Results 31 to 40 of about 218,906 (301)
Metabolic Reprogramming in Triple-Negative Breast Cancer
Frontiers in Oncology, 2020 Metabolic reprogramming is an emerging hallmark of cancer cells, in which cancer cells exhibit distinct metabolic phenotypes to fuel their proliferation and progression.
Xiangyu Sun +9 more
doaj +1 more source
Functional prediction of environmental variables using metabolic networks
Scientific Reports, 2021 In this manuscript, we propose a novel approach to assess relationships between environment and metabolic networks. We used a comprehensive dataset of more than 5000 prokaryotic species from which we derived the metabolic networks.
Adèle Weber Zendrera +2 more
doaj +1 more source
The Metabolic Phenotype of Prostate Cancer
Frontiers in Oncology, 2017 Prostate cancer is the most common non-cutaneous cancer in men in the United States. Cancer metabolism has emerged as a contemporary topic of great interest for improved mechanistic understanding of tumorigenesis.
Eric Eidelman +5 more
doaj +1 more source
Pathway-Consensus Approach to Metabolic Network Reconstruction for Pseudomonas putida KT2440 by Systematic Comparison of Published Models. [PDF]
PLoS ONE, 2017 Over 100 genome-scale metabolic networks (GSMNs) have been published in recent years and widely used for phenotype prediction and pathway design.
Qianqian Yuan +9 more
doaj +1 more source
Metabolic network visualization eliminating node redundance and preserving metabolic pathways [PDF]
BMC Systems Biology, 2007 AbstractBackgroundThe tools that are available to draw and to manipulate the representations of metabolism are usually restricted to metabolic pathways. This limitation becomes problematic when studying processes that span several pathways. The various attempts that have been made to draw genome-scale metabolic networks are confronted with two ...
Romain Bourqui +6 more
openaire +3 more sources
Systematic assignment of thermodynamic constraints in metabolic network models [PDF]
, 2006 Background: The availability of genome sequences for many organisms enabled the reconstruction of several genome-scale metabolic network models. Currently, significant efforts are put into the automated reconstruction of such models.
Kümmel, Anne, +12 more
core +1 more source
Frontiers in Endocrinology, 2023 Glioma is a type of brain tumor closely related to abnormal cell metabolism. Firstly, multiple combinatorial sequencing studies have revealed this relationship.
Xianlei Yan +8 more
doaj +1 more source
VitisCyc: A metabolic pathway knowledgebase for grapevine (Vitis vinifera)
Frontiers in Plant Science, 2014 We have developed VitisCyc, a grapevine-specific metabolic pathway database that allows researchers to i) search and browse the database for its various components such as metabolic pathways, reactions, compounds, genes and proteins, ii) compare ...
Sushma eNaithani +6 more
doaj +1 more source
Visual Network Analysis of Dynamic Metabolic Pathways [PDF]
, 2010 We extend our previous work on the exploration of static metabolic networks to evolving, and therefore dynamic, pathways. We apply our visualization software to data from a simulation of early metabolism. Thereby, we show that our technique allows us to test and argue for or against different scenarios for the evolution of metabolic pathways.
Markus Rohrschneider +4 more
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Metabolic PathFinding: inferring relevant pathways in biochemical networks [PDF]
Nucleic Acids Research, 2005 Our knowledge of metabolism can be represented as a network comprising several thousands of nodes (compounds and reactions). Several groups applied graph theory to analyse the topological properties of this network and to infer metabolic pathways by path finding.
Didier Croes +3 more
openaire +4 more sources