐level lens, distinguishing context‐dependent expression from repeatable interindividual differences and linking both to social relationships, network ...
Paulina Kowalczyk, Barbara Pietrzak
wiley   +1 more source

Relation between Fluoxetine and Menstrual Cycle Disorders

open access: yesJournal of Family and Reproductive Health, 2012
Objective: To investigate the effect of fluoxetine as an SSRI on menstrual disorders. Materials and methods: In this cross-sectional study 200 women referring to the Islamic Azad University affiliated hospitals during March 2011- March 2010 were divided ...
Zhila Amirkhani   +7 more
doaj  

Myelin Impairment and Regeneration in the Central Nervous System: Molecular Mechanisms, Diseases, and Prospective Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Proper myelin formation is crucial for normal neural circuit function, while myelin deficiency can lead to neural circuit dysfunction and cognitive decline, notably in Alzheimer's disease and other central nervous system demyelinating disorders. This review summarizes central myelin's structure and function, demyelination biomarkers and pathological ...
Lihong Huang   +5 more
wiley   +1 more source

Both Genetic Manipulation and Acupuncture Alleviate Depressive‐Like Behavior Mediated by Astrocytic P2X7 Receptors

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The efficacy of the chronic unpredictable mild stress (CUMS) model in mice was assessed using the tail suspension test (TST; A) and the forced swim test (FST; B). In both major depressive disorder (MDD) mouse models, CUMS significantly increased immobility time, indicating the development of depressive‐like behavior.
Wen‐Jing Ren   +8 more
wiley   +1 more source

Updated Estimates of Agreement Between Dispensed Medications and Forensic Toxicology in Sweden

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose To present updated estimates from a nationwide Swedish study comparing dispensed medications with forensic toxicological findings (2006–2013), following re‐evaluation of the toxicology dataset to address periods with non‐uniform analytical detection and inconsistent testing.
Heidi Taipale   +3 more
wiley   +1 more source

Concurrent Antidepressant Use and Metastasis Risk Among Women Receiving Tamoxifen for Breast Cancer: A Real‐World Cohort Study

open access: yesPsycho-Oncology, Volume 35, Issue 10, October 2026.
ABSTRACT Objective Concurrent use of antidepressants, particularly cytochrome P450 2D6 (CYP2D6) inhibitors, may reduce tamoxifen bioactivation and effectiveness. However, the clinical significance of this potential interaction remains inconclusive. This study examined whether concurrent antidepressant use is associated with increased metastasis risk ...
Shaimaa Elshafie   +4 more
wiley   +1 more source

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