Results 141 to 150 of about 80,403 (271)
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric +3 more
wiley +1 more source
Celebration Schedule 2015 (Friday)
Full presentation schedule for Celebration, Friday, May 1 ...
Provost\u27s Office,
core
Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade +5 more
wiley +1 more source
Effects of Agomelatine on Sleep Across Populations: A Systematic Review and Meta‐Analysis
ABSTRACT Agomelatine, a melatoninergic antidepressant, is often prescribed to improve sleep disturbance, though meta‐analytic evidence is currently lacking. This systematic review and meta‐analysis assessed its efficacy and tolerability in sleep outcomes compared to placebo.
Anastasios Stefanou +7 more
wiley +1 more source
Abstract Objectives To understand the impact of and subsequent reactions to exposure to extreme violence in young adults in South Africa exposed during school years. In particular, to get an in‐depth understanding of its immediate consequences and factors that ameliorate or exacerbate it.
Marinos Bomikazi Lupindo +2 more
wiley +1 more source
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen +7 more
wiley +1 more source
Case Report: Fluoxetine-induced leucocytoclastic vasculitis. [PDF]
Qin Y, Yao J, Jiang X, Chen W.
europepmc +1 more source
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan +11 more
wiley +1 more source
Fluoxetine Repurposing Mitigates Alzheimer's Disease Pathology via the GSK3β-CREB-ADAM10 Axis. [PDF]
Lee SH +6 more
europepmc +1 more source
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman +6 more
wiley +1 more source

