Results 31 to 40 of about 374,876 (335)

MetNet: A two-level approach to reconstructing and comparing metabolic networks.

PLoS ONE, 2021
Metabolic pathway comparison and interaction between different species can detect important information for drug engineering and medical science. In the literature, proposals for reconstructing and comparing metabolic networks present two main problems ...
Nicoletta Cocco, Mercè Llabrés, Mariana Reyes-Prieto, Marta Simeoni   +3 more
doaj   +1 more source

A Bioinformatics-Assisted Review on Iron Metabolism and Immune System to Identify Potential Biomarkers of Exercise Stress-Induced Immunosuppression

Biomedicines, 2022
The immune function is closely related to iron (Fe) homeostasis and allostasis. The aim of this bioinformatics-assisted review was twofold; (i) to update the current knowledge of Fe metabolism and its relationship to the immune system, and (ii) to ...
Diego A. Bonilla, Yurany Moreno, Jorge L. Petro, Diego A. Forero, Salvador Vargas-Molina, Adrián Odriozola-Martínez, Carlos A. Orozco, Jeffrey R. Stout, Eric S. Rawson, Richard B. Kreider   +9 more
doaj   +1 more source

MetExploreViz: web component for interactive metabolic network visualization [PDF]

, 2017
Summary: MetExploreViz is an open source web component that can be easily embedded in any web site. It provides features dedicated to the visualization of metabolic networks and pathways and thus offers a flexible solution to analyse omics data in a ...
Chazalviel, Maxime, Cottret, Ludovic, Frainay, Clément, Gloaguen, Yoann, Jourdan, Fabien, Merlet, Benjamin, Poupin, Nathalie, Vinson, Florence   +7 more
core   +4 more sources

Extreme Pathway Lengths and Reaction Participation in Genome-Scale Metabolic Networks [PDF]

Genome Research, 2002
Extreme pathways are a unique and minimal set of vectors that completely characterize the steady-state capabilities of genome-scale metabolic networks. A framework is provided to mathematically characterize extreme pathway length and to study how individual reactions participate in the extreme pathway structure of a network.
Jason A, Papin, Nathan D, Price, Bernhard Ø, Palsson   +2 more
openaire   +2 more sources

Benchmarking procedures for high-throughput context specific reconstruction algorithms

Frontiers in Physiology, 2016
Recent progress in high-throughput data acquisition has shifted the focus from data generation to processing and understanding of how to integrate collected information.
Maria ePires Pacheco, Thomas ePfau, Thomas eSauter   +2 more
doaj   +1 more source

The link between ferroptosis and airway inflammatory diseases: A novel target for treatment

Frontiers in Molecular Biosciences, 2022
Ferroptosis is an iron-dependent mode of cell death characterized by intracellular lipid peroxide accumulation and a redox reaction imbalance. Compared with other modes of cell death, ferroptosis has specific biological and morphological features.
Zhiwei Lin, Xiaojing Yang, Lili Guan, Lijie Qin, Jiabin Ding, Luqian Zhou   +5 more
doaj   +1 more source

Reconstruction of metabolic pathways by combining probabilistic graphical model-based and knowledge-based methods [PDF]

, 2014
Automatic reconstruction of metabolic pathways for an organism from genomics and transcriptomics data has been a challenging and important problem in bioinformatics.
Jianlin Cheng, Jilong Li, Qi Qi
core   +2 more sources

Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel [PDF]

Journal of Occupational & Environmental Medicine, 2016
The aim of this study is to use high-resolution metabolomics (HRM) to identify metabolic pathways and networks associated with tobacco use in military personnel.Four hundred deidentified samples obtained from the Department of Defense Serum Repository were classified as tobacco users or nonusers according to cotinine content.
Dean P, Jones, Douglas I, Walker, Karan, Uppal, Patricia, Rohrbeck, Col Timothy M, Mallon, Young-Mi, Go   +5 more
openaire   +2 more sources

Role of Ferroptosis in Lung Diseases

Journal of Inflammation Research, 2021
Wenting Xu,1,2,* Huimin Deng,2,* Song Hu,2,3,* Yiguo Zhang,2,3 Li Zheng,1,2 Meiyun Liu,2 Yuanli Chen,2 Juan Wei,2 Hao Yang,2 Xin Lv1– 3 1Department of Anesthesiology, Fuyang Hospital of Anhui Medical University, Fuyang, Anhui, 236000, People&rsquo ...
Xu W, Deng H, Hu S, Zhang Y, Zheng L, Liu M, Chen Y, Wei J, Yang H, Lv X   +9 more
doaj  

MetaboCraft: building a Minecraft plugin for metabolomics [PDF]

, 2018
Motivation: The rapid advances in metabolomics pose a significant challenge in presentation and interpretation of results. Development of new, engaging visual aids is crucial to advancing our understanding of new findings. Results: We have developed
Burgess, Karl, Daly, Rónán, Megalios, Anargyros   +2 more
core   +1 more source