Results 141 to 150 of about 116,874 (255)

Preclinical Imaging for the Translation of Innovative Nutritional Strategies: Current Applications and Future Perspectives. [PDF]

J Imaging
Yamaoka I.
europepmc   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

Long-term control of <i>Legionella pneumophila</i> and <i>Pseudomonas aeruginosa</i> in dental unit waterlines following optimization of a hypochlorous acid-based water safety program. [PDF]

Front Oral Health
Wolf A, Abdullah TEA, Moritz A, Georgopoulos A.   +3 more
europepmc   +1 more source

Climate Change is Rewriting the Hydroclimatic Operating Envelope of Mines

Advanced Science, EarlyView.
Climate change is shown to shift the hydroclimatic operating envelope of mines: 16.2% of represented mine locations have already changed Köppen subtype, rising to 42.5% by late century under SSP5‐8.5. Divergent water trajectories are filtered through geology, infrastructure and lifecycle stage, indicating that adaptation requires monitored, scenario ...
Haoxuan Yu, Izni Zahidi, Chow Ming Fai, Jilong Pan   +3 more
wiley   +1 more source

Prevention and management of hormonal crisis in neuroendocrine tumors undergoing PRRT (peptide receptor radionuclide therapy): a systematic review. [PDF]

ESMO Gastrointest Oncol
Arrivi G, Pagnanelli M, Puliani G, Zerbi A, Partelli S, Panzuto F.   +5 more
europepmc   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

Reusing Haemodialysis Reverse Osmosis Reject Water: A Case Report From a Sydney Metropolitan Hospital, Australia. [PDF]

Can J Kidney Health Dis
Hsu WY, Huang B, Lees S, Veros H, Smyth B, Mangos G, Gallagher A.   +6 more
europepmc   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source

A dual-table technique facilitates vascular control and successful repair of a suprarenal inferior vena cava injury. [PDF]

J Vasc Surg Cases Innov Tech
Kilada C, Robitsek J, McKenzie K, Jimenez JC, Guerges M.   +4 more
europepmc   +1 more source