Results 111 to 120 of about 5,574,042 (346)

Magnetism in SQUIDs at Millikelvin Temperatures

, 2008
We have characterized the temperature dependence of the flux threading dc SQUIDs cooled to millikelvin temperatures. The flux increases as 1/T as temperature is lowered; moreover, the flux change is proportional to the density of trapped vortices.
A. Kittel, D. Hover, J. Clarke, John M. Martinis, L. Faoro, M. Mück, R. McDermott, S. Sendelbach   +7 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Tunable pseudogap Kondo effect and quantum phase transitions in Aharonov-Bohm interferometers

, 2009
We study two quantum dots embedded in the arms of an Aharonov-Bohm ring threaded by a magnetic flux. The system can be described by an effective one-impurity Anderson model with an energy- and flux-dependent density of states.
da Silva, Luis G. G. V. Dias, Ingersent, Kevin, Sandler, Nancy, Simon, Pascal, Ulloa, Sergio E.   +4 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A 12um ISOCAM Survey of the ESO-Sculptor Field: Data Reduction and Analysis

, 2007
We present a detailed reduction of a mid-infrared 12um (LW10 filter) ISOCAM open time observation performed on the ESO-Sculptor Survey field (Arnouts et al. 1997).
Abergel, Arnouts, Aussel, B. Rocca-Volmerange, Bertin, Bessell, Cesarsky, Clements, Cohen, de Lapparent, de Lapparent, Désert, Efstathiou, Gallagher, Gruppioni, Kessler, Lari, Lejeune, N. Seymour, Oliver, Pozzi, Pozzi, Reid, Rocca-Volmerange, Rodighiero, Rué, Schlegel, Serjeant, Starck, V. de Lapparent, Vaccari, Väisänen, Waters   +32 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Effect of photon flux density on bud dormancy release in Norway spruce seedlings.

Silva Fennica, 1991
The effect of photon flux density on bud dormancy release in two-year-old seedlings of Norway spruce ( (L.) H. Karst.) was examined. The seedlings were first chilled for 0–21 weeks under natural conditions and then forced in a warm greenhouse either in
Höyhtyä, Riitta, Hänninen, Heikki
doaj   +1 more source

Constraining annual and seasonal radon-222 flux density from the Southern Ocean using radon-222 concentrations in the boundary layer at Cape Grim

, 2013
Radon concentrations measured between 2001 and 2008 in marine air at Cape Grim, a baseline site in north-western Tasmania, are used to constrain the radon flux density from the Southern Ocean.
W. Zahorowski, A. Griffiths, S. Chambers, A. Williams, R. Law, J. Crawford, S. Werczynski   +6 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source