Results 171 to 180 of about 116,874 (255)

CaMKIIδ Phosphorylates AUP1 to Promote Pancreatic Tissue Repair and Acinar‐to‐Ductal Metaplasia Formation via Mediating PERK‐Dependent Unfolded Protein Responses

Advanced Science, EarlyView.
CaMKIIδ–AUP1 signaling maintains PERK‐dependent ER homeostasis during ADM‐mediated pancreatic repair. ABSTRACT Pancreatic repair after acute pancreatitis (AP) is essential for restoring tissue integrity, but the intrinsic mechanisms coordinating acinar plasticity and regeneration remain poorly understood.
Yonghao Chen, Ziying Han, Zihan Yang, Jie Wu, Kaixin Peng, Xiuli Zhang, Bintao Qiu, Jianqiang Wu, Xiaomin Hu, Dong Wu, Li Wen   +10 more
wiley   +1 more source

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen, Xiaoxiao Chen, Baozhu Yang, Hui Xu, Xueting Sun, Hongkai Qi, Huilin Hu, Ronghua Wu, Fengkai Qiu, Bing Wu, Yu Luo, Gaofeng Shu, Jiansong Ji   +12 more
wiley   +1 more source

Effect of Short-Term Increases in Feed Allowances on Growth and Sexual Development in Previously Feed-Restricted Gilts. [PDF]

Vet Sci
Niblett T, Williams K, Cross M, Clapp A, Estienne M.   +4 more
europepmc   +1 more source

Enhancing Surface Icephobic Performance via Spontaneous Fracture Characteristics of Ice Crystals Regulated by Structural Scale Under Shear Flow Conditions

Advanced Science, EarlyView.
Aerodynamic shear induces spontaneous ice fracture and detachment on hydrophobic surfaces, governed by the interplay between initial ice‐crystal size, growth orientation, and interfacial adhesion. Unexpectedly, microstructural anchoring on superhydrophobic surfaces suppresses ice shedding.
Jiawei Jiang, Yizhou Shen, Yangjiangshan Xu, Junxian Xiang, Weilan Liu, Senyun Liu, Lingfeng Zhao, Jie Tao, Zhong Chen   +8 more
wiley   +1 more source

Flow Behaviour of Liquid and Gaseous Dielectrics and Debris Transport in the Inter-Electrode Gap of Micro-EDM Milling: A CFD Study. [PDF]

Micromachines (Basel)
Bigdeli M, Modica FG, Marrocco V, Fassi I.   +3 more
europepmc   +1 more source

Controllable Superconductivity in Suspended NbSe2

Advanced Electronic Materials, EarlyView.
Suspended NbSe2${\rm NbSe}_2$ provides two complementary routes for controlling superconducting transport. Gate‐driven deformation strains the suspended crystal and tunes its critical temperature and current. Weak thermal anchoring enhances thermal feedback, contributing to multistep hysteresis and negative differential resistance.
Ruihuan Fang, Cuiju Yu, Youqiang Huang, Tosson Elalaily, Yuvraj Chaudhry, Yaoqiang Zhou, Andres Castellanos‐Gomez, Sanshui Xiao, Jiwon Park, Hyunyong Choi, Fida Ali, Hanlin Fang, Jose L. Lado, Pertti Hakonen, Zhipei Sun   +14 more
wiley   +1 more source

Blunted Niacin Skin Flushing Response in Schizophrenia: A Meta-analysis. [PDF]

Schizophr Bull
Wang J, Wang Q, Wang D, Gao Y, Li S, Wang T, Liu H, Wang H, Hu X, Wan C.   +9 more
europepmc   +1 more source

A Compact Hollow Fiber Electrode Assembly Architecture for Continuous Electrochemical Marine Carbon Dioxide Removal

Advanced Energy Materials, EarlyView.
A coaxial, membrane‐integrated hollow fiber electrode assembly (HFEA) is developed for continuous marine carbon mineralization. By utilizing a sub‐millimeter inter‐electrode gap, the HFEA minimizes Ohmic losses, achieving 50% energy reduction and over 85% DIC removal.
Inhwan Park, Young Hun Lee, Jung Hun Lee, Seung‐Jeong Oh, T. Alan Hatton, Dong‐Yeun Koh   +5 more
wiley   +1 more source