Results 81 to 90 of about 22,174,492 (295)

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye   +9 more
wiley   +1 more source

Flutter analysis and simulated flutter test of wings

open access: yes, 2020
Çırpıntı, hava aracında ölümcül sonuçlara yol açabilecek dinamik bir kararsızlıktır. Çırpıntıyı önlemek, hava aracının yapısal tasarımını da etkileyen önemli bir tasarım girdisidir. Hava aracının ağırlığı ve performansı da bu girdiden etkilenir. Kanat tasarım faktörlerinin çırpıntı oluşumundaki rolünün anlaşılması tasarımcılara çırpıntı açısından ...
openaire   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Universal Battery Capacity Degradation Forecasting Driven by Foundation Models Across Diverse Chemistries and Conditions

open access: yesAdvanced Science, EarlyView.
A unified time‐series forecasting framework learns transferable battery capacity‐degradation patterns from 20 heterogeneous datasets spanning chemistries, formats, temperatures, and cycling conditions. A single model delivers competitive predictions on both known and previously unseen datasets, while physics‐guided representation learning improves ...
Joey Chan   +8 more
wiley   +1 more source

Aerodynamic Analysis of Blade Stall Flutter Prediction for Transonic Compressor Using Energy Method

open access: yesAerospace
In this study, stall flutter onset prediction in a transonic compressor is carried out using the (uncoupled) energy method with Fourier transform. As the study is conducted computationally using computational fluid dynamics (CFD)-based simulations, the ...
Ali Arshad, Akshay Murali
doaj   +1 more source

A ROM based flutter prediction process and its validation with a new reference model [PDF]

open access: yes, 2011
Industrial flutter prediction for large transport aircraft requires numerical capabilities to predict unsteady aerodynamic forces induced by harmonic oscillations for the complete flight envelope including transonic and separated flow conditions, with ...
Tichy, Lorenz   +2 more
core  

Model of Mobile Application Using Flutter Framework

open access: yes, 2021
Метою кваліфікаційної роботи є розробка моделі мобільного застосунку з використанням фреймворка Flutter. У ході виконання кваліфікаційної роботи була розроблена модель додатоку для купівлі в магазинах з використанням фреймоврку Flutter та мови ...
Чепелєв, Є. О.
core  

Analysis of Friction-Saturated Flutter Vibrations With a Fully Coupled Frequency Domain Method

open access: yes, 2020
Flutter stability is a dominant design constraint of modern turbines. Thus, flutter-tolerant designs are currently explored, where the resulting vibrations remain within acceptable bounds.
Gross, Johann   +3 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Subsonic Flutter of Cantilever Rectangular PC Plate Structure

open access: yesInternational Journal of Aerospace Engineering, 2016
Flutter characteristics of cantilever rectangular flexible plate structure under incompressible flow regime are investigated by comparing the results of commercial flutter analysis program ZAERO© with wind tunnel tests conducted in Ankara Wind Tunnel ...
Kemal Yaman
doaj   +1 more source

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