Results 91 to 100 of about 1,136,141 (298)
A Topological Characterization of Medium-Dependent Essential Metabolic Reactions
Metabolites, 2012 Metabolism has frequently been analyzed from a network perspective. A major question is how network properties correlate with biological features like growth rates, flux patterns and enzyme essentiality.
Nikolaus Sonnenschein +2 more
doaj +1 more source
Microorganisms, 2021 Serine/threonine kinase PknB and its corresponding phosphatase Stp are important regulators of many cell functions in the pathogen S. aureus. Genome-scale gene expression data of S.
Chunguang Liang +9 more
doaj +1 more source
An analytic approximation of the feasible space of metabolic networks
, 2017 Assuming a steady-state condition within a cell, metabolic fluxes satisfy an under-determined linear system of stoichiometric equations. Characterizing the space of fluxes that satisfy such equations along with given bounds (and possibly additional ...
Braunstein, Alfredo +2 more
core +1 more source
Elucidating dynamic metabolic physiology through network integration of quantitative time-course metabolomics. [PDF]
, 2017 Efst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn To access publisher's full text version of this article.
Bordbar, Aarash +5 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Flux balance analysis of mycolic acid pathway: targets for anti-tubercular drugs.
PLoS Computational Biology, 2005 Mycobacterium tuberculosis is the focus of several investigations for design of newer drugs, as tuberculosis remains a major epidemic despite the availability of several drugs and a vaccine.
Karthik Raman +2 more
doaj +2 more sources
Flux Balance Analysis Indicates that Methane Is the Lowest Cost Feedstock for Microbial Cell Factories. [PDF]
Metab Eng Commun, 2017 Comer AD, Long MR, Reed JL, Pfleger BF.
europepmc +2 more sources
A thermodynamically consistent kinetic framework for binary nucleation [PDF]
, 2007 The traditional theory for binary homogeneous nucleation follows the classical derivation of the nucleation rate in the supposition of a hypothetical constrained-equilibrium distribution in the calculation of the cluster evaporation rate.
Flagan, Richard C.
core +1 more source
Flux balance analysis of biological systems: applications and challenges [PDF]
Briefings in Bioinformatics, 2009 Systems level modelling and simulations of biological processes are proving to be invaluable in obtaining a quantitative and dynamic perspective of various aspects of cellular function. In particular, constraint-based analyses of metabolic networks have gained considerable popularity for simulating cellular metabolism, of which flux balance analysis ...
Raman, Karthik, Chandra, Nagasuma
openaire +2 more sources