Results 61 to 70 of about 11,222 (199)

Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]

, 2005
This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony, Holz, Olaf, Janicki, Stanislawa, Jörres, Rudolf A., Kanniess, Frank, Magnussen, Helgo, Richter, Kai, Simpson, Kathy J., Tal-Singer, Ruth, Vessey, Rupert S. J.   +9 more
core   +1 more source

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 109-119, January 2026.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang, Kevin J. O’Leary, Edith A. Nutescu, Matthew Jack, Thomas Chen, Gregory W. Ruhnke, James C. Lee, David George, Larry K. House, Randall Knoebel, Luke V. Rasmussen, Seth Hartman, Anish Choksi, Kiang‐Teck J. Yeo, Minoli A. Perera, Mark J. Ratain, David O. Meltzer, Peter H. O’Donnell   +17 more
wiley   +1 more source

IMPACT OF THE TYPE OF A BASIC THERAPY ON THE QUALITY OF LIFE IN CHILDREN WITH CONTROLLED MODERATELY SEVERE BRONCHIAL ASTHMA

Педиатрическая фармакология, 2010
The article provides results of a study for the impact of low doses fluticasone propionate and sodium nedocromil on the quality of life in children with bronchial asthma. It evidences Statistically valid improvements in the quality of life are identified
S.V. Bychkovskaya, N.A. Il'enkova, S.Yu. Tereschenko   +2 more
doaj   +2 more sources

Cost‐Effectiveness Analysis of Treatments for Children With Uncontrolled Asthma Symptoms Despite Inhaled Corticosteroids

Pediatric Pulmonology, Volume 60, Issue 12, December 2025.
ABSTRACT Introduction There is uncertainty about the cost‐effectiveness of treatment options for children and adolescents with uncontrolled asthma despite inhaled corticosteroid (ICS) treatment. Methods A Markov state‐transition model was developed to simulate costs from the perspective of the National Health Service in the UK and health outcomes ...
Giovanna Culeddu, Sofia Cividini, Ian Sinha, Sarah Donegan, Katie Rose, Olivia Fulton, Stephen Turner, Catrin Tudur Smith, Dyfrig A. Hughes, EINSTEIN collaborative group   +9 more
wiley   +1 more source

Fluticasone propionate-salmeterol versus inhaled corticosteroids plus montelukast: outcomes study in pediatric patients with asthma

Journal of Asthma and Allergy, 2012
Richard H Stanford,1 Manan Shah,2 Anna O D'Souza21GlaxoSmithKline, Research Triangle Park, Durham, NC, 2Xcenda, Palm Harbor, FL, USABackground: The purpose of this study (GSK ADA111194) was to compare asthma-related health care utilization and ...
Stanford RH, Shah M, D'Souza AO
doaj  

Low-dose Fluticasone Propionate in Combination With Salmeterol in Patients With Chronic Obstructive Pulmonary Disease

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2018
Inhaled corticosteroids are widely used in the treatment of chronic obstructive pulmonary disease (COPD). However, their use has been questioned for appropriate dose and a possible increased risk of pneumonia. Here, we reviewed patients with COPD who had
Hideki Yasui, Naoki Inui, Tomoyuki Fujisawa, Masato Karayama, Noriyuki Enomoto, Yutaro Nakamura, Shigeki Kuroishi, Hisano Ohba, Koshi Yokomura, Jun Sato, Masaki Sato, Naoki Koshimizu, Mikio Toyoshima, Takashi Yamada, Masafumi Masuda, Toshihiro Shirai, Takafumi Suda   +16 more
doaj   +1 more source

Is There a Topical Nasal Steroid Spray That Works the Best for Nasal Congestion?

The Laryngoscope, EarlyView.
Benjamin Aunins, Samuel Oyer, Vusala Snyder, Stephen Park   +3 more
wiley   +1 more source

Comparison of Allergic Rhinitis Treatments on Patient Satisfaction: A MASK‐air and EAACI Methodological Committee Report

Allergy, Volume 80, Issue 12, Page 3319-3330, December 2025.
This study compares different medications for allergic rhinitis on patients' satisfaction and co‐medication use frequency. mHealth data suggest that intranasal corticosteroids (INCS) and fixed combinations of intranasal antihistamines (INAH) and corticosteroids are associated with higher treatment satisfaction than oral antihistamines (OAH).
Bernardo Sousa‐Pinto, Rafael José Vieira, Antonio Bognanni, Matteo Martini, Michal Ordak, Giovanni Paoletti, Sara Gil‐Mata, Rita Amaral, Anna Bedbrook, Patrizia Bonadonna, Luisa Brussino, G. Walter Canonica, João Coutinho‐Almeida, Álvaro A. Cruz, Wienczyslawa Czarlewski, Mark Dykewicz, Mattia Giovannini, Bilun Gemicioglu, Juan Carlos Ivancevich, Ludger Klimek, Violeta Kvedariene, Desiree E. Larenas‐Linnemann, Manuel Marques‐Cruz, André Moreira, Marek Niedoszytko, Ana Margarida Pereira, Nikolaos G. Papadopoulos, Nhan Pham‐Thi, Frederico S. Regateiro, Sanna K. Toppila‐Salmi, Boleslaw Samolinski, Joaquin Sastre, Luís Taborda‐Barata, Tuuli Thomander, Ilgım Vardaloğlu Koyuncu, Arunas Valiulis, Leticia de las Vecillas, Maria Teresa Ventura, Jolanta Walusiak‐Skorupa, Yi‐Kui Xiang, Oliver Pfaar, João A. Fonseca, Torsten Zuberbier, Holger J. Schünemann, Danilo di Bona, Jean Bousquet   +45 more
wiley   +1 more source

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events. [PDF]

, 2018
BACKGROUND: Epidemiological evidence has suggested a link between use of beta₂-agonists and increased asthma mortality. Much debate has surrounded possible causal links for this association, and whether regular (daily) long-acting beta₂-agonists (LABAs ...
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core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Nuclear hormone receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S242-S258, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, John A. Cidlowski, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laurel Coons, Peter J. Fuller, Kenneth S. Korach, Donald P. McDonell, Robert Oakley, Sarah Radi, Rachid Safi, Frances Sladek, Morag J. Young   +20 more
wiley   +1 more source