Results 211 to 220 of about 2,518,547 (340)
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
COBRAxy: constraint-based metabolic modeling in Galaxy. [PDF]
Lapi F +5 more
europepmc +1 more source
Validity domain and saturation behavior of a surface-flux proxy in the radial acceleration relation
Pedde, Reinhold
openalex +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Comparison of clinical therapeutic effects between high-flux dialysis and low-flux dialysis. [PDF]
Li Y +22 more
europepmc +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Exploring CHO cell stability during prolonged passaging via eXplainable AI driven flux balance analysis. [PDF]
Choi DH +6 more
europepmc +1 more source

