Results 101 to 110 of about 5,574,042 (346)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A DETERMINATION OF THE FLUX DENSITY IN CORE OF DISTRIBUTION TRANSFORMERS, WHAT BUILT WITH THE COMMON USING OF GRAIN AND NON GRAIN ORIENTED MAGNETIC STEELS

Electrical engineering & Electromechanics, 2015
Purpose. The development of calculation method to determinate the flux densities in different parts of the magnetic cores of distribution transformers, what built from different types magnetic steel (mixed core). Methodology.
I.V. Pentegov, S.V. Rymar, M.I. Levin, A.V. Lavreniuk   +3 more
doaj  

Heat Flux at the Surface of Metal Foil Heater under Evaporating Sessile Droplets

International Journal of Aerospace Engineering, 2015
Evaporating water drops on a horizontal heated substrate were investigated experimentally. The heater was made of a constantan foil with the thickness of 25 μm and size of 42 × 35 mm2.
Igor Marchuk, Andrey Karchevsky, Anton Surtaev, Oleg Kabov   +3 more
doaj   +1 more source

Flux domes in superconducting films without edges

, 2006
Domelike magnetic-flux-density distributions previously have been observed experimentally and analyzed theoretically in superconducting films with edges, such as in strips and thin plates. Such flux domes have been explained as arising from a combination
D. C. Baird, F. Haenssler, I. L. Maksimov, I. L. Maksimov, John R. Clem, Yasunori Mawatari   +5 more
core   +1 more source

The intergalactic medium thermal history at redshift z=1.7--3.2 from the Lyman alpha forest: a comparison of measurements using wavelets and the flux distribution [PDF]

, 2012
We investigate the thermal history of the intergalactic medium (IGM) in the redshift interval z=1.7--3.2 by studying the small-scale fluctuations in the Lyman alpha forest transmitted flux.
A. Garzilli, Becker, Becker, Becker, Bird, Bolton, Bolton, Bolton, Calura, Chang, Dall'Aglio, Eisenstein, Fan, Faucher-Giguère, Fendt, Feroz, Feroz, Freedman, Furlanetto, Haardt, Hui, Hui, J. S. Bolton, Kim, Larson, Lee, Lewis, Lidz, Lidz, M. Viel, Madau, McDonald, McDonald, McQuinn, McQuinn, Meiksin, Mukherjee, Pawlik, Peeples, Peeples, Puchwein, Raskutti, Ricotti, S. Leach, Schaye, Shull, Skilling, Slosar, Springel, Syphers, T.-S. Kim, Tepper-García, Theuns, Theuns, Theuns, Theuns, Tittley, Tornatore, Tytler, Viel, Viel, Worseck, Zaldarriaga, Zaldarriaga   +63 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Impact of Flux-Modulated Rotor Design on Special Flux Density Harmonics in PS-DSPM for Cogging Torque Minimization

Journal of Applied Science and Engineering
High cogging torque caused by a fluctuating magnetic flux distribution in the partitioned stator doubly salient permanent magnet machines (PS-DSPM), due to their double air gap design, limits their application despite excellent torque density ...
Wilaiphorn Nokklang, Pattasad Saengwong, Apirat Siritaratiwat, Warat Sriwannarat   +3 more
doaj   +1 more source