Finding branched pathways in metabolic network via atom group tracking.
PLoS Computational Biology, 2021 Finding non-standard or new metabolic pathways has important applications in metabolic engineering, synthetic biology and the analysis and reconstruction of metabolic networks.
Yiran Huang +3 more
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A toolbox model of evolution of metabolic pathways on networks of arbitrary topology. [PDF]
PLoS Computational Biology, 2011 In prokaryotic genomes the number of transcriptional regulators is known to be proportional to the square of the total number of protein-coding genes.
Tin Yau Pang, Sergei Maslov
doaj +3 more sources
Evidencing strain-dependency of metabolic pathways within 1,494 lactic bacteria genomes with the in silico screening Prolipipe pipeline [PDF]
PeerJGenomes from bacteria of interest to the food industry exhibit significant functional variability, yet evaluating this characteristic remains challenging.
Noé Robert +4 more
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Serum and urine metabolomic biomarkers for predicting prognosis in patients with immunoglobulin A nephropathy [PDF]
Kidney Research and Clinical Practice, 2023 Background Immunoglobulin A nephropathy (IgAN) is the most prevalent form of glomerulonephritis worldwide. Prediction of disease progression in IgAN can help to provide individualized treatment based on accurate risk stratification.
You Hyun Jeon +7 more
doaj +1 more source
Metabolomic approaches applied to the study of cervical cancer: a systematic review
Brazilian Journal of Oncology, 2022 Background: Cervical cancer (CC) is the fourth leading cause of cancer among women in the world. Metabolomics can provide a deeper understanding of the underlying metabolic alterations associated with its pathophysiology ...
Natalia Damasceno Almeida +3 more
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Integrated RNA-sequencing and network analysis approach to identify the Hub genes and vital pathways associated with gastric cancer [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: Gastric cancer is one of the most prevalent types of cancer in developing countries and ranks fourth in terms of death causes. Helicobacter pylori infection is a significant contributor to the emergence of gastric cancer. Lack of early diagnosis
Karthick Vasudevan +12 more
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Clustering analysis of tumor metabolic networks
BMC Bioinformatics, 2020 Background Biological networks are representative of the diverse molecular interactions that occur within cells. Some of the commonly studied biological networks are modeled through protein-protein interactions, gene regulatory, and metabolic pathways ...
Ichcha Manipur +3 more
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MetNet: A two-level approach to reconstructing and comparing metabolic networks.
PLoS ONE, 2021 Metabolic pathway comparison and interaction between different species can detect important information for drug engineering and medical science. In the literature, proposals for reconstructing and comparing metabolic networks present two main problems ...
Nicoletta Cocco +3 more
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The link between ferroptosis and airway inflammatory diseases: A novel target for treatment
Frontiers in Molecular Biosciences, 2022 Ferroptosis is an iron-dependent mode of cell death characterized by intracellular lipid peroxide accumulation and a redox reaction imbalance. Compared with other modes of cell death, ferroptosis has specific biological and morphological features.
Zhiwei Lin +5 more
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Metabolic pathways variability and sequence/networks comparisons
BMC Bioinformatics, 2006 Background In this work a simple method for the computation of relative similarities between homologous metabolic network modules is presented. The method is similar to classical sequence alignment and allows for the generation of phenotypic trees ...
Palumbo Maria +3 more
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