Results 41 to 50 of about 250,488 (285)

A Case of Necrotizing Fasciitis Mimicking a Burn in an Elderly Patient

Case Reports in Surgery, 2023
Necrotizing fasciitis travels along the fascial plane and surrounding soft tissue, leading to ischemia and necrosis. Fournier’s gangrene is a type of necrotizing fasciitis invading the deep and superficial planes of the perineal/genital region.
Madiha Khan, Shubham Bhatia, Kelly L. Cervellione, Martine A. Louis   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A Rare Case of Histiocytic Sarcoma Secondary to Gastrointestinal Stromal Tumor in the Stomach: Transdifferentiation or Synchronicity?

Case Reports in Hematology, 2021
Histiocytic sarcoma is a rare malignant histiocytic neoplasm composed of cells with morphologic and immunophenotypic features of mature tissue histiocytes. It occurs anywhere in the body and behaves aggressively. However, its etiology is unknown.
Jiankun Tong, Jean Luo, Pierre F. Saldinger, William H. Rodgers   +3 more
doaj   +1 more source

Pinpointing drivers of widespread colonization of Legionella pneumophila in a green building: Roles of water softener system, expansion tank, and reduced occupancy

Frontiers in Water, 2023
IntroductionLegionella pneumophila is an opportunistic pathogen that is a key contributor to drinking water-associated disease outbreaks in the United States.
Sayalee Joshi, Sayalee Joshi, Rain Richard, Carlos Levya, Joanna Ciol Harrison, Joanna Ciol Harrison, Daniella Saetta, Naushita Sharma, Naushita Sharma, Lucas Crane, Lucas Crane, Noelle Mushro, Noelle Mushro, Lucien Dieter, Lucien Dieter, Grace V. Morgan, Ashley Heida, Bennett Welco, Bennett Welco, Treavor H. Boyer, Treavor H. Boyer, Paul Westerhoff, Paul Westerhoff, Kerry A. Hamilton, Kerry A. Hamilton   +24 more
doaj   +1 more source

Collection and freezing of equine epididymal spermatozoa [PDF]

, 2014
The epididymis and vas deferens store an important number of fertile spermatozoa called the extragonadal sperm reserves. These stored spermatozoa can be collected in an ultimate attempt to preserve viable spermatozoa of a critically ill or dying stallion.
Govaere, Jan, Hoogewijs, Maarten, Leemans, Bart, Roels, Kim, Van Soom, Ann, Ververs, Cyrillus   +5 more
core   +1 more source

Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study [PDF]

, 2015
Intracoronary optical frequency domain imaging (OFDI), requires the displacement of blood for clear visualization of the artery wall. Radiographic contrast agents are highly effective at displacing blood however, may increase the risk of contrast-induced
Asanani, Nayan, Bouma, Brett E, Bouma, Brett E., Conditt, Gerard B., Gallagher, Kevin A., Granada, Juan F., Kaluza, Greg L., Kashiwagi, Manabu, Milewski, Krzysztof, Nadkarni, Seemantini K., Suter, Melissa J., Tanaka, Atsushi, Tearney, Guillermo J., Tellez, Armando   +13 more
core   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Use of Daptomycin for the Treatment of Methicillin-Resistant Coagulase-Negative Staphylococcal Ventriculitis

Case Reports in Medicine, 2012
Coagulase-negative staphylococci (CoNS) are the main pathogens causing hospital-acquired external-ventricular-drain- (EVD-) and lumbar-drain- (LD-) associated meningitis and ventriculitis.
Mohamed Erritouni, Nessrine Ktaich, James J. Rahal, Deborah Figueroa, Jaime Nieto, Carl Urban, Noriel Mariano, Frank Eisinger, Jonathan Abayev, David Nicolau, David Rubin, Murisiku Raifu, Sorana Segal-Maurer   +12 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Aspects of classification and diagnostic search for transient and persistent facial erythema

Лечащий Врач, 2021
Rosacea is one of the most common conditions on the face. Rosacea affecting the central parts of the face and is characterized by erythema, flushing, telangiectasia; papules and pustules.
T. А. Sysoeva, I. Е. Frolova, E. К. Murakhovskaya, A. S. Bisharova, I. B. Mertsalova   +4 more
doaj   +1 more source