Results 41 to 50 of about 218,906 (301)

Phylophenetic properties of metabolic pathway topologies as revealed by global analysis

BMC Bioinformatics, 2006
Background As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components.
Sun Shiwei, Zhang Zefeng, Zhu Xiaopeng, Zhang Zhihua, Skogerbø Geir, Li Shaojuan, Zhang Yong, Lu Hongchao, Shi Baochen, Chen Runsheng   +9 more
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Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition [PDF]

, 2011
The quantification of experimentally-induced alterations in biological pathways remains a major challenge in systems biology. One example of this is the quantitative characterization of alterations in defined, established metabolic pathways from complex ...
Dawson, Neil, Xiaolin Xiao, Brian J Morris, Xiao, X., Higham, Desmond, MacIntyre, L., Pratt, J.A., Morris, Brian J., MacIntyre, Lynsey, Higham, Desmond J, Higham, D.J., Desmond J Higham, Watson, David, Neil Dawson, Watson, David G., Judith A Pratt, Xiao, Xiaolin, Morris, B.J., Pratt, Judith, David G Watson, Pratt, Judith A., Dawson, N., Lynsey MacIntyre, Watson, D.G., Morris, Brian   +24 more
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A statistical mechanics description of environmental variability in metabolic networks

, 2014
Many of the chemical reactions that take place within a living cell are irreversible. Due to evolutionary pressures, the number of allowable reactions within these systems are highly constrained and thus the resulting metabolic networks display ...
Crofts, J.J., Crofts, JJ, Estrada, E, Estrada, Ernesto   +3 more
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Quantitative proteomic characterization of human sperm cryopreservation: using data-independent acquisition mass spectrometry

BMC Urology, 2019
Background Human sperm cryopreservation is a simple and effective approach for male fertility preservation. Methods To identify potential proteomic changes in this process, data-independent acquisition (DIA), a technology with high quantitative accuracy ...
Longlong Fu, Qi An, Kaishu Zhang, Ying Liu, Yue Tong, Jianfeng Xu, Fang Zhou, Xiaowei Wang, Ying Guo, Wenhong Lu, Xiaowei Liang, Yiqun Gu   +11 more
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Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival [PDF]

, 2011
Hypoxia is one of the features of poorly vascularised areas of solid tumours but cancer cells can survive in these areas despite the low oxygen tension.
Tennant, D.A., Zheng, L, Appanna, VD, Watson David G., Kalna, G., Hedley Barbara A., Papkovsky, Dmitri B, Gottlieb Eyal, Papkovsky, D.B., Christian Frezza, Dmitri B. Papkovsky, Frezza, Christian, Hedley, Barbara A, Zheng Liang, Liang Zheng, Hedley, BA, Watson, DG, Kalna, Gabriela, Dmitri B Papkovsky, Tennant, Daniel A., Gabriela Kalna, Frezza, C, Watson, David, Eyal Gottlieb, Tennant Daniel A., Gottlieb, Eyal, Gottlieb, E., David G. Watson, Frezza Christian, Kalna Gabriela, Hedley, B., Daniel A Tennant, Frezza, C., Kalna, G, Barbara A. Hedley, Zheng, L., Barbara A Hedley, Tennant, Daniel; id_orcid, Gottlieb, E, David G Watson, Papkovsky, DB, Papkovsky Dmitri B., Zheng, Liang, Watson, D.G., Daniel A. Tennant   +44 more
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Cancer metabolism: a modeling perspective

Frontiers in Physiology, 2015
Tumor cells alter their metabolism to maintain unregulated cellular proliferation and survival, but this transformation leaves them reliant on constant supply of nutrients and energy.
Pouyan eGhaffari Nouran, Adil eMardinoglu, Adil eMardinoglu, Jens eNielsen, Jens eNielsen, Jens eNielsen   +5 more
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Discriminating response groups in metabolic and regulatory pathway networks [PDF]

Bioinformatics, 2012
Abstract Motivation: Analysis of omics experiments generates lists of entities (genes, metabolites, etc.) selected based on specific behavior, such as changes in response to stress or other signals. Functional interpretation of these lists often uses category enrichment tests using functional annotations like Gene Ontology terms and ...
John L. Van Hemert, Julie A. Dickerson
openaire   +2 more sources

On functional module detection in metabolic networks

, 2013
Functional modules of metabolic networks are essential for understanding the metabolism of an organism as a whole. With the vast amount of experimental data and the construction of complex and large-scale, often genome-wide, models, the computer-aided ...
Koch, Ina, Ackermann, Jörg, Ina Koch, Jörg Ackermann   +3 more
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Library of Apicomplexan Metabolic Pathways: a manually curated database for metabolic pathways of apicomplexan parasites. [PDF]

, 2012
The Library of Apicomplexan Metabolic Pathways (LAMP, http://www.llamp.net) is a web database that provides near complete mapping from genes to the central metabolic functions for some of the prominent intracellular parasites of the phylum Apicomplexa ...
Wastling
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Deciphering rice metabolic flux reprograming under salinity stress via in silico metabolic modeling

Computational and Structural Biotechnology Journal, 2020
Rice is one of the most economically important commodities globally. However, rice plants are salt susceptible species in which high salinity can significantly constrain its productivity. Several physiological parameters in adaptation to salt stress have
Kwanjeera Wanichthanarak, Chuthamas Boonchai, Thammaporn Kojonna, Supachitra Chadchawan, Wichian Sangwongchai, Maysaya Thitisaksakul   +5 more
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