Results 181 to 190 of about 36,253 (296)
A Comprehensive Echocardiographic Assessment of Patients With Chronic Myeloid Leukemia on Dasatinib
In a retrospective cohort of 199 adult patients with CML on Dasatinib in a single quaternary center, approximately 25% patients had routine baseline and follow‐up echocardiogram. Dasatinib was associated with significant changes in structural and diastolic parameters.
Chen Chen +4 more
wiley +1 more source
ABSTRACT Introduction Novel targeted agents have transformed the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), including continuous BTK inhibitor (BTKi) therapy and time‐limited regimens such as venetoclax‐obinutuzumab (Ven‐O) and ibrutinib‐venetoclax (I + V).
Rebecca Tidswell +7 more
wiley +1 more source
Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives
ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gianluca Gaidano, Romano Danesi
wiley +1 more source
In this retrospective single‐center study of 1018 routine Holter ECG recordings from 167 patients with Duchenne muscular dystrophy, nonsustained ventricular tachycardia and frequent premature ventricular complexes were common. Reduced left ventricular function was the strongest associated factor, supporting regular Holter monitoring for patients at ...
Ryo Sugiyama +6 more
wiley +1 more source
A Comprehensive Assessment of Renal Function During and After Pulsed Field Ablation
ABSTRACT Background Acute kidney injury is an uncommon complication of pulsed field ablation (PFA). There is, however, limited empirical data on the dynamics of renal biomarkers apart from creatinine. Furthermore, no study to date has assessed creatinine at more than 24 h after the procedure. Methods Patients undergoing PFA for atrial fibrillation (AF)
Václav Melenovský +10 more
wiley +1 more source
ABSTRACT Introduction Pulsed field ablation (PFA) is an established therapy for atrial fibrillation (AF), yet optimal mapping strategies during pentaspline PFA remain uncertain. We compared procedural characteristics and material costs of an integrated 3D electroanatomic mapping (EAM) platform with conventional mapping systems. Methods and Results In a
Auroa Badin +9 more
wiley +1 more source
Comparison of HEMOlysis Markers Among Three Pulsed Field Ablation Systems: HEMO‐PFA Study
ABSTRACT Background Pulsed field ablation (PFA) has emerged as a novel non‐thermal modality for atrial fibrillation (AF) ablation. While hemolysis is a known complication of PFA, comparative data among different systems remain limited. Methods We prospectively enrolled 150 consecutive AF patients undergoing ablation with one of three PFA systems ...
Kazuhisa Matsumoto +11 more
wiley +1 more source
British Journal of Haematology, Volume 208, Issue 6, Page 2320-2325, June 2026.
Barbara Gianesin +29 more
wiley +1 more source

