Results 221 to 230 of about 254,231 (333)
Proceedings of the National Academy of Sciences of the United States of America, 2014 Yongshuo H. Fu +9 more
semanticscholar +1 more source
DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss
Advanced Science, EarlyView.Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim +11 more
wiley +1 more source
Well Injection Depth Extraction (WIDE) Soil Flushing. Innovative Technology Summary Report
, 2001 DOE Ohio Field Office, Ashtabula Environmental Management Project, Ashtabula, Ohio (US)
openalex +2 more sources
Targeted water releases to flush fine sediment out of a bypassed reach of the Durance River downstream of four dams [PDF]
, 2018 Rémi Loire +5 more
openalex +1 more source
Advanced Science, EarlyView.This study presents a novel 4D bioprinting platform for engineering biomimetic musculoskeletal grafts. By tuning the mechanical properties of support baths, we enhance tissue fusion, collagen alignment, and cell differentiation. Using this strategy, we successfully fabricate scaled‐up, anisotropic tissues such as meniscus, articular cartilage, and ...
Francesca D. Spagnuolo +2 more
wiley +1 more source
Improvement of sludge electrodewatering by anode flushing
, 2016 M. Citeau, M. Loginov, E. Vorobiev
semanticscholar +1 more source
Advanced Science, EarlyView.Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang +16 more
wiley +1 more source
Botulinum Toxin for the Treatment of Refractory Erythema and Flushing of Rosacea
Dermatology, 2015 K. Park +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi +18 more
wiley +1 more source