Results 111 to 120 of about 177,434 (388)

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

open access: yesAdvanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan   +16 more
wiley   +1 more source

Minimum mass sizing of a large low-aspect ratio airframe for flutter-free performance [PDF]

open access: yes
A procedure for sizing an airframe for flutter-free performance is demonstrated on a large, flexible supersonic transport aircraft. The procedure is based on using a two level reduced basis or modal technique for reducing the computational cost of ...
Greene, W. H.   +1 more
core   +1 more source

RAB5A Promotes Active Fluid Wetting by Reprogramming Breast Cancer Spheroid Mechanics

open access: yesAdvanced Science, EarlyView.
RAB5A‐mediated unjamming enhances active wetting through distinct biomechanical processes: a) upregulation of specific integrin subunits, enhanced focal adhesions kinetics and activity; b) supracellular organization relying on nanoscale integrin clustering, and the formation of a stiff and collective actin cable; and c) softening of the spheroid core ...
Grégoire Lemahieu   +19 more
wiley   +1 more source

Development of aeroelastic analysis methods for turborotors and propfans, including mistuning [PDF]

open access: yes
The NASA Lewis aeroelastic research program is focused on unstalled and stalled flutter, forced response, and whirl flutter of turborotors and propfans.
Kaza, Krishna Rao V.
core   +1 more source

Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK‐3β/β‐Catenin Signaling

open access: yesAdvanced Science, EarlyView.
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan   +5 more
wiley   +1 more source

Multifunction tests of a frequency domain based flutter suppression system [PDF]

open access: yes
The process is described of analysis, design, digital implementation, and subsonic testing of an active control flutter suppression system for a full span, free-to-roll wind tunnel model of an advanced fighter concept.
Adams, William M., Jr.   +1 more
core   +1 more source

Controllable Preparation of Millimeter‐Scale In‐Plane Charged Domain Wall in a Lead‐Free Ferroelectric Film

open access: yesAdvanced Science, EarlyView.
This study presents an effective method for fabricating millimeter‐scale continuous in‐plane head‐to‐head charged domain walls by controlling the growth of the Na0.5Bi0.5TiO3 film. The formation of antiphase boundaries plays a crucial role in stabilizing the charged domain walls. Atomic‐scale insights reveal that the dynamic coupling among polarization,
Fang Liu   +7 more
wiley   +1 more source

Evaluation of four subcritical response methods for on-line prediction flutter onset in wind-tunnel tests [PDF]

open access: yes
The methods were evaluated for use in tests where the flutter model is excited solely by airstream turbulence. The methods were: randomdec, power-spectral-density, peak-hold, and cross-spectrum.
Doggett, R. V., Jr.   +3 more
core   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao   +20 more
wiley   +1 more source

Wind Tunnel Measurements for Flutter of a Long-Afterbody Bridge Deck

open access: yesItalian National Conference on Sensors, 2017
Bridges are an important component of transportation. Flutter is a self-excited, large amplitude vibration, which may lead to collapse of bridges. It must be understood and avoided.
Zengshun Chen   +3 more
semanticscholar   +1 more source

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