Results 281 to 290 of about 263,228 (334)

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

open access: yesAdvanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang   +13 more
wiley   +1 more source

The impact of a bundle for the prevention of central venous catheter-associated bloodstream infections in an pediatric surgery intensive care unit. [PDF]

open access: yesGMS Hyg Infect Control
Devrim İ   +12 more
europepmc   +1 more source

Dynamics of water balance elements and periodic flushing regime of leached chernozem

open access: diamond
Nikolai Vasilievich Smolin   +6 more
openalex   +2 more sources

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

open access: yesAdvanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai   +15 more
wiley   +1 more source

Is Bariatric Surgery at Risk Due to Semaglutide? [PDF]

open access: yesJ Metab Bariatr Surg
Tian J   +8 more
europepmc   +1 more source

Defect‐Free Sb‐Doping in Bi2O2Se Achieves Two‐Order‐of‐Magnitude Reduction in Saturation Intensity While Preserving High Carrier Mobility

open access: yesAdvanced Science, EarlyView.
This study demonstrates defect‐free states Sb3⁺ doping in Bi2O2Se, enhancing carrier mobility while reducing saturation intensity by about two orders of magnitude. First‐principles calculations and experiments reveal optimized electronic structure and improved nonlinear response.
Qingling Tang   +4 more
wiley   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

open access: yesAdvanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das   +13 more
wiley   +1 more source

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