Representing and analysing molecular and cellular function in the computer [PDF]
Determining the biological function of a myriad of genes, and understanding how they interact to yield a living cell, is the major challenge of the post genome-sequencing era.
Wodak, SJ +6 more
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Role of Ferroptosis in Lung Diseases
Wenting Xu,1,2,* Huimin Deng,2,* Song Hu,2,3,* Yiguo Zhang,2,3 Li Zheng,1,2 Meiyun Liu,2 Yuanli Chen,2 Juan Wei,2 Hao Yang,2 Xin Lv1– 3 1Department of Anesthesiology, Fuyang Hospital of Anhui Medical University, Fuyang, Anhui, 236000, People&rsquo ...
Xu W +9 more
doaj
Peritoneal dialysis influences microRNA expression and pro-inflammatory response: results from a cross-sectional study [PDF]
Introduction: The investigation of circulating microRNAs (miRNAs) and inflammatory response associated with the different stages of chronic kidney disease (CKD) may reveal biomarkers of disease pathogenesis. Our goal was to identifying differences in the
Nara Aline Costa +14 more
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Comparative Pathway Analyzer - a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms [PDF]
Oehm S, Gilbert D, Tauch A, Stoye J, Goesmann A. Comparative Pathway Analyzer - a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms. NUCLEIC ACIDS RESEARCH.
Gilbert, David +9 more
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Alignment of Linear Biochemical Pathways Using Protein Structural Classification [PDF]
Metabolic, signaling and regulatory pathways form the basis of biological processes and are important for the analysis of cellular behavior and evolution.
Timm Oberwahrenbrock +7 more
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The Metabolic Phenotype of Prostate Cancer
Prostate cancer is the most common non-cutaneous cancer in men in the United States. Cancer metabolism has emerged as a contemporary topic of great interest for improved mechanistic understanding of tumorigenesis.
Eric Eidelman +5 more
doaj +1 more source
MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
Kierzek, A.M. +42 more
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Fungal secondary metabolites are widely used as therapeutics and are vital components of drug discovery programs. A major challenge hindering discovery of novel secondary metabolites is that the underlying pathways involved in their biosynthesis are ...
Min Jin Kwon +8 more
doaj +1 more source
Systems approaches to modelling pathways and networks. [PDF]
Peer ...
Christian, Nils +5 more
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Systematic assignment of thermodynamic constraints in metabolic network models [PDF]
Background: The availability of genome sequences for many organisms enabled the reconstruction of several genome-scale metabolic network models. Currently, significant efforts are put into the automated reconstruction of such models.
Kümmel, Anne, +12 more
core +2 more sources

