Results 111 to 120 of about 1,062,938 (302)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Internal drainage and nitrate leaching in a corn-black oat-corn succession with two split nitrogen applications

Scientia Agricola, 2006
Excessive nitrate leaching represents a potential groundwater contamination. This study was carried out in an experiment area located in the city of Piracicaba/SP- Brazil, on a sandy-clayey loam soil.
Flávia Carvalho Silva Fernandes, Paulo Leonel Libardi, Laércio Alves de Carvalho   +2 more
doaj  

Statistical Analysis of Pulsar Flux Density Distribution

The Astrophysical Journal
This study presents a comprehensive analysis of the spectral properties of 886 pulsars across a wide frequency range from 20 MHz–343.5 GHz, including a total of 86 millisecond pulsars (MSPs).
H. W. Xu, R. S. Zhao, Erbil Gugercinoglu, H. Liu, D. Li, P. Wang, C. H. Niu, C. Miao, X. Zhu, R. W. Tian, W. L. Li, S. D. Wang, Z. F. Tu, Q. J. Zhi, S. J. Dang, L. H. Shang, S. Xiao   +16 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Mesoscopic Charge Density Wave in a Magnetic Flux

, 1998
The stability of a Charge Density Wave (CDW) in a one-dimensional ring pierced by a Aharonov-Bohm flux is studied in a mean-field picture. It is found that the stability depends on the parity of the number $N$ of electrons.
Montambaux, Gilles
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

An electrochemical method for measuring magnetic flux density. [PDF]

RSC Adv, 2023
Dong H, Li X, Xu X, Lu Z.
europepmc   +1 more source

Flux creep in type-II superconductors: self-organized criticality approach

, 2004
We consider the current density distribution function of a flux creep regime in type-II superconductors by mapping the flux creep process to the dynamics of a model with a self-organized criticality. We use an extremal Robin Hood type model which evolves
A. I. Larkin, A. I. Larkin, A. M. Campbell, H. J. Jensen, Ilya Papiashvili, L. I. Glazman, L. I. Glazman, P. Bak, P. G. de Gennes, R. G. Mints   +9 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Photosynthetic Photon Flux Density Effects on Portulaca olearacea in Controlled-Environment Agriculture. [PDF]

Plants (Basel), 2023
Kudirka G, Viršilė A, Laužikė K, Sutulienė R, Samuolienė G.   +4 more
europepmc   +1 more source