Results 1 to 10 of about 374,876 (335)

Linkage of Organic Anion Transporter-1 to Metabolic Pathways through Integrated “Omics”-driven Network and Functional Analysis [PDF]

, 2011
Sun-Young Ahn, Neema Jamshidi, Monica L. Mo, Wei Wu, Satish A. Eraly, Ankur V. Dnyanmote, Kevin T. Bush, Tom F. Gallegos, Douglas H. Sweet, Bernhard Ø. Palsson, Sanjay K. Nigám   +10 more
openalex   +1 more source

Immunometabolism: crosstalk with tumor metabolism and implications for cancer immunotherapy

Molecular Cancer
Immunometabolism has established a groundbreaking paradigm for cancer immunotherapy by decoding the intricate interaction networks between metabolic pathways and immune responses. This review comprehensively explores the metabolic reprogramming of immune
Huiru Zhang, Jialiang Fan, Deyang Kong, Yu Sun, Qi Zhang, Renshen Xiang, Shuaibing Lu, Wenjing Yang, Lin Feng, Haizeng Zhang   +9 more
doaj   +1 more source

Bile acid–microbiota interactions in cardiometabolic diseases: mechanisms and emerging therapeutic approaches

Frontiers in Microbiology
The gut microbiota and bile acids co-regulate host metabolism through bidirectional interactions. This interaction critically influences the pathogenesis and progression of cardio-metabolic diseases (CMDs), which include diabetes, obesity, non-alcoholic ...
Feiyu Chen, Feiyu Chen, Lihong Gong, Lihong Gong   +3 more
doaj   +1 more source

Find_tfSBP: find thermodynamics-feasible and smallest balanced pathways with high yield from large-scale metabolic networks [PDF]

, 2017
Zixiang Xu, Jibin Sun, Qiaqing Wu, Dunming Zhu   +3 more
openalex   +1 more source

Additional file 1 of Global connectivity in genome-scale metabolic networks revealed by comprehensive FBA-based pathway analysis

, 2021
Yajie Gao, Qianqian Yuan, Zhitao Mao, Hao Liu, Hongwu Ma   +4 more
openalex   +1 more source

Thermodynamic analysis of computed pathways integrated into the metabolic networks of E. coli and Synechocystis reveals contrasting expansion potential

, 2017
Johannes Asplund‐Samuelsson, Markus Janasch, Elton P. Hudson   +2 more
openalex   +1 more source

How enzyme economy shapes metabolic fluxes

, 2014
Metabolic fluxes are governed by physical and economic principles. Stationarity constrains them to a subspace in flux space and thermodynamics makes them lead from higher to lower chemical potentials.
Liebermeister, Wolfram
core  

Toolbox model of evolution of metabolic pathways on networks of arbitrary topology [PDF]

, 2010
Tin Yau Pang, Sergei Maslov
openalex   +1 more source

Understanding flux switching in metabolic networks through an analysis of synthetic lethals

npj Systems Biology and Applications
Biological systems are robust and redundant. The redundancy can manifest as alternative metabolic pathways. Synthetic double lethals are pairs of reactions that, when deleted simultaneously, abrogate cell growth. However, removing one reaction allows the
Sowmya Manojna Narasimha, Tanisha Malpani, Omkar S. Mohite, J. Saketha Nath, Karthik Raman   +4 more
doaj   +1 more source

Cotton metabolism regulatory network: Unraveling key genes and pathways in fiber development and growth regulation

Plant Communications
Cotton (Gossypium hirsutum L.) is one of the world's most important commercial crops. However, the dynamics of metabolite abundance and potential regulatory networks throughout its life cycle remain poorly understood. In this study, we developed a cotton metabolism regulatory network (CMRN) that spans various developmental stages and encompasses 2138 ...
Liu, Zhao, Fan, Liqiang, Shu, Sheng, Qanmber, Ghulam, Chen, Eryong, Huang, Jinquan, Li, Fuguang, Yang, Zuoren   +7 more
openaire   +2 more sources