Results 201 to 210 of about 254,231 (333)

Enabling Real‐Time Shape‐Sensing in Soft Robots via a Miniaturized, Single‐Signal, Color‐Tuned Soft Optical Sensor

open access: yesAdvanced Robotics Research, EarlyView.
A miniaturized soft optical sensor that uses thin film color tuning enables real‐time 3D shape‐sensing from a single red–green–blue (RGB) signal. When integrated into a soft robot, it enables closed‐loop control and autonomous navigation in a phantom lung environment without the need for onboard electronics, achieving sub‐millimeter accuracy through ...
Frank Juliá Wise   +6 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan   +10 more
wiley   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

open access: yesAdvanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo   +6 more
wiley   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

open access: yesAdvanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu   +14 more
wiley   +1 more source

Man with rash on left hand

open access: yesJournal of the American College of Emergency Physicians Open, 2020
Neeraj Chimanji   +2 more
doaj   +1 more source

A successful staged approach for treatment of concomitant mitral insufficiency and mycotic aneurysmCentral Message

open access: yesJTCVS Techniques, 2020
Eric Zimmermann, MD   +3 more
doaj   +1 more source

Vancomycin Flushing Syndrome Due to Oral Vancomycin in Chronic Kidney Disease Patients: A Case Report

open access: diamond, 2022
Swarada Yadav   +4 more
openalex   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

open access: yesAdvanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo   +40 more
wiley   +1 more source

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